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Year 2006, Volume: 4 Issue: 2, 21 - 25, 01.06.2006

Abstract

References

  • 1. Türk Neonatoloji Derne¤i Neonatoloji . Sarılıklar. Ed: Murat Yurdakök, Gülşen Erdem. Ankara 2004: 559-78.
  • 2. Wong RJ, Desandre GH, Sibley E, Stevenson DK. Neonatal Jaundice and liver diseases. In: Martin RJ, Fanaroff AA, Walsh MC (eds). Neonatal-Perinatal Medicine. Diseases of the Fetus and Infant, 8th edition Mosby Elsevier 2006; 1419-65.
  • 3. Steffensrud S,. Hyperbilirubinemia in term and near-term infants: Kernicterus on the rise. Newborn and Infant Nursing Reviews 2004: 4:191-200.
  • 4. Hansen TW. Bilirubin oxiadation in brain. Molecular Genetics and Metabolism. 2000: 71,411-7.
  • 5. Schwoebel A, Bhutani VK, Johnston L. Kernicterus: A '' Neverevent'' in healthy term and near-term newborns. Newborn and Infant Nursing Reviews 2004: 4;201-10.
  • 6. Maisels MJ. Physiologic jaundice. In: Macdonald MG, Mullet MD, Seshia MMK (eds) Avery's Neonatology Pathophysiology & Management of the Newborn. 6th Edition. Philedelphia Lippincott Saunders 2005: 768-846.
  • 7. Dennery PA, Seidman DS, Stevenson DK. Neonatal hyperbilirubinemia. N Engl J Med 2002: 344;581-90.
  • 8. American Academy of Pediatrics: Provisional Committee for quality improvement and subcommittee on hyperbilirubinemia. Practice parameter: Management of Hyperbilirubinemia in the healthy newborn. Pediatrics 1994: 94;558-62.
  • 9. Gourley GR. Breast-feeding, neonatal jaundice and kernicterus. Semin Neonatol. 2002: 7;137-141.
  • 10. Gartner LW. Breastfeeding and jaundice.Perinatol 2001: 21;25-9.
  • 11. Huang MJ, Kua KE, Teng HC, Tang KS, Weng HW, Huang CS. Risk factors for severe hyperbilirubinemia in neonates. Pediatr Res 2004: 56:682-29.
  • 12. American Academy of Pediatrics: Clinical Practice Guideline: Subcommittee on Hyperbilirubinemia. Management of Hyperbilirubinemia in the Newborn infant 35 or more week of gestation. Pediatrics 2004: 114;297-316.
  • 13. Amin SB. Clinical assessment of bilirubin-induced neurotoxicity in premature infants. Semin Perinatol 2004: 5;340-7.
  • 14. Bhutani VK, Johnson LH, Keren R. Diagnosis and management of hyperbilirubinemia in the term neonate: for a safer first week. Pediatr Clin North Am 2004: 4;843-61.
  • 15. Dai J, Parry DM, Krahn J. Transcutaneous bilirubinometry: Its role in the assesment of neonatal jaundice. Clinical Biochemistry 1997: 30;1-9.
  • 16. Yasuda S, Itoh S, Isobe K et al. New transcutaneous jaundice device with two optical paths. J Perinat Med 2003: 31;81-8.
  • 17. Newman TB, Xiong B, Gonzales WM, Escobar GJ. Prediction and prevention of extreme neonatal hyperbilirubinemia in a mature health maintenance organisation. Arch Pediatr Adolesc Med 2000; 154:1140-7.
  • 18. Bhutani VK, Johnson L, Sivieri EM. Predictive ability of a predischarge hour-spesific serum bilirubin for subsequent significant hyperbilirubinemia in healthy term and near-term newborns. Pediatrics 1999: 103;6-14.
  • 19. Stevenson DK, Fanaroff AA, Maisels JM et al. Prediction of hyperbilirubinemia in near-term and term infants. Pediatrics 2001: 108;31-9.
  • 20. Leslie GI, Philips JB, Cassady G. Capillary and venous bilirubin values: are they really different? Am J Dis Child 1987: 141:1199-200.
  • 21. Kaplan M, Hammerman C. Glucose -6 phosphate dehydrogenase deficiency: A potential source of severe neonatal hyperbilirubinemia and kernicterus. Semin Neonatol 2002: 7;121-8.
  • 22. Atay E, Bozaykut A, Ipek IO. Glucose- 6 phosphate dehydrogenase deficiency in neonatal indirect hyperbilirubinemia. J Trop Pediatr 2006; 52: 56-8.
  • 23. Büyükokuyan ME, Süleyman H. Glukoz 6 fosfat dehidrogenaz eksikli¤i. Türkiye Klinikleri T›p Bilimleri Dergisi 2001; 21:415-9.
  • 23. Herschel M, Karrison T, Wen M, Calderelli L, Baron B. Evaluation of the direct antiglobulin (Coombs') test for identifying newborns at risk for hemolysis as determined by end-tidal carbon monoxide concentration (ETCOc); and comparison of the Coombs' test with ETCOc for detecting significant jaundice. J Perinatol 2002: 22:341-7.

