Cognitive dysfunction is a core feature of schizophrenia. It can manifest itself in various fields, with different intensities, including cognitive executive functions. At the same time, neurocognitive disorders have negative effects on quality of life. Our study aimed to investigate the relationship of neurocognitive impairment with disease duration, quality of life and sociodemographic characteristics in patients with schizophrenia. 100 patients diagnosed with schizophrenic disorder who are treated as outpatients or inpatients in Çukurova University Faculty of Medicine Balcalı Hospital, Department of Psychiatry constitute the sample group of this study. In addition, 80 healthy people from the general population with similar gender and age were included in the study as a control group. In addition to the sociodemographic data form created by us for the control group, Frontal Evaluation Battery (FEB), World Health Organization Quality of Life Scale Shortened Version (WHOQOL-BREF) scales and Positive and Negative Syndrome Scale (PANNS) was applied. The difference between the mean FDB score of those who were in the first 5 years of their disease and those who were sick for more than 5 years was found to be statistically significant (p=0.008). A significant difference was found between the mean scores of the quality of life (p=0.001) and FDB (p=0.02) scales according to the number of hospitalizations. A significant difference was found between the mean scores of quality of life (p=0.001) and FDB (p<0.001) scale scores in the patient group according to education level. The difference between the quality of life (p=0.01) and FDB (p=0.01) scale mean scores of those with and without a family history was found to be significant. According to the results of our study, neurocognitive effects were observed less in the first five years of the disease, in those with higher education levels, and in workers, and the quality of life was higher. As the number of hospitalizations increased, cognitive functions were more affected. It was determined that cognitive dysfunction was more common in patients with higher disease duration and PANSS scale scores. In the first years of the disease, early diagnosis, treatment and rehabilitation, and social support studies should be carried out in order to improve the education life and employment of the patients and to lead a better quality life.
|Subjects||Health Care Sciences and Services|
|Journal Section||ORİJİNAL MAKALE|
|Publication Date||November 28, 2022|
|Published in Issue||Year 2022, Volume 44, Issue 6|