Refrakter trombositopeni ile seyreden Faktör V Leiden mutasyonu olan primer antifosfolipid sendromlu olguda eltrombopag deneyimi

Cilt: 10 Sayı: 1 1 Nisan 2017
Sinem Namdaroğlu , Şerife Solmaz Medeni , Tuğba Çetintepe , Ozan Barış Namdaroğlu , Oktay Bilgir
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Primary antiphospholipid syndrome patient associated with refractory thrombocytopenia and Factor V Leiden mutation treated with eltrombopag

Öz

Antiphospholipid antibody syndrome (APS) is a systemic autoimmune disorder characterized by recurrent arterial or venous thrombosis, fetal loss, thrombocytopenia, neurological symptoms and presence of serum antiphospholipid antibodies (AFA). In this report,we present a young male patient with thrombocytopenia who was refractory to steroids, intravenous immunoglobulin and splenectomy but had complete response to eltrombopag treatment, FV Leiden heterozygous mutant positive, also had a history of sinüs thrombosis taking oral anticoagulant treatment has been diagnosed primary APS. Eltrombopag treatment primary antiphospholipid syndrome patient associated with refractory thrombocytopenia.

Anahtar Kelimeler

Eltrombopag, Primary antiphospholipid syndrome, Thrombocytopenia, Factor V Leiden

Kaynakça

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Kaynak Göster

APA
Namdaroğlu, S., Medeni, Ş. S., Çetintepe, T., Namdaroğlu, O. B., & Bilgir, O. (2017). Primary antiphospholipid syndrome patient associated with refractory thrombocytopenia and Factor V Leiden mutation treated with eltrombopag. Pamukkale Medical Journal, 10(1), 67-72. https://izlik.org/JA77UN57PT
AMA
1.Namdaroğlu S, Medeni ŞS, Çetintepe T, Namdaroğlu OB, Bilgir O. Primary antiphospholipid syndrome patient associated with refractory thrombocytopenia and Factor V Leiden mutation treated with eltrombopag. Pam Tıp Derg. 2017;10(1):67-72. https://izlik.org/JA77UN57PT
Chicago
Namdaroğlu, Sinem, Şerife Solmaz Medeni, Tuğba Çetintepe, Ozan Barış Namdaroğlu, ve Oktay Bilgir. 2017. “Primary antiphospholipid syndrome patient associated with refractory thrombocytopenia and Factor V Leiden mutation treated with eltrombopag”. Pamukkale Medical Journal 10 (1): 67-72. https://izlik.org/JA77UN57PT.
EndNote
Namdaroğlu S, Medeni ŞS, Çetintepe T, Namdaroğlu OB, Bilgir O (01 Nisan 2017) Primary antiphospholipid syndrome patient associated with refractory thrombocytopenia and Factor V Leiden mutation treated with eltrombopag. Pamukkale Medical Journal 10 1 67–72.
IEEE
[1]S. Namdaroğlu, Ş. S. Medeni, T. Çetintepe, O. B. Namdaroğlu, ve O. Bilgir, “Primary antiphospholipid syndrome patient associated with refractory thrombocytopenia and Factor V Leiden mutation treated with eltrombopag”, Pam Tıp Derg, c. 10, sy 1, ss. 67–72, Nis. 2017, [çevrimiçi]. Erişim adresi: https://izlik.org/JA77UN57PT
ISNAD
Namdaroğlu, Sinem - Medeni, Şerife Solmaz - Çetintepe, Tuğba - Namdaroğlu, Ozan Barış - Bilgir, Oktay. “Primary antiphospholipid syndrome patient associated with refractory thrombocytopenia and Factor V Leiden mutation treated with eltrombopag”. Pamukkale Medical Journal 10/1 (01 Nisan 2017): 67-72. https://izlik.org/JA77UN57PT.
JAMA
1.Namdaroğlu S, Medeni ŞS, Çetintepe T, Namdaroğlu OB, Bilgir O. Primary antiphospholipid syndrome patient associated with refractory thrombocytopenia and Factor V Leiden mutation treated with eltrombopag. Pam Tıp Derg. 2017;10:67–72.
MLA
Namdaroğlu, Sinem, vd. “Primary antiphospholipid syndrome patient associated with refractory thrombocytopenia and Factor V Leiden mutation treated with eltrombopag”. Pamukkale Medical Journal, c. 10, sy 1, Nisan 2017, ss. 67-72, https://izlik.org/JA77UN57PT.
Vancouver
1.Sinem Namdaroğlu, Şerife Solmaz Medeni, Tuğba Çetintepe, Ozan Barış Namdaroğlu, Oktay Bilgir. Primary antiphospholipid syndrome patient associated with refractory thrombocytopenia and Factor V Leiden mutation treated with eltrombopag. Pam Tıp Derg [Internet]. 01 Nisan 2017;10(1):67-72. Erişim adresi: https://izlik.org/JA77UN57PT