Effect of dexpanthenol on patient comfort in treatment of traumatic corneal abrasions

Year 2021, Volume: 14 Issue: 1, 43 - 48, 04.01.2021

Deniz Kılıc , Esra Vural Gamze Albayrak Mahmut Arslan

https://doi.org/10.31362/patd.730487

Abstract

Objective: The aim in this study was to investigate if the use of Dexpanthenol could play a role in the relief of pain in the treatment of corneal abrasions (CA).
Methods: Patients presenting to the BLINDED with a diagnosis of CA were conducted in this retrospective, case-control study. A detailed ocular examination was done and pain severity was assessed using a visual analogue scale (VAS) score. In group 1, subjects were treated with only topical ofloxacin %0.3 while subjects in group 2 were treated with topical ofloxacin %0.3 and dexpanthenol. Foreign body sensation, photophobia, excessive lacrimation and VAS were documented at follow up examinations.
Results: 70 patients were allocated into group 1 and 68 patients were allocated into group 2. At each visit, there were significant differences in VAS scores between the groups (p<0.005). VAS scores were lower in group-2. There were no statistically significant differences between two groups in terms of photophobia, foreign body sensation, excessive lacrimation (p>0.05). All patients were free of any complications.
Conclusion: Although it was shown that adding topical dexpanthenol to the treatment regimen could permit faster pain relief in treating CAs, the prospective studies should be done.
Key words: Traumatic corneal abrasion, Dexpanthenol, Visual analogue scale.

Keywords

Traumatic corneal abrasion, Dexpanthenol, Visual analogue scale

Travmatik korneal abrazyon hastalarında dekspantenol kullanımının hasta konforuna olan etkisi

Abstract

Amaç: Bu çalışmada amaç, Dekspantenol kullanımının travmatik kornea abrazyonlarının (KA) tedavisinde ağrının giderilmesinde etkili olabileceğini araştırmaktır.
Yöntemler: Bu retrospektif, vaka kontrol çalışması KA tanısı ile KARARTILDI başvuran hastalar seçilerek yapıldı. Ayrıntılı oküler muayene yapıldı ve ağrı şiddeti görsel analog skala (GAS) skoru ile değerlendirildi. 1.grup sadece topikal ofloksasin% 0.3 ile tedavi edilirken, grup 2'deki hastalar topikal ofloksasin% 0.3 ve dekspantenol ile tedavi edildi. Takip muayenelerinde yabancı cisim hissi, fotofobi, aşırı lakrimasyon ve GAS kaydedildi.
Bulgular: 70 hasta ilk grupta yeralırken, ikinci grupta 68 hasta vardı. Tüm vizitlerde GAS anlamlı olarak düşük bulundu.(p <0.001). İki grup arasında fotofobi, yabancı cisim hissi, aşırı lakrimasyon açısından istatistiksel olarak anlamlı fark yoktu (p>0.05).
Sonuç: KA tedavisinde Dekspantenol eklemek ağrının azaltılmasında rol oynadığı gösterilmiş olsa da, bulguların prospektif çalışmalarla desteklenmesi gerekmektedir.
Anahtar kelimeler: Travmatik korneal abrazyon, Dekspantenol, görsel ağrı skalası

Keywords

Travmatik korneal abrazyon, Dekspantenol, görsel ağrı skalası

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