Oral Skuamöz Hücreli Karsinom Vakalarında Boyun Diseksiyonu: Ne Zaman, Hangi Prosedür?
Yıl 2020,
Ağız Kanserleri Özel Sayısı, 119 - 127, 28.09.2020
Göksel Tımarcıoğlu
,
Semiha Seda Şahin
,
İlker Burgaz
Celal Çandırlı
Öz
Oral bölgede en sık görülen malign tümör skuamöz hücreli karsinom (shk)’dur. Shk’nın en iyi sonuç veren tedavi seçeneği cerrahi tedaviyle birlikte radyoterapi/kemoterapi olarak bilinmektedir. Boyun diseksiyonu (bd) tipine karar verirken TNM sınıflaması göz önünde bulundurulmalıdır. Bu çalışmadaki amaç; oral shk’da boyun diseksiyonu (bd) prosedürlerini tanımlamak ve olgu raporları ile prosedürleri örneklendirmektir. 2016-2019 yılları arasında başvuran ve tedavi edilen 9 oral shk’li hasta sunulmuştur. 7 hastaya tek taraflı elektif subraomohiyoid bd, 1 hastaya tek taraflı tedavi edici modifiye radikal(fonksiyonel) bd, 1 hastaya çift taraflı tedavi edici modifiye radikal (fonksiyonel) bd uygulanmıştır. Doğru endikasyon ile boyun diseksiyonu prosedürlerinin seçimi mikroinvazyon ve metastaz riskini azaltmasının yanı sıra cerrahi sonrası morbiditeyi de azaltmaktadır. Mikroinvazyon riskini ekarte etmek için N0 hastalarda elektif bd, N(+) hastalarda ipsilateral tedavi edici bd ile birlikte kontralateral elektif bd uygulanabilmektedir. Cerrahi morbiditeyi azaltmak için boyun anatomik yapılarının korunması ve oral shk’da sık metastaz görülen boyun düzeylerinin temizlenmesi önem arz etmektedir.
Kaynakça
- Rivera C. Essentials of oral cancer. Int J Clin Exp Pathol. 2015;8(9):11884-94.
- Cancer stat facts: oral cavity and pharynx cancer. [national cancer instutite surveillance, epidemiology, and end results program] 2020. https://seer.cancer.gov/statfacts/html/oralcav.html
- Rose BS, Jeong JH, Nath SK, et al. Populationbased study of competing mortality in head and neck cancer. J Clin Oncol 2011;29:3503–9.
- Woolgar JA, Triantafyllou A, Lewis JS Jr. Prognostic biological features in neck dissection specimens. Eur Arch Otorhinolaryngol 2013;270:1581–92.
- Afzali P, Ward BB. Management of the neck in oral squamous cell carcinoma: background, classification, and current philosophy. Oral Maxillofac Surg Clin North Am. 2019;31(1):69-84.
- Edge SB, Byrd DR, Compton CC, et al, editors. (2010), AJCC cancer staging manual. 7th ed. New York: Springer.
- Montero PH, Patel SG. Cancer of the oral cavity, Surg Oncol Clin N Am. 2015; 24(3): 491–508.
- Robbins KT, Clayman G, Levine PA, et al. Neck dissection classification update: revision proposed by the American Head and Neck Society and the American Academy of Otolaryngology-Head and Neck Surgery. Arch Otolaryngol Head Neck Surg. 2002;128(7):751-8.
- Robbins KT; Shaha AR; Medina JE. Consensus statement on the classification and terminology of neck dissection, Arch Otolaryngol Head Neck Surg. 2008;134(5):536-538.
- Ibrahim SA, Ahmed ANA, Elsersy HA,et al. Elective neck dissection in T1/T2 oral squamous cell carcinoma with N0 neck: essential or not? a systematic review and meta-analysis. Eur Arch Otorhinolaryngol. 2020 Feb 25. doi: 10.1007/s00405-020-05866-3.
- Amin MB, Edge SB, Greene FL, et al, editors. (2017), AJCC cancer staging manual. 8th ed. New York: Springer.
Neck dissection in oral scuamous cell carcinoma cases: when, which procedure?
Yıl 2020,
Ağız Kanserleri Özel Sayısı, 119 - 127, 28.09.2020
Göksel Tımarcıoğlu
,
Semiha Seda Şahin
,
İlker Burgaz
Celal Çandırlı
Öz
The most common malignant tumor in the oral region is squamous cell carcinoma (scc). The best treatment option of scc is known as surgical treatment combined with radiotherapy/chemotherapy. When deciding on the type of neck dissection (nd), the TNM classification should be considered. The purpose of this study; to describe nd procedures in oral scc and to illustrate procedures. 9 oral scc patients who were admitted and treated between 2016-2019, were presented. Unilateral elective subraomohyoid nd was performed in 7 patients. Unilateral therapeutic modified radical(functional) nd was performed in one patient. Bilateral therapeutic modified radical(functional) nd was performed in one patient. Choosing neck dissection procedures with the correct indication not only reduces the risk of microinvasion, but also reduces postoperative morbidity. Elective nd is performed in N0 patients to rule out the risk of microinvasion. In N+ patients, ipsilateral therapeutic nd can be combined with contralateral elective nd.
Kaynakça
- Rivera C. Essentials of oral cancer. Int J Clin Exp Pathol. 2015;8(9):11884-94.
- Cancer stat facts: oral cavity and pharynx cancer. [national cancer instutite surveillance, epidemiology, and end results program] 2020. https://seer.cancer.gov/statfacts/html/oralcav.html
- Rose BS, Jeong JH, Nath SK, et al. Populationbased study of competing mortality in head and neck cancer. J Clin Oncol 2011;29:3503–9.
- Woolgar JA, Triantafyllou A, Lewis JS Jr. Prognostic biological features in neck dissection specimens. Eur Arch Otorhinolaryngol 2013;270:1581–92.
- Afzali P, Ward BB. Management of the neck in oral squamous cell carcinoma: background, classification, and current philosophy. Oral Maxillofac Surg Clin North Am. 2019;31(1):69-84.
- Edge SB, Byrd DR, Compton CC, et al, editors. (2010), AJCC cancer staging manual. 7th ed. New York: Springer.
- Montero PH, Patel SG. Cancer of the oral cavity, Surg Oncol Clin N Am. 2015; 24(3): 491–508.
- Robbins KT, Clayman G, Levine PA, et al. Neck dissection classification update: revision proposed by the American Head and Neck Society and the American Academy of Otolaryngology-Head and Neck Surgery. Arch Otolaryngol Head Neck Surg. 2002;128(7):751-8.
- Robbins KT; Shaha AR; Medina JE. Consensus statement on the classification and terminology of neck dissection, Arch Otolaryngol Head Neck Surg. 2008;134(5):536-538.
- Ibrahim SA, Ahmed ANA, Elsersy HA,et al. Elective neck dissection in T1/T2 oral squamous cell carcinoma with N0 neck: essential or not? a systematic review and meta-analysis. Eur Arch Otorhinolaryngol. 2020 Feb 25. doi: 10.1007/s00405-020-05866-3.
- Amin MB, Edge SB, Greene FL, et al, editors. (2017), AJCC cancer staging manual. 8th ed. New York: Springer.