Primary antiphospholipid syndrome patient associated with refractory thrombocytopenia and Factor V Leiden mutation treated with eltrombopag

Volume: 10 Number: 1 April 1, 2017
Sinem Namdaroğlu , Şerife Solmaz Medeni , Tuğba Çetintepe , Ozan Barış Namdaroğlu , Oktay Bilgir
EN TR

Primary antiphospholipid syndrome patient associated with refractory thrombocytopenia and Factor V Leiden mutation treated with eltrombopag

Abstract

Antiphospholipid antibody syndrome (APS) is a systemic autoimmune disorder characterized by recurrent arterial or venous thrombosis, fetal loss, thrombocytopenia, neurological symptoms and presence of serum antiphospholipid antibodies (AFA). In this report,we present a young male patient with thrombocytopenia who was refractory to steroids, intravenous immunoglobulin and splenectomy but had complete response to eltrombopag treatment, FV Leiden heterozygous mutant positive, also had a history of sinüs thrombosis taking oral anticoagulant treatment has been diagnosed primary APS. Eltrombopag treatment primary antiphospholipid syndrome patient associated with refractory thrombocytopenia.

Keywords

Eltrombopag, Primary antiphospholipid syndrome, Thrombocytopenia, Factor V Leiden

References

  1. No references found
APA
Namdaroğlu, S., Medeni, Ş. S., Çetintepe, T., Namdaroğlu, O. B., & Bilgir, O. (2017). Primary antiphospholipid syndrome patient associated with refractory thrombocytopenia and Factor V Leiden mutation treated with eltrombopag. Pamukkale Medical Journal, 10(1), 67-72. https://izlik.org/JA77UN57PT
AMA
1.Namdaroğlu S, Medeni ŞS, Çetintepe T, Namdaroğlu OB, Bilgir O. Primary antiphospholipid syndrome patient associated with refractory thrombocytopenia and Factor V Leiden mutation treated with eltrombopag. Pam Med J. 2017;10(1):67-72. https://izlik.org/JA77UN57PT
Chicago
Namdaroğlu, Sinem, Şerife Solmaz Medeni, Tuğba Çetintepe, Ozan Barış Namdaroğlu, and Oktay Bilgir. 2017. “Primary Antiphospholipid Syndrome Patient Associated With Refractory Thrombocytopenia and Factor V Leiden Mutation Treated With Eltrombopag”. Pamukkale Medical Journal 10 (1): 67-72. https://izlik.org/JA77UN57PT.
EndNote
Namdaroğlu S, Medeni ŞS, Çetintepe T, Namdaroğlu OB, Bilgir O (April 1, 2017) Primary antiphospholipid syndrome patient associated with refractory thrombocytopenia and Factor V Leiden mutation treated with eltrombopag. Pamukkale Medical Journal 10 1 67–72.
IEEE
[1]S. Namdaroğlu, Ş. S. Medeni, T. Çetintepe, O. B. Namdaroğlu, and O. Bilgir, “Primary antiphospholipid syndrome patient associated with refractory thrombocytopenia and Factor V Leiden mutation treated with eltrombopag”, Pam Med J, vol. 10, no. 1, pp. 67–72, Apr. 2017, [Online]. Available: https://izlik.org/JA77UN57PT
ISNAD
Namdaroğlu, Sinem - Medeni, Şerife Solmaz - Çetintepe, Tuğba - Namdaroğlu, Ozan Barış - Bilgir, Oktay. “Primary Antiphospholipid Syndrome Patient Associated With Refractory Thrombocytopenia and Factor V Leiden Mutation Treated With Eltrombopag”. Pamukkale Medical Journal 10/1 (April 1, 2017): 67-72. https://izlik.org/JA77UN57PT.
JAMA
1.Namdaroğlu S, Medeni ŞS, Çetintepe T, Namdaroğlu OB, Bilgir O. Primary antiphospholipid syndrome patient associated with refractory thrombocytopenia and Factor V Leiden mutation treated with eltrombopag. Pam Med J. 2017;10:67–72.
MLA
Namdaroğlu, Sinem, et al. “Primary Antiphospholipid Syndrome Patient Associated With Refractory Thrombocytopenia and Factor V Leiden Mutation Treated With Eltrombopag”. Pamukkale Medical Journal, vol. 10, no. 1, Apr. 2017, pp. 67-72, https://izlik.org/JA77UN57PT.
Vancouver
1.Sinem Namdaroğlu, Şerife Solmaz Medeni, Tuğba Çetintepe, Ozan Barış Namdaroğlu, Oktay Bilgir. Primary antiphospholipid syndrome patient associated with refractory thrombocytopenia and Factor V Leiden mutation treated with eltrombopag. Pam Med J [Internet]. 2017 Apr. 1;10(1):67-72. Available from: https://izlik.org/JA77UN57PT