İndirekt Hiperbilirubinemi/Nedenler ve Tanı

Year 2006, Volume: 4 Issue: 2, 21 - 25, 01.06.2006

Abstract

Zamanında doğan bebeklerin % 20-50'si, prematürelerin % 60-80'i yaşamın ilk günlerinde hiperbilirubinemi sorunu ile karşı karşıya kalırlar. Erişkinlerden farklı olarak bilirubin düzeyi 5 mg/dl üzerine çıkmadan yenidoğanlarda ikter belirginleşmez 1,2,3 . Yenidoğan bebek doğumla birlikte intrauterin dönemden ekstrauterin döneme hızlı bir geçiş göstermekte, hem katabolizması ve bilirubin fizyolojisinde önemli değişiklikler olmaktadır. Fizyolojik hiperbilirubineminin nedenleri arasında, yenidoğan eritrosit sayısının çocukluk dönemine göre fazla olduğu, eritrosit yaşam sürelerinin 45-90 gün gibi kı- sa oluşu, özellikle prematürelerde bu sürenin 35-50 gün gibi daha da kısa oluşu başta gelen nedenler arasındadır. Bu nedenle bir yenidoğan bebek erken dönemde erişkin bir insanın yaklaşık 3 katı fazla bilirubin yüküyle karşılaşır 2,3 .

References

  • 1. Türk Neonatoloji Derne¤i Neonatoloji . Sarılıklar. Ed: Murat Yurdakök, Gülşen Erdem. Ankara 2004: 559-78.
  • 2. Wong RJ, Desandre GH, Sibley E, Stevenson DK. Neonatal Jaundice and liver diseases. In: Martin RJ, Fanaroff AA, Walsh MC (eds). Neonatal-Perinatal Medicine. Diseases of the Fetus and Infant, 8th edition Mosby Elsevier 2006; 1419-65.
  • 3. Steffensrud S,. Hyperbilirubinemia in term and near-term infants: Kernicterus on the rise. Newborn and Infant Nursing Reviews 2004: 4:191-200.
  • 4. Hansen TW. Bilirubin oxiadation in brain. Molecular Genetics and Metabolism. 2000: 71,411-7.
  • 5. Schwoebel A, Bhutani VK, Johnston L. Kernicterus: A '' Neverevent'' in healthy term and near-term newborns. Newborn and Infant Nursing Reviews 2004: 4;201-10.
  • 6. Maisels MJ. Physiologic jaundice. In: Macdonald MG, Mullet MD, Seshia MMK (eds) Avery's Neonatology Pathophysiology & Management of the Newborn. 6th Edition. Philedelphia Lippincott Saunders 2005: 768-846.
  • 7. Dennery PA, Seidman DS, Stevenson DK. Neonatal hyperbilirubinemia. N Engl J Med 2002: 344;581-90.
  • 8. American Academy of Pediatrics: Provisional Committee for quality improvement and subcommittee on hyperbilirubinemia. Practice parameter: Management of Hyperbilirubinemia in the healthy newborn. Pediatrics 1994: 94;558-62.
  • 9. Gourley GR. Breast-feeding, neonatal jaundice and kernicterus. Semin Neonatol. 2002: 7;137-141.
  • 10. Gartner LW. Breastfeeding and jaundice.Perinatol 2001: 21;25-9.
  • 11. Huang MJ, Kua KE, Teng HC, Tang KS, Weng HW, Huang CS. Risk factors for severe hyperbilirubinemia in neonates. Pediatr Res 2004: 56:682-29.
  • 12. American Academy of Pediatrics: Clinical Practice Guideline: Subcommittee on Hyperbilirubinemia. Management of Hyperbilirubinemia in the Newborn infant 35 or more week of gestation. Pediatrics 2004: 114;297-316.
  • 13. Amin SB. Clinical assessment of bilirubin-induced neurotoxicity in premature infants. Semin Perinatol 2004: 5;340-7.
  • 14. Bhutani VK, Johnson LH, Keren R. Diagnosis and management of hyperbilirubinemia in the term neonate: for a safer first week. Pediatr Clin North Am 2004: 4;843-61.
  • 15. Dai J, Parry DM, Krahn J. Transcutaneous bilirubinometry: Its role in the assesment of neonatal jaundice. Clinical Biochemistry 1997: 30;1-9.
  • 16. Yasuda S, Itoh S, Isobe K et al. New transcutaneous jaundice device with two optical paths. J Perinat Med 2003: 31;81-8.
  • 17. Newman TB, Xiong B, Gonzales WM, Escobar GJ. Prediction and prevention of extreme neonatal hyperbilirubinemia in a mature health maintenance organisation. Arch Pediatr Adolesc Med 2000; 154:1140-7.
  • 18. Bhutani VK, Johnson L, Sivieri EM. Predictive ability of a predischarge hour-spesific serum bilirubin for subsequent significant hyperbilirubinemia in healthy term and near-term newborns. Pediatrics 1999: 103;6-14.
  • 19. Stevenson DK, Fanaroff AA, Maisels JM et al. Prediction of hyperbilirubinemia in near-term and term infants. Pediatrics 2001: 108;31-9.
  • 20. Leslie GI, Philips JB, Cassady G. Capillary and venous bilirubin values: are they really different? Am J Dis Child 1987: 141:1199-200.
  • 21. Kaplan M, Hammerman C. Glucose -6 phosphate dehydrogenase deficiency: A potential source of severe neonatal hyperbilirubinemia and kernicterus. Semin Neonatol 2002: 7;121-8.
  • 22. Atay E, Bozaykut A, Ipek IO. Glucose- 6 phosphate dehydrogenase deficiency in neonatal indirect hyperbilirubinemia. J Trop Pediatr 2006; 52: 56-8.
  • 23. Büyükokuyan ME, Süleyman H. Glukoz 6 fosfat dehidrogenaz eksikli¤i. Türkiye Klinikleri T›p Bilimleri Dergisi 2001; 21:415-9.
  • 23. Herschel M, Karrison T, Wen M, Calderelli L, Baron B. Evaluation of the direct antiglobulin (Coombs') test for identifying newborns at risk for hemolysis as determined by end-tidal carbon monoxide concentration (ETCOc); and comparison of the Coombs' test with ETCOc for detecting significant jaundice. J Perinatol 2002: 22:341-7.
There are 24 citations in total.

