Clinical Outcomes of Acute Renal Failure in Children

Osman Dönmez; Oğuzhan Durmaz

Clinical Outcomes of Acute Renal Failure in Children

Year 2009, Volume: 7 Issue: 3, 57 - 61, 01.12.2009

Abstract

Amaç: Bu çalıﬂmanın amacı, hastaneye yatırılan çocuklarda akut böbrekyetmezliğinin ABY klinik progresyonu, tedavisini ve etyolojik faktörlerininaraﬂtırılmasıdır. Gereç ve Yöntem: Uludağ Üniversitesi Tıp Fakültesi çocuk yoğun bakım ve hastanenin diğer yoğun bakım ünitelerinde Ocak 2005 ile Ağustos 2006 tarihleri arasındaABY tanısı konmuﬂ 1 ay ile 18 yaﬂ arasında 63 hastanın dosyaları retrospektif olarakincelendi. Bulgular: Çalıﬂmaya alınan hastaların 42’si erkek, 21’i kız olup, ortalama yaﬂ5,4±5,3 yıl idi. Yoğun bakım ünitesine yatırılan hastaların %4,9’unda ABY saptanmıﬂtır. ABY’nin etyolojisinde sepsis %23,8 oranı ile en sık etyolojik faktör olaraksaptandı. Bunu sırasıyla, gastroenteritler %19,1 , tümör lisis sendromu %17,4 vekalp cerrahisi %15,9 sonrası geliﬂen ABY izlemiﬂtir. Oligüri, sepsis, hiperpotasemi, asidoz ve diyaliz yapılması artmıﬂ mortalite oranı ile iliﬂkili bulundu p

Keywords

Akut böbrek yetmezliği, çocuk, diyaliz, prognoz

References

1. Vogt BA, Avner ED. Acute renal Failure. In: Behrman RE, Kliegman PM, Jenson HB (eds) Nelson textbook of pediatrics 17th edn. Saunders, Philadelphia States of America, 2004;1767-71.
2. Siegel NJ, Van WSK, Devarajan P. Pathogenesis of acute renal failure. In: Avner ED, Harmon WE, Niaudet P (eds). Pediatric Nephrology 5th ed. Philadelphia, Lippincott Williams&Wilkins, 2004;1225-51.
3. Bunchman TE, Barletta MG. Acute renal failure in Children and infants. Curr Opp Crit Care 2004;10:499-504.
4. Thadhani R, Pascual M, Bonvertre VJ. Acute renal failure. N Engl J Med 1996;334:1448-60.
5. Otukesh H, Hoseini R, Hooman N, Chalian M, Chalian H, Tabrroki A. Prognosis of acute renal failure in children. Pediatr Nephrol 2006;21:1873-8.
6. Ozalt›n F, Yalc›n B, Orhan D, Sari N, Caglar M, Besbas N et al. A. An unusual Cause of acute renal failure: renal lymhoma. Pediatr Nephrol 2004;19:912-4.
7. Anochie IC, Eke FU. Acute renal failure in Nigerian children: Port Harcourt experience. Pediatr Nephrol 2005;20:1610-4.
8. Filler G. Acute renal Failure in Children: etiology and management. Pediatr Drugs 2001;3:783-92.
9. Radhakrisnan J, Kiryluk K. Acute renal failure outcome in Children and adults. Kidney Int 2006;69:17-9.
10. Bunchman TE, McBryde KD, Mottes TE Gardner JJ, Maxvold NJ, Brophy PD. Pediatric acute renal failure: outcome by modality and disease. Pediatr Nephrol 2001; 16:1067-71.
11. Moghal NE, Brocklebank JT, Maedow RS. A review of acute renal failure in children: incidence, etiology and outcome. Clin Nephrol 1998;49:91-5.
12. Schwartz Gj, Haycock GB, Edelmann CM . A Simple Estimate of Glomerular Filtration Rate in Children Derived From Body Length and Plasma Creatinine. Pediatrics 1976;58:259-63.
13. Schrier RW, Wang W, Poole B, Mitra A. Acute renal failure: definitions, diagnosis, pathogenesis, and therapy. J Clin Invest 2004;114:5-14.
14. Gunn VL, Nechyba C. The Harriet Lane Handbook, 16th edn. Mosby, St Louis, 2002:3-17.
15. Hui-Stickle S, Brewer ED, Goldstein SL. Pediatric ARF epidemiology at a tertiary care center from 1999 to 2001. Am J Kidney Dis 2005;45:96-101.
16. Bailey D, Phan V, Litalien C, Ducruet T, Merouani A, Lacroix J, Gauvin. Risk factors of acute renal failure in critically ill children: A prospective descriptive epidemiological study. Pediatr Crit Care Med 2007;8:29-35.
17. Andreoli SP: Acute renal failure. Curr Opin Pediatr 2002;14:183-8.
18. Strazdins V, Watson AR, Harvey B. Renal replacement therapy for acute renal failure in children: Europen Guidelines. Pediatr Nephrol 2004;19:199-207.
19. Loza R, Estremadoyro L, Loza C, Cieza J. Factors associated with mortality in acute renal failure (ARF) in children. Pediatr Nephrol 2006;21:106-9.
20. Akcan-Arikan A, Zappitelli M, Loftis LL, Washburn KK, Jefferson LS, Goldstein SL Modified RIFLE criteria in critically ill children with acute kidney injury. Kidney Int 2007;71:1028-35.
21. Vachvanichsanong P, Dissaneewate P, Lim A, McNeil E. Childhood Acute Renal Failure: 22-Year Experience in a University Hospital in Southern Thailand. Pediatrics 2006;118:786-91.
22. Flynn JT. Choice of dialysis modality for management of pediatric acute renal failure. Pediatr Nephrol 2002;17:61-9.

