Does Phototherapy Influence Alpha Melanocyte Stimulating Hormone Levels?

Year 2021, Volume: 6 Issue: 2, 201 - 206, 05.06.2021

Meltem Karabay , Erdem Çokluk

https://doi.org/10.26453/otjhs.881968

Abstract

Objective: We aimed to investigate the effect of phototherapy on plasma alpha-melanocyte-stimulating hormone (α-MSH) levels of newborns with indirect hyperbilirubinemia (IHB) for the first time.
Materials and Methods: A total of 45 cases, who were hospitalized in neonatal intensive care units between July 1, 2019, to September 30, 2019, and received phototherapy, were retrospectively included in the study. Plasma α-MSH and bilirubin levels were measured before and after the phototherapy.
Results: A total of 45 newborns (19 girls and 26 boys) were included in to study. The average birth weight was 3202 grams and the mean total bilirubin level was 17.2 mg/dL. α-MSH levels before and after phototherapy were 326.2 (4.0-2228.0) ng/L and 373.9 (8.7-2283.0) ng/L, respectively and did not represent a significant difference (p>0.05).
Conclusion: This study demonstrated that there was no effect between phototherapy applied for newborn IHB and plasma α-MSH levels.

Keywords

Alpha-melanocyte stimulating hormone, phototherapy, newborn, indirect hyperbilirubinemia

Supporting Institution

yok

Project Number

yok

Thanks

The authors would like to thank İbrahim Caner, Serpil Çakır Çetin, as well as NICU workers for their contributions.

Fototerapi Alfa Melanosit Uyarıcı Hormon Seviyelerini Etkiler mi?

Abstract

Amaç: İlk kez bu araştırmayla indirekt hiperbilirubinemi (İHB) olan yenidoğanlarda fototerapinin plazma alfa-melanosit uyarıcı hormon (α-MSH) üzerine etkisinin araştırılması amaçlanmıştır.
Materyal ve Metot: İHB nedeniyle yenidoğan yoğun bakım ünitesinde yatarak fototerapi tedavisi uygulanan 45 olgu, 1 Temmuz 2019-30 Eylül 2019 tarihleri arasında prospektif olarak çalışmaya dahil edildi. Fototerapi öncesi ve sonrası plazma α-MSH ve bilirubin düzeyleri ölçüldü.
Bulgular: Çalışmaya 45 yenidoğan (19 kız, 26 erkek) dahil edildi. Ortalama doğum kilosu 3202 gr ve ortalama total bilirubin düzeyi 17,2 mg /dl idi. Fototerapi öncesi ve sonrası α-MSH seviyeleri sırasıyla 326,2 (4,0-2228,0) ng/L ve 373,9 (8,7-2283,0) ng/L olup benzerdi (p> 0,05).
Sonuç: Bu çalışmayla İHB için yenidoğanlara uygulanan fototerapinin, plazma α-MSH üzerine etkisi olmadığı saptanmıştır.

Keywords

Alfa-melanosit uyarıcı hormon, indirekt hiperbilirubinemi, fototerapi, yenidoğan

Project Number

yok

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