Akut ve Kronik Ürtiker Hastalarında Platelet Belirteçlerinin, C-Reaktif Protein Düzeyleri ve Hastalık Şiddeti ile Karşılaştırılması

Year 2019, Volume: 4 Issue: 1, 57 - 67, 31.03.2019

Derya Yaşar Serpil Şener , Gülbahar Saraç

https://doi.org/10.26453/otjhs.458544

Abstract

Bu çalışmada; akut ve kronik ürtikerli hastalarda, platelet
belirteçlerini ve C-reaktif protein düzeyleri ölçülmüştür. Ürtiker
patogenezinde plateletlerin rolünü araştırmak amaçlandı. Çalışmaya 18-76 yaş
arasında 34 akut ürtiker hastası, 27 kronik ürtiker hastası ve 30 sağlıklı
gönüllü alınmıştır. Gruplar arasında demografik veriler açısından anlamlı fark
saptanmamıştır. Platelet belirteçlerinden MPV ve PDW değerlerinde akut ürtiker
ve kronik ürtiker grubu arasında fark saptanmaz iken, kontrol grubunda bu
değerler istatistiksel olarak anlamlı yüksek bulundu (p<0,001).  Kontrol grubunda CRP değeri istatistiksel
olarak anlamlı düşük bulundu (p:0,008). Ürtiker patogenezinde plateletlerin
rolünün daha iyi anlaşılması için geniş hasta serilerinde çalışmalara
gereksinim vardır.

Keywords

ürtiker, c-reaktif protein, kronik ürtiker, akut ürtiker

Comparison of Platelet Markers with C-Reactive Protein Levels and Disease Severity at Patients with Acute and Chronic Urticaria

Abstract

In this study; Platelet markers and C-reactive protein
levels were measured in patients with acute and chronic urticaria. The aim of
this study was to investigate the role of platelets in the pathogenesis of
urticaria.  The study included 34 acute
urticaria patients, 27 chronic urticaria patients and 30 healthy volunteers
between the ages of 18-76. There was no significant difference between the
groups in terms of demographic data. MPV and PDW values of platelet markers
were not significantly different between acute urticaria and chronic urticaria
group (p<0.001). CRP values were significantly lower in the control group
(p:0.008). In order to better understand the role of platelets in the
pathogenesis of urticaria, large series of patients are needed.

Keywords

urticaria, platelets, C-reactive protein, Chronic Urticaria

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