Case Report
BibTex RIS Cite

Parkinson Hastalığına Sekonder Ogilvie Sendromu: Yanlış Bir Tanı

Year 2023, Volume: 45 Issue: 2, 301 - 305, 15.03.2023

Abstract

Parkinson hastalığının (PH) sürecinin bir parçası olarak otonomik disfonksiyon gelişebilmektedir. Gastrointestinal disfonksiyon da disotonominin en yaygın belirtilerinden biridir. Parkinson hastalığında genellikle kolonda pseudo-obstruksiyon (Ogilvie sendromu), olarak adlandırılan mekanik bir obstrüksiyon olmadan ileri derecede kolon dilatasyonu ile karakterize paralitik ileus gelişmektedir. Ancak ayrıcı tanıda mutlaka mekanik obstruksiyon yapan nedenler düşünülmelidir. Biz bu çalışmada öncelikle Ogilvie sendromu düşünülen ancak kitleye ikincil mekanik ileus saptanan PH hastasını sunmayı amaçladık.

References

  • 1. Pfeiffer RF. Autonomic Dysfunction in Parkinson’s Disease. Vol. 17, Neurotherapeutics. Springer Science and Business Media Deutschland GmbH; 2020. p. 1464–79.
  • 2. Warnecke T, Schäfer KH, Claus I, del Tredici K, Jost WH. Gastrointestinal involvement in Parkinson’s disease: pathophysiology, diagnosis, and management. Vol. 8, npj Parkinson’s Disease. Nature Research; 2022.
  • 3. Echchikhi M, Essaber H, Sekkat H, Laamrani FZ, Jroundi L. Ogilvie Syndrome Associated to Parkinson’s Disease. Open J Clin Diagn. 2019;09:65–70.
  • 4. Savica R, Carlin JM, Grossardt BBR, Bower JH, Ahlskog JE, Maraganore DM, et al. Medical records documentation of constipation preceding Parkinson disease A case-control study. 2009.
  • 5. Edwards LL, Quigley EM, Harned RK, Hofman R, Pfeiffer RF. Characterization of swallowing and defecation in Parkinson’s disease. Am J Gastroenterol. 1994;89:15–25.
  • 6. Byrne KG, Pfeiffer R, Quigley EMM. Gastrointestinal Dysfunction in Parkinson???s Disease. J Clin Gastroenterol. 1994;19:11–6.
  • 7. Ueki A, Otsuka M. Life style risks of Parkinson?s disease: Association between decreased water intake and constipation. J Neurol. 2004;251(S7):vii18–23.
  • 8. Ashraf W, Pfeiffer RF, Park F, Lof J, Quigley EMM. Constipation in parkinson’s disease: Objective assessment and response to psyllium. Movement Disorders. 1997;12:946–51.
  • 9. Jager WADH, Bethlem J. The Distribution Of Lewy Bodies In The Central And Autonomic Nervous Systems In Idiopathic Paralysis Agitans. J Neurol Neurosurg Psychiatry. 1960;23:283–90.
  • 10. Wakabayashi K, Takahashi H, Takeda S, Ohama E, Ikuta F. Parkinson’s disease: the presence of Lewy bodies in Auerbach’s and Meissner’s plexuses. Acta Neuropathol. 1988;76:217–21.
  • 11. Kupsky WJ, Grimes MM, Sweeting J, Bertsch R, Cote LJ. Parkinson’s disease and megacolon: Concentric hyaline inclusions (Lewy bodies) in enteric ganglion cells. Neurology. 1987 Jul 1;37:1253–1253.
  • 12. Bloch A, Probst A, Bissig H, Adams H, Tolnay M. alpha-Synuclein pathology of the spinal and peripheral autonomic nervous system in neurologically unimpaired elderly subjects. Neuropathol Appl Neurobiol. 2006;32:284–95.
  • 13. Probst A, Bloch A, Tolnay M. New insights into the pathology of Parkinson’s disease: does the peripheral autonomic system become central? Eur J Neurol. 2008 ;15(s1):1–4.
  • 14. Beach TG, Adler CH, Sue LI, Vedders L, Lue L, White III CL, et al. Multi-organ distribution of phosphorylated α-synuclein histopathology in subjects with Lewy body disorders. Acta Neuropathol. 2010;119:689–702.
  • 15. Stokholm MG, Danielsen EH, Hamilton-Dutoit SJ, Borghammer P. Pathological α-synuclein in gastrointestinal tissues from prodromal Parkinson disease patients. Ann Neurol. 2016 ;79:940–9.
  • 16. Killinger BA, Madaj Z, Sikora JW, Rey N, Haas AJ, Vepa Y, et al. The vermiform appendix impacts the risk of developing Parkinson’s disease. Sci Transl Med. 2018 t 31;10(465).
  • 17. Braak H, de Vos RAI, Bohl J, del Tredici K. Gastric α-synuclein immunoreactive inclusions in Meissner’s and Auerbach’s plexuses in cases staged for Parkinson’s disease-related brain pathology. Neurosci Lett. 2006 ;396:67–72.
  • 18. Klos KJ, Ahlskog JE, Josephs KA, Apaydin H, Parisi JE, Boeve BF, et al. α-Synuclein pathology in the spinal cords of neurologically asymptomatic aged individuals. Neurology.2006 11;66:1100–2.
  • 19. Braak H, Sastre M, Bohl JRE, de Vos RAI, del Tredici K. Parkinson’s disease: lesions in dorsal horn layer I, involvement of parasympathetic and sympathetic pre- and postganglionic neurons. Acta Neuropathol. 2007 ;113:421–9.
  • 20. Minguez-Castellanos A, Chamorro CE, Escamilla-Sevilla F, Ortega-Moreno A, Rebollo AC, Gomez-Rio M, et al. Do -synuclein aggregates in autonomic plexuses predate Lewy body disorders?: A cohort study. Neurology. 2007;68:2012–8.
  • 21. Spencer NJ, Hu H. Enteric nervous system: sensory transduction, neural circuits and gastrointestinal motility. Nat Rev Gastroenterol Hepatol. 2020;17:338–51.
  • 22. Tateno F, Sakakibara R, Aiba Y, Ogata T, Katsumata M, Matsuoka Y. Recurrent sigmoid volvulus in a patient with Parkinson’s disease. Vol. 30, Clinical Autonomic Research. Springer; 2020. p. 283–5.
  • 23. Ross SW, Oommen B, Wormer BA, Walters AL, Augenstein VA, Heniford BT, et al. Acute Colonic Pseudo-obstruction: Defining the Epidemiology, Treatment, and Adverse Outcomes of Ogilvie’s Syndrome. Am Surg. 2016 ;82:102–11.
  • 24. Yokoyama T HI. Ileus in Parkinson’s disease. Neurol Med . 2007;66:6–11.
  • 25. Tateno F, Sakakibara R, Kishi M, Ogawa E, Yoshimatsu Y, Takada N, et al. Incidence of emergency intestinal Pseudo-obstruction in Parkinson’s disease. Vol. 59, Journal of the American Geriatrics Society. 2011. p. 2373–5.

