Myocardial performance index is associated with Systematic Coronary Risk Estimation (SCORE) system in chronic coronary syndrome
Abstract
Objective: The Systematic Coronary Risk Estimation (SCORE) system is used to determine 10-year cardiovascular risk. Myocardial performance index (MPI), a well-accepted echocardiographic parameter, is used to provide an information about global function of the ventricle. We aimed to investigate the relationship between MPI and SCORE.
Methods: A total of 168 participants with chronic coronary syndrome (CCS) presented to cardiology outpatient clinic between 1 June and 31 December 2020 were retrospectively enrolled in the study. Cardiovascular risk estimation was calculated by SCORE assessment. The participants were divided into two groups as 46 patients with low cardiovascular risk, and 122 patients with moderate-high-very high risk, according to the SCORE. Laboratory parameters and echocardiography findings of the patients were recorded.
Results: There was no difference in body mass index, office systolic, and diastolic blood pressure between the groups. While blood glucose was 94.5 (83.0-110.3) in the low-risk group, it was 101.0 (90.0-130.5) in the moderate-high risk patient group (p = 0.007). Similarly, Urea, creatinine, lactate dehydrogenase, total cholesterol, NT pro-BNP, and Troponin T in the moderate-high risk group were significantly higher than was the low-risk group. MPI was significantly higher in the moderate-high risk patient group (p <0.001). MPI (OR = 2.358, 95 % CI: 1.033-5.382, p = 0.042), urea (OR = 1.090, 95 % CI: 1.019-1.166, p = 0.012), and glucose (OR = 1.023, 95 % CI: 1.003-1.043, p = 0.025) were independently associated with the moderate-high SCORE.
Conclusion: We found that MPI predicted moderate-high SCORE system. Further studies are warranted to better clarify the association of SCORE with echocardiographic parameters including MPI.
Keywords
myocardial performance index, Systematic Coronary Risk Estimation (SCORE) system, chronic coronary syndrome, cardiovascular risk
References
- 1. Townsend N, Nichols M, Scarborough P, Rayner M. Cardiovascular disease in Europe 2015: epidemiological update. Eur Heart J 2015;36:2696–2705. https://doi.org/10.1093/eurheartj/ehv428.
- 2. Conroy RM, Pyorala K, Fitzgerald AP, et al. Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. Eur Heart J 2003;24:987–1003. https://doi.org/10.1016/s0195-668x(03)00114-3.
- 3. Lewington S, Clarke R, Qizilbash N, Peto R, Collins R. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 2002;360:1903–1913. https://doi.org/10.1016/s0140-6736(02)11911-8.
- 4. Neaton JD, Blackburn H, Jacobs D, et al. Serum cholesterol level mortality findings for men screened in the Multiple Risk Factor Intervention Trial. Multiple Risk Factor Intervention Trial Research Group. Arch Intern Med 1992;152:1490–1500.
- 5. Prescott E, Hippe M, Schnohr P, Hein HO, Vestbo J. Smoking and risk of myocardial infarction in women and men: longitudinal population study. BMJ 1998;316:1043–1047. https://doi.org/10.1136/bmj.316.7137.1043.
- 6. Jousilahti P, Vartiainen E, Tuomilehto J, Puska P. Sex, age, cardiovascular risk factors, and coronary heart disease: a prospective follow-up study of 14 786 middle-aged men and women in Finland. Circulation 1999;99:1165–1172. https://doi.org/10.1161/01.cir.99.9.1165.
- 7. Piepoli MF, Hoes AW, Agewall S, et al. 2016 European Guidelines on cardiovascular disease prevention in clinical practice: The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts)Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR). Eur Heart J 2016;37:2315-2381. https://doi.org/10.1093/eurheartj/ehw106.
- 8. Tei C, Nishimura RA, Seward JB et al. Noninvasive Doppler-derived myocardial performance index: correlation with simultaneous measurements of cardiac catheterization measurements. J Am Soc Echocardiogr 1997;10:169–178. https://doi.org/10.1016/s0894-7317(97)70090-7.
- 9. Arnlöv J, Ingelsson E, Risérus U, Andrén B, Lind L. Myocardial performance index, a Doppler-derived index of global left ventricular function, predicts congestive heart failure in elderly men. Eur Heart J 2004;25:2220-5. https://doi.org/10.1016/j.ehj.2004.10.021.
- 10. Masugata H, Senda S, Goda F, et al. Independent determinants of the Tei index in hypertensive patients with preserved left ventricular systolic function. Int Heart J. 2009;50:331–340. https://doi.org/10.1536/ihj.50.331.
