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Psychiatric Disorders in Children and Adolescents with Epilepsy

Year 2013, Volume: 5 Issue: 1, 60 - 77, 01.03.2013
https://doi.org/10.5455/cap.20130505

Abstract

Epilepsy is a chronic disease with a high morbidity. Many recent studies have shown that psychiatric disorders are commonly encountered in children and adolescents with epilepsy. Depression, anxiety disorders and attention deficit hyperactivity disorder are among the most common psychiatric disorders. Many factors, including demographic variables, epilepsy related factors and psychosocial factors, have been suggested to have a role on the development of psychiatric disorders in epilepsy. In the management of psychiatric comorbidities, cooperation between disciplines, education of the patient and family and psychosocial support are of vital importance. Recent studies have shown that some psychotropic agents can be used with a generally high safety and efficacy in children and adolescents with epilepsy.

References

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  • Kanner AM. Psychiatric comorbidity in patients with developmental disorders and epilepsy: a practical approach to its diagnosis and treatment. Epilepsy Behav 2002; 3(6S1):7-13.
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  • Trevathan E. Seizures and epilepsy among children with language regression and autistic spectrum disorders. J Child Neurol 2004; 19(suppl 1):S49-S57.
  • Kanner AM. Psychosis of epilepsy: a neurologists perspective. Epilepsy Behav 2000; 1:219-227.
  • Hesdorffer DC, Ishihara L, Mynepalli L, Webb DJ, Weil J, Hauser WA. Epilepsy, suicidality, and psychiatric disorders: a bidirectional association. Ann Neurol 2012; 72:184-191.
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Epilepsi Tanılı Çocuk ve Ergenlerde Ruhsal Bozukluklar

Year 2013, Volume: 5 Issue: 1, 60 - 77, 01.03.2013
https://doi.org/10.5455/cap.20130505

Abstract

Epilepsi yüksek morbiditeye sahip kronik bir hastalıktır. Son yıllarda yapılmış çok sayıda araştırma epilepsi tanılı çocuk ve ergenlerde ruhsal bozuklukların sık olarak görüldüğünü göstermiştir. En sık görülen ruhsal bozukluklar arasında depresyon, anksiyete bozuklukları ve dikkat eksikliği hiperaktivite bozukluğu yer almaktadır. Aralarında demografik değişkenler, epilepsi ile ilişkili nedenler ve psikososyal faktörler olmak üzere çok sayıda faktörün epilepside ruhsal bozuklukların gelişiminde rol oynadığı düşünülmektedir. Ruhsal bozukluk eş tanılarına yaklaşımda disiplinler arası işbirliği, hasta ve ailenin eğitimi ve psikososyal destek büyük önem taşımaktadır. Araştırmalar bazı psikotrop ilaçların epilepsi tanılı çocuk ve ergenlerde genel olarak yüksek bir güvenilirlik ve etkinlikle kullanılabileceğini göstermiştir.

