Pediatric Tuberculosis In Turkey: A Review of 5-years Period In A Tertiary Care Hospital

Yıl 2023, Cilt: 45 Sayı: 5, 724 - 731, 27.09.2023

Merve İşeri Nepesov , Yalçın Kara , Mahmut Can Kızıl , Yusuf Aydemir , Zeren Barış , Ömer Kılıç , Koray Harmanci , Ener Çağrı Dinleyici

https://doi.org/10.20515/otd.1251197

Öz

Tuberculosis is a public health problem that still maintains importance in all developed and developing countries. In childhood tuberculosis, unlike adults, presenting less classical findings and the low rate of detection of the agent by microbiological methods create difficulties in diagnosis. The aim of this study was to evaluate the clinical, laboratory and radiological findings of patients followed up with the diagnosis of tuberculosis disease in our clinic. Thirty-four patients who were followed up with the diagnosis of tuberculosis disease in our clinic on January 2014-December 2019 were included in the study and the files of the patients were reviewed retrospectively. Fifty percent (n:17) of the patients were male, with a median age of diagnosis was 153.5 mos (17-218 months). Thirteen patients were diagnosed with pulmonary, 8 patients with disseminated, 6 patients with gastrointestinal, 6 patients with lymph node and 1 patient with joint tuberculosis. While there were 8 (23.5%) patients with a history of tuberculosis contact, the most common complaints were cough, abdominal pain, weight loss and fever. Eight (23.5%) patients had no pathological findings at the time of admission. While tuberculine skin test was positive in 17 (50%) patients, tubercle bacillus was demonstrated by microbiological methods in seven patients. One patient diagnosed tuberculosis disease by, with a positive response to treatment and exclusion of other diseases. While the treatment was interrupted for a short time due to side effects in four (11.8%) patients, no serious side effects were observed in any of the patients. The diagnosis is made by combining clinical, laboratory and radiological findings, and sometimes patients can be diagnosed with the positive response of the patient to the treatment.

Anahtar Kelimeler

Çocuk, Mycobacterium tuberculosis, public health

Türkiye'de Pediatrik Tüberküloz: Üçüncü Basamak Bir Hastanede 5 Yıllık Sürecin Değerlendirilmesi

Öz

Tüberküloz gelişmiş ve gelişmekte olan tüm ülkelerde halen önemini koruyan bir halk sağlığı sorunudur. Çocukluk çağı tüberkülozunda erişkinden farklı olarak klasik bulguların daha az görülmesi ve mikrobiyolojik yöntemlerle etkenin gösterilme oranının düşük olması tanıdaki zorlukları oluşturur. Bu çalışma ile kliniğimizde tüberküloz hastalığı tanısı ile takip edilen hastaların klinik, laboratuvar ve radyolojik bulgularının değerlendirilmesi amaçlanmıştır. Çalışmaya kliniğimizde Ocak 2014-Aralık 2019 tarihleri arasında tüberküloz hastalığı tanısı ile izlenen 34 hasta dahil edilmiş olup hastaların dosyaları retrospektif olarak incelenmiştir. Hastaların %50’si (n:17) erkek olup tanı yaşı ortancası 153.5 aydır (aralık 17-218 ay). On üç hasta pulmoner, 8 hasta dissemine, 6 hasta gastrointestinal tüberküloz tanısı alırken; 6 hasta lenf nodu, 1 hasta eklem tüberkülozu tanısı almıştır. Tüberküloz temas öyküsü 8 (%23.5) hastada bulunmakta iken en sık başvuru şikayeti öksürük, karın ağrısı, kilo kaybı ve ateşti. Sekiz (%23.5) hastada başvuru sırasında patolojik muayene bulgusu saptanmamıştır. On yedi (%50) hastada tüberkülin deri testi pozitifliği mevcut iken yedi hastada tüberküloz basili mikrobiyolojik yöntemlerle gösterilmiştir. Bir hastada tedaviye verdiği olumlu yanıt ve diğer hastalıkların dışlanması ile tüberküloz hastalığı tanısı konulmuştur. Dört (%11.8) hastada yan etki nedeniyle tedaviye kısa süreli ara verilirken hiçbir hastada ciddi yan etki gözlenmemiştir. Tanı klinik, laboratuvar ve radyolojik bulguların bir araya getirilmesi ile konulmakta olup, kimi zaman hastanın tedaviye verdiği olumlu cevap ile hastalar tanı alabilmektedir.

Anahtar Kelimeler

Çocuk, Mycobacterium tuberculosis, halk sağlığı

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