Üçüncü Basamak Hastanelerinde Koroner Arter Hastalığı Olan Hastalarda Konvansiyonel Risk Faktörleri Üzerine Çalışma, Pokhara, Nepal

Abstract

Koroner arter hastalığı (KAH) son birkaç yılda gelişmiş dünyada kayda değer bir düşüş göstermiştir, ancak gelişmekte olan dünyada özellikle Güney Asya'da endişe verici bir artış göstermiştir. Bu çalışmanın amacı, dört konvansiyonel risk faktörünü araştırmaktı: Nepal'deki Pokhara vadisinin üçüncü basamak hastanelerinde koroner kalp hastalığı olan hastalarda hipertansiyon, diabetes mellitus, dislipidemi ve sigara kullanımı. Koroner bakım ünitesi (KBU) ve koğuşta çalışmaya kabul edilen KAH olan 100 hasta katıldı. Demografik bilgileri not edildi. Boy, kilo ve kan basıncı standart yöntemlerle kaydedildi. Kan şekeri ve lipit profili, gece boyunca 12 saatlik aç kaldıktan sonra hesaplandı. Risk faktörleri ölçümler, laboratuvar değerleri ve ayrıca aynı hastalık ve geçmiş ilaç öyküsü ile kullanıldı. İstatistiksel analiz için SPSS-16 kullanıldı. Hastaların yaş ortalaması 64,61 ± 11,363, en az 40, en fazla 94 idi. Genel olarak risk faktörleri dağılımı çoktan aza doğru sırası ile sigara içme (% 55), hipertansiyon (% 50), dislipidemi (% 49) ve diabetes mellitus (% 32) idi. Risk faktörlerinin dağılımı 55-69 yaş grubunda en fazla idi. Bu çalışma koroner kalp hastalığı olan hastaların çoğunun konvansiyonel risk faktörlerine sahip olduğunu ve hastalığın gelişiminde büyük rol oynadığını göstermektedir. Değiştirilebilir dört risk faktörünün yanı sıra, aynı zamanda yaş ve cinsiyetin de değiştirilemeyen bu hastalığın önemli katkıları olabileceğini çalışmamız göstermektedir.

Keywords

• Koroner arter hastalığı
• diabetes mellitus
• dislipidemi
• etnisite
• hipertansiyon
• risk faktörleri
• sigara içme

Study on The Conventional Risk Factors in Patients with Coronary Artery Disease in Tertiary Care Hospitals, Pokhara, Nepal

Abstract

Coronary artery disease (CAD) has shown a remarkable decline in the developed world in past few years, but has shown an alarming increase in the developing world especially South Asia. The aim of the study was to investigate four conventional risk factors: Hypertension, diabetes mellitus, dyslipidemia and smoking in patients with coronary heart disease in tertiary care hospitals of Pokhara valley, Nepal. 100 patients with CAD who were admitted in the wards and coronary care unit (CCU) participated in the study. Their demographic information was noted. Height, weight and blood pressure were recorded with standard methods. Blood glucose and lipid profile were estimated after 12 hours of fasting overnight. Risk factors were determined using the measurements, laboratory values and also from the past history of the same illness and medications if any. SPSS-16 was used for statistical analysis. Mean age of the patients was 64.61±11.363 years with minimum age 40 and maximum 94 years. Overall distribution of risk factors in descending order was smoking (55%), hypertension (50%), dyslipidemia (49%) and diabetes mellitus (32%). Distribution of risk factors was maximum in the age group 55-69 years.  This study shows that most of the patients with coronary heart disease have conventional risk factors and they play a major role in the development of the disease. Beside the four modifiable risk factors, our study also shows that age and gender can be major contributors of the disease which can’t be modified.

Keywords

• Coronary artery disease
• diabetes mellitus
• dyslipidemia
• ethnicity
• hypertension
• risk factors
• smoking

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