References

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  • Camfield CS, Camfield PR, Gordon K, Wirrell E, Dooley JM. Incidence of epilepsy in childhood and adolescence. a population-based study in Nova Scotia from 1977 to 19 Epilepsia 1996; 37:19-23.
  • Ott D, Caplan R, Guthrie D, Siddarth P, Komo S, Shields WD et al. Measures of psychopathology in children with complex partial seizures and primary generalized epilepsy with absence. J Am Acad Child Adolesc Psychiatry 2001; 40:907-914.
  • Ott D, Siddarth P, Gurbani S, Koh S, Tournay A, Shields WD et al. Behavioral disorders in pediatric epilepsy: unmet psychiatric need. Epilepsia 2003; 44:591-597.
  • Plioplys S. Depression in children and adolescents with epilepsy. Epilepsy Behav 2003; 4(Suppl 3):S39-S45.
  • Kanner AM. Psychiatric comorbidity in patients with developmental disorders and epilepsy: a practical approach to its diagnosis and treatment. Epilepsy Behav 2002; 3(6S1):7-13.
  • Pellock JM. Defining the problem: psychiatric and behavioral comorbidity in children and adolescents with epilepsy. Epilepsy Behav 2004; 5(suppl 3):S3-S9.
  • Jones JE, Austin JK, Caplan R, Dunn D, Plioplys S, Salpekar JA. Psychiatric disorders in children and adolescents who have epilepsy. Pediatr Rev 2008; 29:9-14.
  • Trevathan E. Seizures and epilepsy among children with language regression and autistic spectrum disorders. J Child Neurol 2004; 19(suppl 1):S49-S57.
  • Kanner AM. Psychosis of epilepsy: a neurologists perspective. Epilepsy Behav 2000; 1:219-227.
  • Hesdorffer DC, Ishihara L, Mynepalli L, Webb DJ, Weil J, Hauser WA. Epilepsy, suicidality, and psychiatric disorders: a bidirectional association. Ann Neurol 2012; 72:184-191.
  • Austin JK, Harezlak J, Dunn DW, Huster GA, Rose DF, Ambrosius WT. Behavior problems in children before first recognized seizures. Pediatrics 2001; 107:115-122
  • Elger CE, Hoppe C. What is depression in epilepsy? Front Neurol 2011; 2:79.
  • Ekinci O, Titus JB, Rodopman AA, Berkem M, Trevathan E. Depression and anxiety in children and adolescents with epilepsy: prevalence, risk factors, and treatment. Epilepsy Behav 2009; 14:8-18.
  • Devinsky O. Psychiatric comorbidity in patients with epilepsy: implications for diagnosis and treatment. Epilepsy Behav 2003; 4(suppl 4):2-10.
  • Tosun A, Gokcen S, Ozbaran B, Serdaroglu G, Polat M, Tekgul H et al. The effect of depression on academic achievement in children with epilepsy. Epilepsy Behav 2008; 13:494-498.
  • Caplan R, Siddarth P, Gurbani S, Hanson R, Sankar R, Shields WD. Depression and anxiety disorders in pediatric epilepsy. Epilepsia 2005; 46:720-730.
  • Barry JJ, Ettinger AB, Friel P, Gilliam FG, Harden CL, Hermann B et al. Consensus statement: the evaluation and treatment of people with epilepsy and affective disorders. Epilepsy Behav 2008; 13(suppl 1):1-29.
  • Oguz A, Kurul S, Dirik E. Relationship of epilepsy-related factors to anxiety and depression scores in epileptic children. J Child Neurol 2002; 17:37-40.
  • Thome-Souza S, Kuczynski E, Assumpção Jr F, Rzezak P, Fuentes D, Fiore L et al. Which factors may play a pivotal role on determining the type of psychiatric disorder in children and adolescents with epilepsy? Epilepsy Behav 2004; 5:988-994.
  • Devinsky O, Westbrook L, Cramer J, Glassman M, Perrine K, Camfield C. Risk factors for poor health-related quality of life in adolescents with epilepsy. Epilepsia 1999; 40:1715-1720.
  • Stores G. School-children with epilepsy at risk for learning and behaviour problems. Dev Med Child Neurol 1978; 20:502-508.
  • Datta SS, Premkumar TS, Chandy S, Kumar S, Kirubakaran C, Gnanamuthu C et al. Behaviour problems in children and adolescents with seizure disorder: associations and risk factors. Seizure 2005; 14:190-197.
