Interatrial Block and Ventricular Repolarization Parameters in Young Patients with Mild Acute Myocarditis

Abstract

Objective: To evaluate ECG findings regarding interatrial block and ventricular repolarization and certain biochemical parameters in young patients diagnosed as acute myocarditis with normal ventricular functions. Materials and Methods: 405 patients under the age of 35 who underwent diagnostic coronary angiography between January 2014 and January 2020 were retrospectively analyzed. Patients whose ECG records could not be accessed or quality were not suitable for evaluation, with sudden cardiac death, cardiomyopathy, ejection fraction <50%, diabetes mellitus, hypertension, chronic kidney and liver failure were excluded. Patients who underwent diagnostic angiography for the differential diagnosis of acute myocarditis were assigned to myocarditis group (n: 35), and age– and sex–matched subjects with normal coronary circulation and underwent coronary angiography for any other reason were assigned to control group (n: 35). Results: Heart rate, P wave duration, P wave peak time, PR interval, QRS, QT, and Tp–e interval, QTc, Tp–e/QT and Tp–e/QTc ratios did not differ from each other. Whereas troponin (p<0.001), glucose (p=0.004), LDL (p=0.015), AST (p<0.001), ALT (p<0.026), CRP (p<0.001) levels and neutrophil count (p=0.003) were markedly higher in myocarditis group, HDL was lower (p<0.001). Conclusions: Although biochemical parameters display differences in myocarditis group, ECG findings did not differ.

Keywords

• ECG
• myocarditis
• Tp–e interval
• troponin
• ventricular repolarization

Hafif Akut Miyokarditli Genç Hastalarda İnteratriyal Blok ve Ventriküler Repolarizasyon Parametreleri

Abstract

Amaç: Ventrikül fonksiyonları normal olan akut miyokardit tanısı almış genç hastalarda interatriyal blok ve ventriküler repolarizasyon ile ilgili EKG bulgularını ve bazı biyokimyasal parametreleri değerlendirmektir. Materyal ve Metot: Ocak 2014 ile Ocak 2020 arasında tanısal koroner anjiyografi yapılan 35 yaş altı 405 hastanın verileri geriye dönük olarak incelendi. EKG kayıtlarına ulaşılamayan veya kayıt kalitesi değerlendirmeye uygun olmayan, ani kardiyak ölüm, kardiyomiyopati, ejeksiyon fraksiyonu <%50, diabetes mellitus, hipertansiyon, kronik böbrek ve karaciğer yetmezliği olan hastalar çalışma dışı bırakıldı. Akut miyokardit ayırıcı tanısı için tanısal anjiyografi yapılan hastalar miyokardit grubuna (n: 35) ve yaş ve cinsiyet açısından uyumlu, koroner dolaşımı normal olan ve başka bir sebepten ötürü anjiografi yapılan hastalar kontrol grubuna dahil edildi (n: 35). Bulgular: Kalp hızı, P dalgası süresi, P dalgası tepe zamanı, PR aralığı, QRS, QT ve Tp–e aralığı, QTc, Tp–e/QT ve Tp–e/QTc oranları gruplar arasında farklılık göstermedi. Troponin (p<0,001), glukoz (p=0,004), LDL (p=0,015), AST (p<0,001), ALT (p<0,026), CRP (p<0,001) düzeyleri ve nötrofil sayısı (p=0,003) miyokardit grubunda belirgin olarak yüksek iken, HDL daha düşüktü (p<0,001). Sonuç: Biyokimyasal parametreler miyokardit grubunda farklılık göstermsine rağmen, EKG bulguları farklılık göstermedi.

Keywords

• EKG
• miyokardit
• Tp–e aralığı
• troponin
• ventriküler repolarizasy

Supporting Institution

Adıyaman Üniversitesi, Tıp Fakültesi

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