Screening for G6PD Enzyme Deficiency Among Children aged Five Years and Below in Diyala Province / Iraq.

Year 2019, Volume: 7 Issue: 2, 9 - 14, 31.08.2019

Jalil İbrahim Al-ezzi

Abstract

Background: G6PD deficiency is the most common gene mutation in the world
and the numerous mutations have been classified by the WHO.

Objective: is to estimate the prevalence of G6PD enzyme deficiency among
≤5 years old children attending Al Batool Obstetrics and Pediatric Teaching
Hospital in Baqubah city, Diyala, Iraq, and to see whether screening for G6PD
enzyme deficiency is worthy.

Study setting, design and sample size: A hospital based observational
cross-sectional study consisting of 1500 children (820 boys and 680 girls), in
children aged 5 years and below who attended Al Batool Obstetrics and Pediatric
Teaching Hospital in Baqubah city, Diyala,
Iraq during period from December 1^st 2018 to June30^th 2019.
Blood samples were collected from each child and analyzed for Hemoglobin (Hb)
level, and G6PD enzyme activity assay.

Results: Out of 1500 children tested for enzyme activity only 20
children (1.33%) had low enzyme activity.

Conclusion: The prevalence of G6PD enzyme deficiency is low, so screening
for the enzyme deficiency is not warranted at least in Diyala province.

Keywords

Screening, G6PD, children

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