The Relationship between Cloninger’s Temperament and Character Dimensions, and Depression Treatment Outcome

Abstract

Objective: The aim of our study is to investigate the relationship between Temperament and Character Inventory (TCI) dimensions and treatment response in Major Depressive Disorder (MDD) patients.

Materials and Methods: 88 patients diagnosed with MDD were included in the study. Patients were given Sociodemographic Data Form, Beck Depression Inventory (BDI) and TCI before the treatment. According to the BDI, which was applied 8 weeks after the treatment, the patients were divided into two groups as those who responded to the treatment and those who did not (responders and non-responders).

Results: The education level of the patients was statistically higher in the responders. The number of unemployed (92.3%) patients in the non-responders was statistically higher than the number of unemployed (41.3%) patients in the responders. The number of patients with severe depression was statistically significantly higher in the non-responders. The mean harm avoidence score of the patients in the non-responders were found to be statistically higher than in the responders. The mean persistence score of the patients in the responders was found to be statistically higher than the non-responders.

Conclusion: Our study shows that some sociodemographic characteristics and TCI dimensions may be associated with early treatment response in MDD patients.

Keywords

• depression
• personality
• temperament and character

Cloninger’in Mizaç ve Karakter Boyutları’nın Depresyon Tedavisi ile İlişkisi

Abstract

Amaç: Bu çalışmada Majör Depresif Bozukluk hastalarında mizaç ve karakter özelliklerinin, 8 haftalık süreçte tedavi yanıtı üzerine etkileri araştırılması, tedaviye yanıt veren ve vermeyen hasta gruplarında mizaç ve karakter özelliklerinin karşılaştırılması amaçlanmıştır.

Materyal ve Metot: Çalışmaya Majör Depresif Bozukluk tanısı konmuş 88 hasta alınmıştır. Hastalara tedaviye başlamadan önce Sosyodemografik Veri Formu, Mizaç ve Karakter Envanteri ve Beck Depresyon Envanteri uygulanmıştır. Tedavinin başlangıcından 8 hafta sonra uygulanan Beck Depresyon Envanteri’ne göre hastalar tedaviye yanıt veren ve vermeyen hastalar şeklinde iki gruba ayrılarak bu iki grubun mizaç ve karakter özellikleri karşılaştırılmıştır.

Bulgular: Hastaların eğitim düzeyi tedaviye yanıt veren grupta daha yüksektir. 2. gruptaki işsiz ve ev hanımı (92,3) hasta sayısı tedaviye yanıt veren gruptaki işsiz ve ev hanımı (%41,3) hasta sayısından daha fazla bulunmuştur. Şiddetli depresyonu olan hasta sayısı tedaviye yanıt vermeyen grupta istatistiksel olarak anlamlı düzeyde daha yüksektir. Tedaviye yanıt vermeyen gruptaki hastaların zarardan kaçınma puanı ortalaması tedaviye yanıt veren gruba göre istatistiksel olarak daha yüksek bulunmuştur. Tedaviye yanıt veren gruptaki hastaların sebat etme puanı ortalaması tedaviye yanıt vermeyen gruba göre istatistiksel olarak daha yüksek bulunmuştur.

Sonuç: Çalışmamız Majör Depresif Bozukluk hastalarında bazı sosyodemografik özelliklerin ve mizaç ve karakter özelliklerinin erken tedavi yanıtı ile ilişkili olabileceğini göstermektedir.

Keywords

• depresyon
• kişilik
• mizaç ve karakter.

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