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Elektrokonvulzif Tedavi: Bir Güncelleme

Year 2012, Volume: 4 Issue: 3, 350 - 370, 01.09.2012
https://doi.org/10.5455/cap.20120421

Abstract

Psikiyatrik hastalıkların tedavisinde kullanılmaya başlandığından beri elektrokonvulzif tedavinin etki ve yan etkileri tartışılmaktadır. Antidepresan etki mekanizmaları birçok araştırmaya konu olmuş, önemli bulgular elde edilmiştir. Ancak yöntemsel farklılıklar ve uygulama protokolündeki değişiklikler araştırmaların ilerlemesinin önünde en büyük engel olmuşlardır. Birçok araştırmada antikonvülzan etki ve nöbet eşiğindeki yükselme ölçü olarak alınmış olmasına karşın bu durum kesinleştirilememiştir. Hastalıklarla ilgili değişkenlerin araştırma bulgularını etkilemiş olma olasılığı bulunmaktadır. Bu yazıda elektokonvulzif tedavinin uygulama biçimleri ve etki mekanizmalarıyla ilgili güncel literatür incelenmiştir.

References

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  • Murat İlhan Atagün, Dr., Bakırköy Ruh ve Sinir Hastalıkları Hastanesi, İstanbul; Murat Serkan Yıldırım,
  • Dr., Bakırköy Ruh ve Sinir Hastalıkları Hastanesi, İstanbul; Özge Canbek, Dr., Bakırköy Ruh ve Sinir Hastalıkları Hastanesi, İstanbul

Electroconvulsive Therapy: An Update

Year 2012, Volume: 4 Issue: 3, 350 - 370, 01.09.2012
https://doi.org/10.5455/cap.20120421

Abstract

Effects and side effects of electroconvulsive therapy have been a subject of debate since the begininng of its use to treat psychiatric disorders. As its antidepressant mechanism of action have been topic of many researches, many valuable findings were obtained ever since. However, methodological differences and different application protocols limited the accumulation of scientific data. Anticonvulsant effect and elevation of seizure threshold have been taken as outcome measures in many researches although it is still controversial. Some variables of treated disorders also may have affected researches. The aim of this article was to investigate current literature regarding application protocols and mechanism of action of electroconvulsive therapy.

References

  • Scott AF. Electroconvulsive therapy, practice and evidence. Br J Psychiatry 2010; 196:171-172.
  • Akdeniz F, Noyan MA. Elektrokonvülsif tedavinin diğer endikasyonları. Ege Psikiyat- ri Dergisi 1998; 3:279-284.
  • Cimilli C. EKT’nin alışılmışın dışında kullanım alanları. Turk Psikiyatr Derg, 1994; 5:279-282.
  • American Psychiatric Association (APA) Task Force on ECT. The practice of ECT: recommendations for treatment, training and privileging. Washington DC, American Psychiatric Association Press,1990.
  • Rabheru K. The use of electroconvulsive therapy in special patient populations. Can J Psychiatry 2001; 46:710-719.
  • Kısa C, Aydemir Ç. Elektrokonvulsif tedavinin etki mekanizması. Psikiyatri Psikoloji Psikofarmakoloji (3P) Dergisi 2003; 11(Ek 4):7-11.
  • Payne NA, Prudic J. Electroconvulsive therapy: Part I a perspective on the evolution and current practice of ECT. J Psychiatr Pract 2009; 15:346-368.
  • Kellner CH, Pritchett JT, Beale MD, Coffey, CE. Handbook of ECT. Washington DC, American Psychiatric Press, 1997.
  • Abrams R. Electroconvulsive therapy, 4th edition. New York, Oxford University Press, 2002.
  • Nobler MS, Sackeim HA. Neurobiological correlates of cognitive side effects of electroconvulsive therapy. J ECT 2008; 24:40-45.
  • Peterchev AV, Rosa MA, Deng ZD, Prudic J, Lisanby SH. Electroconvulsive therapy stimulus parameters: rethinking dosage. J ECT 2010; 26:159-174.
  • Sadock BJ, Sadock VA. Kaplan and Sadock's Synopsis of Psychiatry: Behavioral Sciences/Clinical Psychiatry (Synopsis of Psychiatry), 10th ed. Philadelphia, PA; Lippincott Williams & Wilkins, 2007.
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  • Weinar RD. ECT and seizure threshold: effects of stimulus wave form and electrode placements. Biol Psychiatry 1980; 15:225-241.
  • Petrides G, Braga RJ, Fink M, Knapp MMR, Husain M, Rummans T et al. Seizure threshold in a large sample: ımplications for stimulus dosing strategies in bilateral ECT. J ECT 2009; 25:232-237.
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  • Öztürkoğlu M, Evlice YE, Özpoyraz N, Ünal M, Fettahlıoglu M. Elektrokonvülsif tedavinin antidepresan ekinliği ve yan etkileri. Türk Psikiyatri Derg 1994; 5:109-112.
  • Friedberg J. Shock treatment, brain damage and memory loss: a neurological perspective. Am J Psychiatry 1977; 134:1010-1014.
  • Fink M. Convulsive therapy: a review of first 55 years. J Affect Disord 2001; 63:1-5.
  • American Psychiatric Association. The Practice of ECT: Recommendations for Treatment, Training and Privileging. 2nd ed. Washington, DC, American Psychiatric Press, 2001.
  • Kalinowsky LB, Hippius H. Pharmacological, Convulsive and Other Somatic Treatments in Psychiatry. New York, Grune & Stratton, 1969.
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  • Murat İlhan Atagün, Dr., Bakırköy Ruh ve Sinir Hastalıkları Hastanesi, İstanbul; Murat Serkan Yıldırım,
  • Dr., Bakırköy Ruh ve Sinir Hastalıkları Hastanesi, İstanbul; Özge Canbek, Dr., Bakırköy Ruh ve Sinir Hastalıkları Hastanesi, İstanbul
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Details

Primary Language Turkish
Journal Section Review
Authors

Murat İlhan Atagün This is me

Murat Serkan Yıldırım This is me

Özge Canbek This is me

Publication Date September 1, 2012
Published in Issue Year 2012 Volume: 4 Issue: 3

Cite

AMA Atagün Mİ, Yıldırım MS, Canbek Ö. Elektrokonvulzif Tedavi: Bir Güncelleme. Psikiyatride Güncel Yaklaşımlar - Current Approaches in Psychiatry. September 2012;4(3):350-370. doi:10.5455/cap.20120421

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