Year 2016, Volume 8 , Issue 1, Pages 42 - 51 2016-01-23

Use of Modafinil in Psychiatric Disorders
Psikiyatrik Bozukluklarda Modafinil Kullanımı

Mehmet Kokaçya [1] , Ümit Çöpoğlu [2] , Musa Şahpolat [3] , Mustafa Arı [4]


Modafinil, is a psychostimulant drug with neurochemical and behavourial effects, distinct from those of amphetamine. It is used to treat patients with narcolepsy and other excessive sleepiness. Modafinil has dopaminergic, noradrenergic, histaminergic, glutamergic, serotonergic and GABAergic interac-tions. It is also shown that modafinil has neuroprotective effects via antioxidative mechanisms. Besides modafinil shows initial promise for a variety of off-label indications in psychiatry, including bipolar disorder, attention-deficit/hyperactivity disorder, and schizophrenia. The aim of this article is to review the literature on clinical use of modafinil in psychiatric disorders.
Modafinil narkolepsi ve diğer gündüz uykululuğu yapan hastalıklarda kullanılan amfetaminden farklı nörokimyasal ve davranışsal özellikleri olan psikostimulan bir ilaçtır. Modafinilin dopaminerjik, histaminerjik, noradrenerjik glutamaterjik, GABAerjik ve serotoninerjik etkileşimleri vardır. Ayrıca antioksidatif mekanizmalar aracılığıyla nöroprotektif etkilerinin olduğu da gösterilmiştir. Bunun yanında modafinil; bipolar bozukluk, dikkat eksikliği hiperaktivite bozukluğu ve şizofreni gibi psikiyatrik hastalıklarda endikasyon dışı kullanımıyla ilgili gelecek vaadetmektedir. Bu derlemede modafinilin psikiyatrik hastalıklarda klinik kullanımın ele alınması amaçlanmıştır.
Modafinil, psikiyatrik hastalıklar, ekleme tedavisi
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Primary Language en
Journal Section Review
Authors

Author: Mehmet Kokaçya

Author: Ümit Çöpoğlu

Author: Musa Şahpolat

Author: Mustafa Arı

Dates

Acceptance Date : November 21, 2019
Publication Date : January 23, 2016

Bibtex @ { pgy133534, journal = {Psikiyatride Güncel Yaklaşımlar}, issn = {1309-0658}, eissn = {1309-0674}, address = {}, publisher = {Lut TAMAM}, year = {2016}, volume = {8}, pages = {42 - 51}, doi = {}, title = {Use of Modafinil in Psychiatric Disorders}, key = {cite}, author = {Kokaçya, Mehmet and Çöpoğlu, Ümit and Şahpolat, Musa and Arı, Mustafa} }
APA Kokaçya, M , Çöpoğlu, Ü , Şahpolat, M , Arı, M . (2016). Use of Modafinil in Psychiatric Disorders. Psikiyatride Güncel Yaklaşımlar , 8 (1) , 42-51 . Retrieved from https://dergipark.org.tr/en/pub/pgy/issue/11171/133534
MLA Kokaçya, M , Çöpoğlu, Ü , Şahpolat, M , Arı, M . "Use of Modafinil in Psychiatric Disorders". Psikiyatride Güncel Yaklaşımlar 8 (2016 ): 42-51 <https://dergipark.org.tr/en/pub/pgy/issue/11171/133534>
Chicago Kokaçya, M , Çöpoğlu, Ü , Şahpolat, M , Arı, M . "Use of Modafinil in Psychiatric Disorders". Psikiyatride Güncel Yaklaşımlar 8 (2016 ): 42-51
RIS TY - JOUR T1 - Use of Modafinil in Psychiatric Disorders AU - Mehmet Kokaçya , Ümit Çöpoğlu , Musa Şahpolat , Mustafa Arı Y1 - 2016 PY - 2016 N1 - DO - T2 - Psikiyatride Güncel Yaklaşımlar JF - Journal JO - JOR SP - 42 EP - 51 VL - 8 IS - 1 SN - 1309-0658-1309-0674 M3 - UR - Y2 - 2019 ER -
EndNote %0 Psikiyatride Güncel Yaklaşımlar Use of Modafinil in Psychiatric Disorders %A Mehmet Kokaçya , Ümit Çöpoğlu , Musa Şahpolat , Mustafa Arı %T Use of Modafinil in Psychiatric Disorders %D 2016 %J Psikiyatride Güncel Yaklaşımlar %P 1309-0658-1309-0674 %V 8 %N 1 %R %U
ISNAD Kokaçya, Mehmet , Çöpoğlu, Ümit , Şahpolat, Musa , Arı, Mustafa . "Use of Modafinil in Psychiatric Disorders". Psikiyatride Güncel Yaklaşımlar 8 / 1 (January 2016): 42-51 .
AMA Kokaçya M , Çöpoğlu Ü , Şahpolat M , Arı M . Use of Modafinil in Psychiatric Disorders. pgy. 2016; 8(1): 42-51.
Vancouver Kokaçya M , Çöpoğlu Ü , Şahpolat M , Arı M . Use of Modafinil in Psychiatric Disorders. Psikiyatride Güncel Yaklaşımlar. 2016; 8(1): 51-42.