Clinical Outcomes of Acute Renal Failure in Children

Year 2009, Volume: 7 Issue: 3, 57 - 61, 01.12.2009

Osman Dönmez Oğuzhan Durmaz

Abstract

Aim: The aim of this study was to investigate the etiological factors, clinical progression and management of acute renal failure ARF in hospitalized children. Materials and Method: Medical records of 63 patients aged between 1 month and18 years who were hospitalized at Uludag University, Department of Pediatrics or atvarious intensive care departments of the faculty and diagnosed with ARF betweenJanuary 2005 and August 2006 were retrospectively analyzed. Results: Forty two of study patients were male and 21 were female. Mean agewas 5.4±5.3 years. ARF was found in 4.9% of all hospitalized patients. Sepsis wasthe most frequent etiological factor with a ratio of 23.8%; which was followed bygastroenteritis 19.1% , tumor lysis syndrome 17.4% and cardiac surgery 15.9% . Oliguria, sepsis, hyperkalemia, acidosis and dialysis were found to be associated with increased mortality p

Keywords

Acute renal failure, children, dialysis, prognosis

References

1. Vogt BA, Avner ED. Acute renal Failure. In: Behrman RE, Kliegman PM, Jenson HB (eds) Nelson textbook of pediatrics 17th edn. Saunders, Philadelphia States of America, 2004;1767-71.
2. Siegel NJ, Van WSK, Devarajan P. Pathogenesis of acute renal failure. In: Avner ED, Harmon WE, Niaudet P (eds). Pediatric Nephrology 5th ed. Philadelphia, Lippincott Williams&Wilkins, 2004;1225-51.
3. Bunchman TE, Barletta MG. Acute renal failure in Children and infants. Curr Opp Crit Care 2004;10:499-504.
4. Thadhani R, Pascual M, Bonvertre VJ. Acute renal failure. N Engl J Med 1996;334:1448-60.
5. Otukesh H, Hoseini R, Hooman N, Chalian M, Chalian H, Tabrroki A. Prognosis of acute renal failure in children. Pediatr Nephrol 2006;21:1873-8.
6. Ozalt›n F, Yalc›n B, Orhan D, Sari N, Caglar M, Besbas N et al. A. An unusual Cause of acute renal failure: renal lymhoma. Pediatr Nephrol 2004;19:912-4.
7. Anochie IC, Eke FU. Acute renal failure in Nigerian children: Port Harcourt experience. Pediatr Nephrol 2005;20:1610-4.
8. Filler G. Acute renal Failure in Children: etiology and management. Pediatr Drugs 2001;3:783-92.
9. Radhakrisnan J, Kiryluk K. Acute renal failure outcome in Children and adults. Kidney Int 2006;69:17-9.
10. Bunchman TE, McBryde KD, Mottes TE Gardner JJ, Maxvold NJ, Brophy PD. Pediatric acute renal failure: outcome by modality and disease. Pediatr Nephrol 2001; 16:1067-71.
11. Moghal NE, Brocklebank JT, Maedow RS. A review of acute renal failure in children: incidence, etiology and outcome. Clin Nephrol 1998;49:91-5.
12. Schwartz Gj, Haycock GB, Edelmann CM . A Simple Estimate of Glomerular Filtration Rate in Children Derived From Body Length and Plasma Creatinine. Pediatrics 1976;58:259-63.
