İnaktive Poliovirüs ve Oral Poliovirüs Aşılarının Karşılaştırılması

Year 2013, Volume: 11 Issue: 1, 1 - 5, 01.06.2013

Hüseyin Anıl Korkmaz Adem Aydın Belgin Ünal

https://doi.org/10.4274/Jcp.11.01

Abstract

Giriş: Bu çalışmada inaktive poliovirüs aşısı İPV ve oral poliovirüs OPV aşılarının uygulandıkları 2., 4., 6. ve 18. aylarda oluşturdukları sistemik yan etkiler ve ateş reaksiyonları açısından karşılaştırılması amaçlanmıştır.Gereç ve Yöntem: Çalışma grubunu 2003 ile 2008 yılları arasında 2, 4, 6 ve 18 aylıkken İPV ve OPV uygulandıktan sonra değerlendirilen 1634 sütçocuğu oluşturmuştur. Tüm aileler çocuklarında oluşan sistemik ve ateş reaksiyonları ile ilgili yan etkileri araştırmacıya bildirmiştir.Bulgular: OPV uygulanmasından sonra oluşan sistemik ve ateş reaksiyonları İPV’ye göre anlamlı derecede yüksek bulundu sırasıyla %2,33’e karşılık %1,12 ve %5,2’ye karşılık %2,8; p

Keywords

İnaktive poliovirüs aşısı, oral poliovirüs aşısı, aşılar, süt çocukları, yan ekiler

Comparison of Inactivated and Oral Poliovirus Vaccines

Abstract

In tro duc ti on: The aim of this study was to compare the rates of systemic and fever reactions of inactivated poliovirus vaccine IPV and oral poliovirus vaccine OPV at 2, 4, 6 and 18 months of age.Materials and Methods: The study population was made up of 1634 infants at 2, 4, 6, and 18 months of age who had received IPV and OPV vaccines between 2003 and 2008. All parents reported systemic and fever adverse events to the investigator.Results: Systemic and fever reactions were more commonly observed in infants received OPV vaccines than those received IPV vaccines 2.33% vs. 1.12% and 5.2% vs. 2.8%; p

Keywords

Inactivated poliovirus vaccine, oral poliovirus vaccine, vaccines, infants, adverse events

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