Details

Primary Language Turkish
Journal Section Research Article
Authors

Nilgün Kültürsay This is me

Şebnem Çalkavur This is me

Publication Date June 1, 2006
Published in Issue Year 2006 Volume: 4 Issue: 2

Cite

APA Kültürsay, N., & Çalkavur, Ş. (2006). İndirekt Hiperbilirubinemi/Nedenler ve Tanı. Güncel Pediatri, 4(2), 21-25.
AMA Kültürsay N, Çalkavur Ş. İndirekt Hiperbilirubinemi/Nedenler ve Tanı. Güncel Pediatri. June 2006;4(2):21-25.
Chicago Kültürsay, Nilgün, and Şebnem Çalkavur. “İndirekt Hiperbilirubinemi/Nedenler Ve Tanı”. Güncel Pediatri 4, no. 2 (June 2006): 21-25.
EndNote Kültürsay N, Çalkavur Ş (June 1, 2006) İndirekt Hiperbilirubinemi/Nedenler ve Tanı. Güncel Pediatri 4 2 21–25.
IEEE N. Kültürsay and Ş. Çalkavur, “İndirekt Hiperbilirubinemi/Nedenler ve Tanı”, Güncel Pediatri, vol. 4, no. 2, pp. 21–25, 2006.
ISNAD Kültürsay, Nilgün - Çalkavur, Şebnem. “İndirekt Hiperbilirubinemi/Nedenler Ve Tanı”. Güncel Pediatri 4/2 (June 2006), 21-25.
JAMA Kültürsay N, Çalkavur Ş. İndirekt Hiperbilirubinemi/Nedenler ve Tanı. Güncel Pediatri. 2006;4:21–25.
MLA Kültürsay, Nilgün and Şebnem Çalkavur. “İndirekt Hiperbilirubinemi/Nedenler Ve Tanı”. Güncel Pediatri, vol. 4, no. 2, 2006, pp. 21-25.
Vancouver Kültürsay N, Çalkavur Ş. İndirekt Hiperbilirubinemi/Nedenler ve Tanı. Güncel Pediatri. 2006;4(2):21-5.