13. Schrier RW, Wang W, Poole B, Mitra A. Acute renal failure: definitions, diagnosis, pathogenesis, and therapy. J Clin Invest 2004;114:5-14.
14. Gunn VL, Nechyba C. The Harriet Lane Handbook, 16th edn. Mosby, St Louis, 2002:3-17.
15. Hui-Stickle S, Brewer ED, Goldstein SL. Pediatric ARF epidemiology at a tertiary care center from 1999 to 2001. Am J Kidney Dis 2005;45:96-101.
16. Bailey D, Phan V, Litalien C, Ducruet T, Merouani A, Lacroix J, Gauvin. Risk factors of acute renal failure in critically ill children: A prospective descriptive epidemiological study. Pediatr Crit Care Med 2007;8:29-35.
17. Andreoli SP: Acute renal failure. Curr Opin Pediatr 2002;14:183-8.
18. Strazdins V, Watson AR, Harvey B. Renal replacement therapy for acute renal failure in children: Europen Guidelines. Pediatr Nephrol 2004;19:199-207.
19. Loza R, Estremadoyro L, Loza C, Cieza J. Factors associated with mortality in acute renal failure (ARF) in children. Pediatr Nephrol 2006;21:106-9.
20. Akcan-Arikan A, Zappitelli M, Loftis LL, Washburn KK, Jefferson LS, Goldstein SL Modified RIFLE criteria in critically ill children with acute kidney injury. Kidney Int 2007;71:1028-35.
21. Vachvanichsanong P, Dissaneewate P, Lim A, McNeil E. Childhood Acute Renal Failure: 22-Year Experience in a University Hospital in Southern Thailand. Pediatrics 2006;118:786-91.
22. Flynn JT. Choice of dialysis modality for management of pediatric acute renal failure. Pediatr Nephrol 2002;17:61-9.

There are 22 citations in total.

Details

Primary Language	Turkish
Journal Section	Research Article
Authors	Osman Dönmez This is me Oğuzhan Durmaz This is me
Publication Date	December 1, 2009
Published in Issue	Year 2009 Volume: 7 Issue: 3

Cite

APA	Dönmez, O., & Durmaz, O. (2009). Clinical Outcomes of Acute Renal Failure in Children. Güncel Pediatri, 7(3), 57-61.
AMA	Dönmez O, Durmaz O. Clinical Outcomes of Acute Renal Failure in Children. Güncel Pediatri. December 2009;7(3):57-61.
Chicago	Dönmez, Osman, and Oğuzhan Durmaz. “Clinical Outcomes of Acute Renal Failure in Children”. Güncel Pediatri 7, no. 3 (December 2009): 57-61.
EndNote	Dönmez O, Durmaz O (December 1, 2009) Clinical Outcomes of Acute Renal Failure in Children. Güncel Pediatri 7 3 57–61.
IEEE	O. Dönmez and O. Durmaz, “Clinical Outcomes of Acute Renal Failure in Children”, Güncel Pediatri, vol. 7, no. 3, pp. 57–61, 2009.
ISNAD	Dönmez, Osman - Durmaz, Oğuzhan. “Clinical Outcomes of Acute Renal Failure in Children”. Güncel Pediatri 7/3 (December 2009), 57-61.
JAMA	Dönmez O, Durmaz O. Clinical Outcomes of Acute Renal Failure in Children. Güncel Pediatri. 2009;7:57–61.
MLA	Dönmez, Osman and Oğuzhan Durmaz. “Clinical Outcomes of Acute Renal Failure in Children”. Güncel Pediatri, vol. 7, no. 3, 2009, pp. 57-61.
Vancouver	Dönmez O, Durmaz O. Clinical Outcomes of Acute Renal Failure in Children. Güncel Pediatri. 2009;7(3):57-61.