Parkinson Hastalığında Biliş ve Yaşam Kalitesi

Year 2024, Volume: 16 Issue: 4, 604 - 616, 25.12.2024

Öznur Kalaba , Özlem Merve Cansever Güzeloğlu

https://doi.org/10.18863/pgy.1374234

Cited By: 1

Abstract

Nörodejeneratif bir hastalık olan Parkinson hastalığının yavaş ve ilerleyici olması tanıda gecikmeler yaşanması ile ilişkili olabilmektedir. Genetik, psikiyatrik ve çevresel faktörler gibi farklı değişkenlerin dahil olduğu kompleks bir etiyolojiye sahiptir. Klinik bulgularında bradikinezi, tremor ve rijidite gibi motor semptomlarının yanı sıra depresyon ve bilişsel bozulmalar gibi non-motor semptomlar bildirilmiştir. Bilişsel bozukluklar ve yaşam kalitesinde düşüşlerin de seyredebileceği Parkinson hastalığı hakkında yapılan multidisipliner çalışmalar hastalığın moleküler ve radyolojik bulgularını raporlasa da bilişsel disfonksiyon ve depresyon gibi modaliteler bakımından tutarsız veriler sunulmuştur. Bu çalışmada, Parkinson hastalığının bilişsel ve psikiyatrik bağlamda bildirilen bulguların irdelenerek güncel perspektifin yaşam kalitesi bağlamında sunulması amaçlanmaktadır. İncelemeler doğrultusunda; hastalığın seyrine bağlı olarak görülebilen ve dikkat, bellek, görsel-uzamsal beceriler gibi farklı modalitelerde ortaya çıkan bilişsel bozuklukların hastaların yaşam kalitesini olumsuz yönde etkilediği raporlanmıştır. Depresyon veya depresyon benzeri semptomların ortaya çıkması, Parkinson hastalığı tanısı konan bireylerin genel yaşam kalitesini daha da düşürebilir.

Keywords

Parkinson Hastalığı, Yaşam Kalitesi, Bilişsel Bozukluklar

Cognition and Quality of Life in Parkinson's Disease

Abstract

Parkinson's disease is a neurodegenerative disease known for its progressive prognosis which may be associated with delay in diagnosis. Its etiology can be composed of different modalities involving genetic, psychiatric, and social factors. Findings and observations from clinical settings, motor symptoms such as bradykinesia, tremor, and rigidity have been reported. In addition, non-motor symptoms, such as depression and cognitive dysfunctions have been demonstrated. Moreover, decrease in quality of life has been reported in people with Parkinson’s disease diagnosis. Although multidisciplinary studies on Parkinson's disease indicated general the molecular and radiological findings of the disease, inconsistent data are reported in terms of modalities such as cognitive functioning, depression, and quality of life. The present study aims to present the current perspective in the context of quality of life by examining the findings reported in the cognitive and psychiatric context of Parkinson's disease. According to the findings of this study, cognitive impairments that can be identified based on the course of the disease, manifesting in various forms such as attention, memory, and visual-spatial skills, negatively impact the quality of life for patients. The emergence of depression or depression-like symptoms can further decrease the overall quality of life for individuals diagnosed with Parkinson's disease.

Keywords

Parkinson's Disease, Cognitive Dysfunction, Quality of Life

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