SUMMARY: The Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ) is an exposed necrotic alveolar bone associated with intravenous (IV) administration of Bisphosphonate (BP) therapy of multiple myeloma and bone metastases without previous radiation therapy (RT) to the maxillo-facial region (1,2,3). Hyperbaric Oxygen (HBO) treatment is one of the option which used on treatment of BRONJ, via increasing stem cell mobilisation, decreasing oedema, inflammation, and accelerating to wound healing (4,5). In this report, the case with metastatic breast cancer who has BRONJ was presented, and treatment of BRONJ with HBO was discussed.
ÖZET: Bifosfonata bağlı çene osteonekrozisi (BBCO) kemik metastazı veya multipl myeloma’da kullanılan intravenöz bifosfonat ile ilişkili, daha önce radyoterapi uygulanmamış maksillofasiyal bölge alveoler kemiklerinin nekrozudur (1,2,3). Hiperbarik oksijen (HBO) kök hücre mobilizasyonu arttırma, ödem, inflamasyonu azaltma ve hasar iyileşmesini hızlandıraması yoluyla, BBCO tedavisinde kullanılan seçeneklerden biridir (4,5). Bu raporda metastatik meme kanserli bir BBCO olgusu sunulacak ve BBCO tedavisinde HBO tartışılacaktır.
Primary Language | Turkish |
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Journal Section | OLGU SUNUMU |
Authors | |
Publication Date | June 18, 2015 |
Published in Issue | Year 2013 Volume: 35 Issue: 3 - OSMANGAZİ TIP DERGİSİ / Osmangazi Journal of Medicine |