Geriatrik Yaşta Beyin Sağlığını Korumada Takviye Kullanımı

Yıl 2025, Cilt: 47 Sayı: Beyin Farkındalığı 2025 Özel Sayısı, 24 - 33, 22.08.2025

Yelda Öztürk

Öz

In the geriatric population, supplement use for the purpose of preserving brain health and supporting cognitive functions has become increasingly prevalent. The most frequently studied supplements include vitamins, minerals, omega 3 fatty acids, Ginkgo biloba leaf extract, curcumin and resveratrol (as polyphenols), coenzyme Q10, St. John's wort (Hypericum perforatum), melatonin, and probiotics/prebiotics. Although some studies show promising results, there is no definitive and robust evidence at present to recommend the routine use of any supplement specifically for brain health preservation. The fundamental principle remains deficiency-based repletion. Age-related physiological changes, multimorbidity, and polypharmacy increase the risk of drug–nutrient interactions. It is essential to foster awareness of the safe dosage range, potential adverse effects, and drug interactions. Consequently, a comprehensive geriatric assessment should be conducted for every older adult, including a thorough inquiry about supplement use, and a personalized approach to supplementation should be adopted.

Anahtar Kelimeler

vitamin , mineral , antioksidan , diyet takviyesi , demans , kognitif fonksiyon

Use of Supplements to Preserve Brain Health in Geriatric Age

Öz

In the geriatric population, supplement use for the purpose of preserving brain health and supporting cognitive functions has become increasingly prevalent. The most frequently studied supplements include vitamins, minerals, omega 3 fatty acids, Ginkgo biloba leaf extract, curcumin and resveratrol (as polyphenols), coenzyme Q10, St. John's wort (Hypericum perforatum), melatonin, and probiotics/prebiotics. Although some studies show promising results, there is no definitive and robust evidence at present to recommend the routine use of any supplement specifically for brain health preservation. The fundamental principle remains deficiency-based repletion. Age-related physiological changes, multimorbidity, and polypharmacy increase the risk of drug–nutrient interactions. It is essential to foster awareness of the safe dosage range, potential adverse effects, and drug interactions. Consequently, a comprehensive geriatric assessment should be conducted for every older adult, including a thorough inquiry about supplement use, and a personalized approach to supplementation should be adopted.

Anahtar Kelimeler

Vitamin , mineral , antioxidant , dietary supplement , dementia , cognitive function

Kaynakça

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