  • Paradiso S, Hermann BP, Blumer D, Davies K, Robinson RG. Impact of depressed mood on neuropsychological status in temporal lobe epilepsy. J Neurol Neurosurg Psychiatry 2001; 70:180-185.
  • Sanchez-Gistau V, Sugranyes G, Baillés E, Carreño M, Donaire A, Bargalló N et al. Is major depressive disorder specifically associated with mesial temporal sclerosis? Epilepsia 2012; 53:386-392.
  • Titus JB, Kanive R, Sanders SJ, Blackburn LB. Behavioral profiles of children with epilepsy: parent and teacher reports of emotional, behavioral, and educational concerns on the BASC-2. Psychol Schools 2008; 45:892-903.
  • De Araşjo Filho GM, Pascalicchio TF, Sousa Pda S, Lin K, Ferreira Guilhoto LM, Yacubian EM. Psychiatric disorders in juvenile myoclonic epilepsy: a controlled study of 100 patients. Epilepsy Behav 2007; 10:437-441.
  • Perini GI, Tosin C, Carraro C, Bernasconi G, Canevini MP, Canger R et al. Interictal mood and personality disorders in temporal lobe epilepsy and juvenile myoclonic epilepsy. J Neurol Neurosurg Psychiatry 1996; 61:601-605.
  • Austin JK, Dunn DW, Caffrey HM, Perkins SM, Harezlak J, Rose DF. Recurrent seizures and behavior problems in children with first recognized seizures: a prospective study. Epilepsia 2002; 43:1564-1573.
  • Turky A, Beavis JM, Thapar AK, Kerr MP. Psychopathology in children and adolescents with epilepsy: an investigation of predictive variables. Epilepsy Behav 2008; 12:136-144.
  • Rodenburg R, Meijer AM, Dekovic´ M, Aldenkamp AP. Family factors and psychopathology in children with epilepsy: a literature review. Epilepsy Behav 2005; 6:488-503.
  • Rodenburg R, Marie Meijer A, Dekovic´ M, Aldenkamp AP. Family predictors of psychopathology in children with epilepsy. Epilepsia 2006; 47:601-614.
  • Carlton-Ford S, Miller R, Nealeigh N, Sanchez N. The effects of perceived stigma and psychological over-control on the behavioural problems of children with epilepsy. Seizure 1997; 6:383-391.
  • Fazlıoğlu K, Hocaoğlu Ç, Sönmez FM, Cansu A. Epilepsi tanısı konan çocukların aile işlevleri, anne- babalarındaki kaygı ve başa çıkma tutumları. Yeni Symposium 2010; 48:198-206.
  • Hodes M, Garralda ME, Rose G, Schwartz R. Maternal expressed emotion and adjustment in children with epilepsy. J Child Psychol Psychiatry 1999; 40:108310
  • Baker GA. Assessment of quality of life in people with epilepsy: some practical implications. Epilepsia 2001; 42(suppl 3):66-69.
  • Baker GA, Brooks J, Buck D, Jacoby A. The stigma of epilepsy: a European perspective. Epilepsia 2000; 41:98-104
  • MacLeod JS, Austin JK. Stigma in the lives of adolescents with epilepsy: a review of the literature. Epilepsy Behav 2003; 4:112-117.
  • Mazarati A, Shin D, Auvin S, Caplan R, Sankar R. Kindling epileptogenesis in immature rats leads to persistent depressive behavior. Epilepsy Behav 2007; 10:3773
  • Drevets WC, Frank E, Price JC, Kupfer DJ, Holt D, Greer PJ et al. PET imaging of serotonin 1A receptor binding in depression. Biol Psychiatry 1999; 46:1375-1387.
  • Gilliam FG, Maton BM, Martin RC, Sawrie SM, Faught RE, Hugg JW et al. Hippocampal 1H-MRSI correlates with severity of depression symptoms in temporal lobe epilepsy. Neurology 2007; 68:364-368.
  • Brent DA, Crumrine PK, Varma R, Brown RV, Allan MJ. Phenobarbital treatment and major depressive disorder in children with epilepsy: a naturalistic follow-up. Pediatrics 1990; 85:1086-1091.
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Details

Primary Language Turkish
Journal Section Review
Authors

Özalp Ekinci This is me

Fevziye Toros This is me

Publication Date March 1, 2013
Published in Issue Year 2013 Volume: 5 Issue: 1

Cite

AMA Ekinci Ö, Toros F. Epilepsi Tanılı Çocuk ve Ergenlerde Ruhsal Bozukluklar. Psikiyatride Güncel Yaklaşımlar - Current Approaches in Psychiatry. March 2013;5(1):60-77. doi:10.5455/cap.20130505

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