Allerjik Rinite Benzeyen Semptomlara Sahip Hastaların İnhalan Allerjenlere Karşı Gösterdiği Duyarlılıkta Doğum Ayı Önemli Bir Faktör müdür?

Abstract

İstanbul’un Avrupa bölgesinde gerçekleştirilen retrospektif çalışma ile, allerjik rinit (AR) benzeri semptomları olan hastalarda görülen inhalan allerjen duyarlılığı ile kişilerin doğum ayları arasında bir ilişki olup olmadığını araştırmak amaçlanmıştır. AR’ye benzeyen semptomlar gösteren 3460 hastaya deri prik test uygulanmıştır. Çalışmada kullanılan alerjenler kökenlerine göre bitkiler, mantarlar, ev tozu akarları ve hayvan epiteli (kedi ve köpek) olmak üzere 4 ana kategoride gruplandırılmıştır. Sonuçlar inhalan allerjenler bakımından SPSS analiz yazılımı kullanılarak retrospektif olarak değerlendirilmiştir. 2302 hastanın (%66,5) yaygın inhalan allerjenlerden en az bir veya daha fazlasına karşı duyarlılık gösterdiği belirlendi. Polen duyarlılığı en yüksek oranda (%53,8) görülürken en az rastlanan duyarlılık (%21,7) hayvan epiteline karşı elde edildi. Haziran ve Temmuz ayında doğanların toz akarlarına karşı duyarlılık gösterme olasılığının arttığı (p<0,012) buna karşılık, Ağustos ayında doğan bireylerin Quercus Robur’a karşı duyarlı olma olasılıklarının daha düşük olduğu (p<0,038) bulundu. Yaz dönemlerinde doğan hastaların ev tozu akarlarına (HDM) karşı duyarlılık gösterme olasılığının yüksek olduğu görülmüştür. Ev tozu akarlarına karşı evlerde mücadele edilerek olabildiğince alt seviyede tutmak önemlidir. Bu kapsamda elde ettiğimiz bulgular, AR’ye benzeyen semptomlara sahip hastalar için kişiselleştirilmiş koruyucu sağlık hizmetlerinin planlanmasına katkı sunabilir.

Keywords

• Deri prick testi,Allerjik rinit,İnhalant allerjen,Doğum Ayı

Is month of birth an important factor for sensitization to inhalant allergens in patients with symptoms similar to Allergic Rhinitis?

Abstract

In this retrospective study, performed in the European region of Istanbul, it was aimed to investigate whether the birth month is a factor in inhalant allergen sensitivity in patients with symptoms similar to allergic rhinitis (AR). Skin prick test was applied to 3460 patients with symptoms similar to AR. The allergens used in the study were grouped according to their origin in four main categories: plants, fungi, house dust mites and animal epithelium (cat and dog). The results were retrospectively evaluated using SPSS analysis software. 2302 patients (66.5%) had at least one or more sensitization to the common inhalant allergens. Pollen sensitization was found to be the most common (53.8%) while sensitivity to the animal dander was the lowest (21.7%) among the individuals. Birth in June and July increased the risk for developing sensitization to the house dust mite (p< 0.012) whereas, birth in August was correlated with a lower risk of sensitization to Quercus Robur (p< 0.038).  This study showed that individuals born in summer period can be at risk for developing HDM sensitizations. Thus, it is important to keep the house dust mites as low as possible by taking preventative measures in houses. Our findings may contribute to the planning of personalized preventive health care services for patients with AR-like symptoms.

Keywords

• Skin prick test,allergic rhinitis,inhalant allergens,birth of month

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