Ogilvie’s Syndrome Secondary to Parkinson’s disease: A Dangerous Misdiagnosis

Year 2023, Volume: 45 Issue: 2, 301 - 305, 15.03.2023

Abstract

Autonomic dysfunction may develop as part of the process of Parkinson's disease (PD). Gastrointestinal dysfunction is also one of the most common manifestations of dysautonomia. Paralytic ileus, which is characterized by severe colonic dilatation without mechanical obstruction, usually develops in PD, called pseudo-obstruction of the colon (Ogilvie's syndrome). However, causes of mechanical obstruction should be considered in the differential diagnosis. In this study, we aimed to present a PD patient who was initially thought to have Ogilvie’s syndrome but was found to have mechanical ileus.

References

  • 1. Pfeiffer RF. Autonomic Dysfunction in Parkinson’s Disease. Vol. 17, Neurotherapeutics. Springer Science and Business Media Deutschland GmbH; 2020. p. 1464–79.
  • 2. Warnecke T, Schäfer KH, Claus I, del Tredici K, Jost WH. Gastrointestinal involvement in Parkinson’s disease: pathophysiology, diagnosis, and management. Vol. 8, npj Parkinson’s Disease. Nature Research; 2022.
  • 3. Echchikhi M, Essaber H, Sekkat H, Laamrani FZ, Jroundi L. Ogilvie Syndrome Associated to Parkinson’s Disease. Open J Clin Diagn. 2019;09:65–70.
  • 4. Savica R, Carlin JM, Grossardt BBR, Bower JH, Ahlskog JE, Maraganore DM, et al. Medical records documentation of constipation preceding Parkinson disease A case-control study. 2009.
  • 5. Edwards LL, Quigley EM, Harned RK, Hofman R, Pfeiffer RF. Characterization of swallowing and defecation in Parkinson’s disease. Am J Gastroenterol. 1994;89:15–25.
  • 6. Byrne KG, Pfeiffer R, Quigley EMM. Gastrointestinal Dysfunction in Parkinson???s Disease. J Clin Gastroenterol. 1994;19:11–6.
  • 7. Ueki A, Otsuka M. Life style risks of Parkinson?s disease: Association between decreased water intake and constipation. J Neurol. 2004;251(S7):vii18–23.
  • 8. Ashraf W, Pfeiffer RF, Park F, Lof J, Quigley EMM. Constipation in parkinson’s disease: Objective assessment and response to psyllium. Movement Disorders. 1997;12:946–51.
  • 9. Jager WADH, Bethlem J. The Distribution Of Lewy Bodies In The Central And Autonomic Nervous Systems In Idiopathic Paralysis Agitans. J Neurol Neurosurg Psychiatry. 1960;23:283–90.
  • 10. Wakabayashi K, Takahashi H, Takeda S, Ohama E, Ikuta F. Parkinson’s disease: the presence of Lewy bodies in Auerbach’s and Meissner’s plexuses. Acta Neuropathol. 1988;76:217–21.
  • 11. Kupsky WJ, Grimes MM, Sweeting J, Bertsch R, Cote LJ. Parkinson’s disease and megacolon: Concentric hyaline inclusions (Lewy bodies) in enteric ganglion cells. Neurology. 1987 Jul 1;37:1253–1253.
  • 12. Bloch A, Probst A, Bissig H, Adams H, Tolnay M. alpha-Synuclein pathology of the spinal and peripheral autonomic nervous system in neurologically unimpaired elderly subjects. Neuropathol Appl Neurobiol. 2006;32:284–95.
  • 13. Probst A, Bloch A, Tolnay M. New insights into the pathology of Parkinson’s disease: does the peripheral autonomic system become central? Eur J Neurol. 2008 ;15(s1):1–4.
