Çocuklarda Kolflisin Zehirlenmesi: 7 Olgu Sunumu

Year 2009, Volume: 7 Issue: 3, 96 - 100, 01.12.2009

Mehmet Karacan Haşim Olgun Zuhal Keskin Yıldırım Cahit Karakelleoğlu Naci Ceviz

Abstract

Kolflisin, çeflitli hastalıkların tedavisinde primer olarak kullanılan bir ilaçtır.Kolflisin zehirlenmesi, sık görülmemekle birlikte, çoğul organ tutulumuna nedenolarak hayatı tehdit edici karakterde seyredebilir. Kolflisin zehirlenmesi olanyedi çocuk hasta sunuyoruz. Hastaların yaflları 1 ila 9 arasında idi. Altı hastanınaldıkları kolflisin miktarları 0,16 mg/kg ile 0,39 mg/kg arasındaydı, en sık görülenbulgu kusma ve ishal idi. Bir hastanın almıfl olduğu miktar ise bilinmiyordu. Birhasta kaybedildi, diğer hastalar ise sekelsiz düzeldi. Kolflisin zehirlenmesininciddiyeti, alınan doza ve hastaneye baflvuru zamanına bağlı görünmektedir.Kolflisin zehirlenmesi sonrasında mümkün olan en kısa sürede semptomatiktedavi yapılmalıdır

Keywords

Kolflisin, çocuklar, zehirlenme

Colchicine Poisoning in Children: 7 Case Reports

Abstract

Colchicine is a drug that has been used primarily in several diseases.Colchicine poisoning is an infrequent but potentially life-threatening problemcharacterized by multiorgan involvement. We present seven children withcolchicine poisoning. Their ages ranged between 1 and 9 years. In six children,the amount of colchicine consumed was between 0.16 and 0.39 mg/kg; themost frequent findings were diarrhea and vomiting. In one patient, the ingestedamount was unknown. One of the patients died and all others recovered withoutsequelae. The severity of colchicine poisoning tends to be related to thedosage of ingested drug and the time of admission to hospital. Symptomatictreatment should be started as soon as possible in colchicine poisoning

Keywords

Colchicine, children, poisoning

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