Parotid Adenoid Cystic Carcinoma Metastasizing to the Liver: A Case Report

Abstract

Adenoid cystic carcinoma is a rare malignant neoplasm of the salivary gland. Salivary gland neoplasms constitute 3% of cancers of all sites, of which, 10–15% are malignant. Though adenoid cystic carcinoma is the most common malignant tumor of the submandibular, sublingual and minor salivary glands, it accounts for only 15% of parotid cancers. They are generally slow-growing and spread relentlessly to adjacent structures. Hematogenous spread is more common than lymphatic spread, the common sites of metastasis being the lung, bone, liver, and brain. We present a case of multiple liver metastases occurring 3 years after surgery for adenoid cystic carcinoma of the parotid gland. The primary therapy, metastasis, and outcome of adenoid cystic carcinoma are discussed.

Keywords

• Adenoid cystic carcinoma
• parotid;
• liver

Karaciğere Metastaz Yapan Parotis Adenoid Kistik Karsinomu: Bir Olgu Sunumu

Abstract

Adenoid kistik karsinom tükrük bezinin nadir görülen malign bir tümörüdür. Tükrük bezi neoplazileri tüm kanserlerin %3’ünü oluşturur ve bunların %10-15’i maligndir. Aynı zamanda adenoid kistik karsinom submandibuler, sublingual ve minör tükrük bezlerinin en sık malign tümörüdür. Parotis kanserlerinin sadece %15’ini oluşturur. Bunlar genel olarak yavaş büyür ve çevre dokuya agresif yayılır. Hematojen yayılma, lenfatik yayılmadan daha yaygındır, yaygın metastaz bölgeleri akciğer, kemik, karaciğer ve beyindir. Parotis bezinde adenoid kistik karsinom olan ve ameliyattan 3 yıl sonra multiple karaciğer metastazları görülen vakayı sunduk. Adenoid kistik karsinomun birincil tedavisi, metastazı ve sonucu tartışılmaktadır

Keywords

• Adenoid kistik karsinom;
• parotis;
• karaciğer

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