  • 14. Beach TG, Adler CH, Sue LI, Vedders L, Lue L, White III CL, et al. Multi-organ distribution of phosphorylated α-synuclein histopathology in subjects with Lewy body disorders. Acta Neuropathol. 2010;119:689–702.
  • 15. Stokholm MG, Danielsen EH, Hamilton-Dutoit SJ, Borghammer P. Pathological α-synuclein in gastrointestinal tissues from prodromal Parkinson disease patients. Ann Neurol. 2016 ;79:940–9.
  • 16. Killinger BA, Madaj Z, Sikora JW, Rey N, Haas AJ, Vepa Y, et al. The vermiform appendix impacts the risk of developing Parkinson’s disease. Sci Transl Med. 2018 t 31;10(465).
  • 17. Braak H, de Vos RAI, Bohl J, del Tredici K. Gastric α-synuclein immunoreactive inclusions in Meissner’s and Auerbach’s plexuses in cases staged for Parkinson’s disease-related brain pathology. Neurosci Lett. 2006 ;396:67–72.
  • 18. Klos KJ, Ahlskog JE, Josephs KA, Apaydin H, Parisi JE, Boeve BF, et al. α-Synuclein pathology in the spinal cords of neurologically asymptomatic aged individuals. Neurology.2006 11;66:1100–2.
  • 19. Braak H, Sastre M, Bohl JRE, de Vos RAI, del Tredici K. Parkinson’s disease: lesions in dorsal horn layer I, involvement of parasympathetic and sympathetic pre- and postganglionic neurons. Acta Neuropathol. 2007 ;113:421–9.
  • 20. Minguez-Castellanos A, Chamorro CE, Escamilla-Sevilla F, Ortega-Moreno A, Rebollo AC, Gomez-Rio M, et al. Do -synuclein aggregates in autonomic plexuses predate Lewy body disorders?: A cohort study. Neurology. 2007;68:2012–8.
  • 21. Spencer NJ, Hu H. Enteric nervous system: sensory transduction, neural circuits and gastrointestinal motility. Nat Rev Gastroenterol Hepatol. 2020;17:338–51.
  • 22. Tateno F, Sakakibara R, Aiba Y, Ogata T, Katsumata M, Matsuoka Y. Recurrent sigmoid volvulus in a patient with Parkinson’s disease. Vol. 30, Clinical Autonomic Research. Springer; 2020. p. 283–5.
  • 23. Ross SW, Oommen B, Wormer BA, Walters AL, Augenstein VA, Heniford BT, et al. Acute Colonic Pseudo-obstruction: Defining the Epidemiology, Treatment, and Adverse Outcomes of Ogilvie’s Syndrome. Am Surg. 2016 ;82:102–11.
  • 24. Yokoyama T HI. Ileus in Parkinson’s disease. Neurol Med . 2007;66:6–11.
  • 25. Tateno F, Sakakibara R, Kishi M, Ogawa E, Yoshimatsu Y, Takada N, et al. Incidence of emergency intestinal Pseudo-obstruction in Parkinson’s disease. Vol. 59, Journal of the American Geriatrics Society. 2011. p. 2373–5.
There are 25 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section OLGU SUNUMU
Authors

Aydan Topal 0000-0002-8332-9076

Fatma Nazlı Durmaz Çelik 0000-0002-2943-2240

Serhat Özkan 0000-0002-5874-5270

Publication Date March 15, 2023
Published in Issue Year 2023 Volume: 45 Issue: 2

Cite

Vancouver Topal A, Durmaz Çelik FN, Özkan S. Ogilvie’s Syndrome Secondary to Parkinson’s disease: A Dangerous Misdiagnosis. Osmangazi Tıp Dergisi. 2023;45(2):301-5.


13299        13308       13306       13305    13307  1330126978