Yaygın Cilt Metastazları: Küçük Hücreli Olabilir mi?

Year 2019, , 112 - 117, 31.03.2019

Timuçin Alar , İsmail Ertuğrul Gedik

https://doi.org/10.26453/otjhs.433606

Abstract

Küçük
hücreli akciğer kanseri (KHAK) nöroendokrin bir tümör olup sıklıkla yaygın
hastalık olarak kendini gösterir. Hastaların çoğunda uzak metastaz vardır ve
başlangıç tedavisi sistemik kemoterapidir. KHAK olan hastalar tedavi almadan
yaşayamazlar ve en önemli faktör hastalığın çabuk tanı almasıdır. Bu yazıda
cilt nodülü eksizyonu ile tanı konan yaygın hastalıklı KHAK’ li bir olgu
sunulmuştur.

Keywords

küçük hücreli, akciğer kanser, cilt metastazı

Widespread Skin Metastases: Could it be Small Cell?

Abstract

Small cell lung cancer (SCLC) is a neuroendocrine
tumor usually presents with disseminated disease. The majority of patients have
distant metastases and initial therapeutic management is systemic chemotherapy.
SCLC patients almost never survive without treatment and most important factor
is than prompt diagnosis of the disease. A case of SCLC with extensive stage
disease that was accurately diagnosed via excised skin nodule is presented in
this report.

Keywords

small cell, lung cancer, skin metastases

References

• 1. Chan BA, Coward JIG. Chemotherapy advances in small-cell lung cancer. J Thorac Dis. 2013;5(S5):S565-S578
• 2. Mollet TW, Garcia CA, Koester G. Skin metastases from lung cancer. Dermatol Online J. 2009;15(5):1.
• 3. Davidson MR, Gazdar AF, Clarke BE. The pivotal role of pathology in the management of lung cancer. J Thorac Dis. 2013;5(S5):S463-S478.
• 4. van Meerbeeck JP, Fennel DA, De Ruysscher DKM. Small-cell lung cancer. Lancet. 2011; 378: 1741–55
• 5. Inoue M, Sawabata N, Okumura M. Surgical intervention for small-cell lung cancer: what is the surgical role? Gen Thorac Cardiovasc Surg. 2012;60:401–5
• 6. Videtic GMM. The Role of Radiation Therapy in Small Cell Lung Cancer. Curr Oncol Rep. 2013;15:405–10
• 7. Jones CD, Cummings IG, Shipolini AR, McCormack DJ. Does surgery improve prognosis in patients with small-cell lung carcinoma? Interact Cardiovasc Thorac Surg. 2013;16:375–80
• 8. Daniels MG, Bowman RV, Yang IA, Govindan R, Fong KM. An emerging place for lung cancer genomics in 2013. J Thorac Dis. 2013;5(S5):S491-S497