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Treatment of Pediatric Bipolar Disorder

Year 2014, Volume: 6 Issue: 2, 92 - 106, 06.11.2014
https://doi.org/10.5455/cap.20130707024051

Abstract

Although once pediatric bipolar disorder had been perceived as a very rarely seen psychiatric disorder, studies conducted within the last two decades revealed that this disorder is more often than assumed. Childhood and adolescent onset bipolar disorder causes and leads serious familial and academic disturbances, more frequent subtance use, precarios sexual intercourses, adolescent pregnancy and tendency to delinquency. Lifelong functionality is worse than adult onset. It could be more difficult to be diagnosed and could take longer time period for the diagnosis than adult onset. Difficulties of compliance to treatment can be seen more frequently because of the behavioural age characteristics of this group. Diagnostic controversies about the pediatric bipolar disorder also led disagreement about the treatment. In this review treatment approaches in the child and adolescent onset bipolar disorder have been discussed.

References

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Pediatrik Bipolar Bozukluk Tedavisi

Year 2014, Volume: 6 Issue: 2, 92 - 106, 06.11.2014
https://doi.org/10.5455/cap.20130707024051

Abstract

Önceleri pediatrik bipolar bozukluk çok nadir görülen bir psikiyatrik bozukluk olarak düşünülse de, son 20 yıldaki araştırmalar bozukluğun sanılandan çok daha yaygın olduğunu ortaya koymuştur. Çocuk ve ergenlik başlangıçlı bipolar bozukluk ciddi ailesel ve akademik sorunlara, daha sık madde kullanımına, riskli cinsel ilişkilere, ergen gebeliği ve suça yatkınlığa neden olmaktadır. Erişkin başlangıçlıya göre yaşam boyu daha kötü bir işlevsellik söz konusudur. Tanı konulması daha güç olabilmekte ve tanı konulana kadar geçen süre erişkin bipolar bozukluğuna göre daha uzun olabilmektedir. Bu yaş grubunun özelliklerinden dolayı tedavi uyumu ile ilişkili problemlere daha sık rastlanmaktadır. Pediatrik bipolar bozukluktaki bu tanı ile ilgili karmaşa, tedavi konusunda da anlaşmazlıklara yol açmıştır. Bu gözden geçirmede çocuk ve ergenlik başlangıçlı bipolar bozukluktaki tedavi yaklaşımları ele alınmıştır.

References

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  • Orhan A, Abalı O. Çocukluktan ergenliğe iki uçlu bozukluk: tanı zorlukları ve ekhastalıklar üzerine bir gözden geçirme. Journal of Mood Disorders 2011; 1:126-135.
  • Tohen M, Kryzhanovskaya L, Carlson G, Delbello M, Wozniak J, Kowatch R et al . Olanzapine versus placebo in the treatment of adolescents with bipolar mania. Am J Psychiatry 2007; 164:1547-1556.
  • Haas M, Delbello MP, Pandina G, Kushner S, Van Hove I, Augustyns I et al. Risperidone for the treatment of acute mania in in children and adolescents with bipolar disorder: a randomized, double-blind, placebo-controlled study. Bipolar Disord 2009; 11:687-700.
  • Pathak S, Findling RL, Earley WR, Acevedo LD, Stankowski J, Delbello MP. Efficacy and safety of quetiapine in children and adolescents with mania associated with bipolar I disorder: a 3-week, double-blind, placebo-controlled trial. J Clin Psychiatry 2013; 74:e100-109.
  • Findling RL, McNamara NK, Youngstrom EA, Stansbrey RJ, Frazier TW, Lingler J et al. An open-label study of aripiprazole in children with a bipolar disorder. J Child Adolesc Psychopharmacol. 2011; 21:345-351.
  • Wagner KD, Kowatch RA, Emslie GJ, Findling RL, Wilens TE, McCague K et al. A double-blind, randomized, placebocontrolled trial of oxcarbazepine in the treatment of bipolar disorder in children and adolescents. Am J Psychiatry 2006; 163:1179–1186.
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  • DelBello MP, Findling RL, Kushner S, Wang D, Olson WH, Capece JA et al. A pilot controlled trial of topiramate for mania in children and adolescents with bipolar disorder. J Am Acad Child Adolesc Psychiatry 2005; 44:539-547.
  • Wagner KD, Kowatch RA, Emslie GJ, Findling RL, Wilens TE, McCague K et al. A double-blind, randomized, placebocontrolled trial of oxcarbazepine in the treatment of bipolar disorder in children and adolescents. Am J Psychiatry 2006; 163:1179-1186.
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  • Pavuluri MN, Henry DB, Carbray JA, Sampson G, Naylor MW, Janicak PG. Open-label prospective trial of risperidone in combination with lithium or divalproex sodium in pediatric mania. J Affect Disord 2004; 82(suppl 1):S103-S111.
  • Findling RL, McNamara NK, Gracious BL, Youngstrom EA, Stansbrey RJ, Reed MD et al. Combination lithium and divalproex sodium in pediatric bipolarity. J Am Acad Child Adolesc Psychiatry 2003; 42:895-901.
  • Findling RL, McNamara NK, Stansbrey R, Gracious BL, Whipkey RE, Demeter CA et al. Combination lithium and divalproex sodium in pediatric bipolar symptom restabilization. J Am Acad Child Adolesc Psychiatry 2006; 45:142-148.
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Details

Primary Language Turkish
Journal Section Review
Authors

Ayten Erdoğan This is me

Sema Kurban This is me

Özhan Yalçın This is me

Publication Date November 6, 2014
Published in Issue Year 2014 Volume: 6 Issue: 2

Cite

AMA Erdoğan A, Kurban S, Yalçın Ö. Pediatrik Bipolar Bozukluk Tedavisi. Psikiyatride Güncel Yaklaşımlar - Current Approaches in Psychiatry. June 2014;6(2):92-106. doi:10.5455/cap.20130707024051

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