Investigation Of Clinical, Laboratory and Radiological Results of Novel Coronavirus Disease (Covid-19) Novel Coronavirus Disease

Year 2021, Volume: 43 Issue: 4, 332 - 340, 18.05.2021

Musa Kaya Muhammed Emin Demirkol

https://doi.org/10.20515/otd.867956

Abstract

Covid-19, which emerged in China in December 2019 and spread to the whole world in a short time, has been a serious public health problem threatening humanity. In this study, we aimed to reveal demographic, clinical, laboratory and radiological features of patients diagnosed with Covid-19. The study is a retrospective cross-sectional study consisting of patients who were hospitalized in health institutions in Bolu, Turkey between 11.03.2020 and 19.04.2020 with a definitive or probable diagnosis of Covid-19. The number of patients in the study was 262. The mean age of the patients participating in the study was 57.39 ± 19.85, the youngest patient was 19 and the oldest was 94 years old. Of the patients, 40.1% was between the ages of 18-50, 59.9% were over 50 years old. 55.3% of the patients were women and 44.7% were men. Most common symptoms were fever (75.6%), cough (71.8%) and dyspnea (46.9%). Elevated CRP (in 71.3%), elevated LDH (in 56.9%), elevated D-DIMER (in 56.4%) and lymphopenia (in 30.5) were most detected laboratory abnormalities. The result of the real-time reverse-transcription polymerase chain reaction (RT-PCR) test was positive in 35.5% of 262 patients. 88.5% of the patients had chest CT findings compatible with Covid-19. Additionally, 24% had both positive RT-PCR results and CT findings compatible with Covid-19. Expected findings were found to be in older patients more than younger ones. We suggest that clinical features, laboratory abnormalities and radiological findings can be used to provide an early diagnosis and treatment of Covid-19.

Keywords

Covid-19, clinical features, radiological findings, laboratory findings

Supporting Institution

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Project Number

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Yeni Koronavirüs Hastalığının (Covid-19) Klinik, Laboratuvar ve Radyolojik Sonuçlarının İncelenmesi

Abstract

Aralık 2019'da Çin'de ortaya çıkan ve kısa sürede tüm dünyaya yayılan Covid-19, insanlığı tehdit eden ciddi bir halk sağlığı sorunu olmuştur. Bu çalışmada Covid-19 tanısı alan hastaların demografik, klinik, laboratuvar ve radyolojik özelliklerini ortaya çıkarmayı amaçladık. Çalışma, 11.03.2020 ile 19.04.2020 tarihleri arasında Bolu ilindeki sağlık kuruluşlarında kesin veya olası Covid-19 tanısı ile hastaneye yatırılan hastalardan oluşan retrospektif kesitsel bir çalışmadır. Çalışmaya katılan hasta sayısı 262 idi. Çalışmaya katılan hastaların yaş ortalaması 57.39 ± 19.85, en genç hasta 19 ve en yaşlı hasta 94 idi. Hastaların% 40.1'i 18-50 yaş aralığında,% 59.9'u 50 yaşın üzerindeydi. Hastaların% 55,3'ü kadın,% 44,7'si erkekti. En sık görülen semptomlar ateş (% 75,6), öksürük (% 71,8) ve nefes darlığı (% 46,9) idi. Yüksek CRP (% 71.3'te), yüksek LDH (% 56.9'da), yükselmiş D-DIMER (% 56.4'te) ve lenfopeni (30.5'te) saptanan laboratuar anormallikleriydi. Gerçek zamanlı ters transkripsiyon polimeraz zincir reaksiyonu (RT-PCR) testinin sonucu 262 hastanın% 35,5'inde pozitifti. Hastaların% 88,5'inde Covid-19 ile uyumlu göğüs BT bulguları vardı. Ek olarak,% 24'ü hem pozitif RT-PCR sonuçlarına hem de Covid-19 ile uyumlu BT bulgularına sahipti. Beklenen bulguların, gençlere göre yaşlı hastalarda daha fazla olduğu bulundu. Covid-19'un erken tanı ve tedavisi için klinik özelliklerin, laboratuvar anormalliklerinin ve radyolojik bulguların kullanılabileceğini önermekteyiz

Keywords

covid-19, klinik özellikler, radyolojik bulgular, laboratuvar bulguları

Project Number

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