Geriatrik Popülasyonda Prognostik Nutrisyonel İndex ve Covid19 Mortalite İlişkisi

Abstract

Giriş: COVID-19 enfeksiyonu geçiren yaşlı hastalarda prognostik nutrisyonel indeksin (PNI) prognoz ve mortalite üzerindeki etkisini araştırmayı amaçladık. Gereç ve Yöntemler: Çalışmaya dahil edilen 401 hasta, tümü 65 yaş üstü idi. PNI laboratuvar ve demografik verilerle karşılaştırıldı. Bulgular: Değerlendirme 181'i (%45) kadın ve ortanca yaşı 75.8±7.7 yıl olan 401 hasta üzerinde yapıldı. Üç yüz iki (%75.4) hasta iyileşen gruptaydı. Ortalama PNI değeri iyileşen grupta 41.9±5.9, eksitus grubunda 36.9±7 idi (p<0.001). Çok değişkenli lojistik regresyon analizine göre, COVID-19 hastalarında ileri yaş, yüksek maksimum ferritin düzeyi, yüksek maksimum IL-6 düzeyi ve PNI<40 mortaliteyi öngörmede bağımsız risk faktörleri olarak belirlendi. Sonuç: PNI skorlama sistemini içeren prognostik modellerin COVID-19 progresyonunu değerlendirmede ve hasta takibini geliştirmede faydalı olduğu bulunmuştur. Çalışmamıza dahil edilen hastaların tamamı geriatrik yaş grubunda olduğundan elde ettiğimiz veriler özellikle bu yaş grubundaki hastalarda COVID-19 enfeksiyonunun seyrine kılavuz olabilir.

Keywords

• Beslenme
• Ölüm
• SARS-COV-2
• Yaşlı
• Geriatri

THE RELATIONSHIP OF COVID-19 MORTALITY AND PROGNOSTIC NUTRITIONAL INDEX IN GERIATRIC POPULATION

Abstract

Introduction: We aimed to investigate the effect of Prognostic nutritional index (PNI) on prognosis and mortality among elderly patients with COVID-19 infection. Methods: 401 patients included in the study, all of them were over 65 years old. PNI was compared with laboratory and demographic data. Results: Analysis was made of 401 patients, comprising 181 (45%) females and median age of 75.8±7.7 years. Three hundred and two (75.4%) patients were in the recovered group. Mean PNI value was 41.9±5.9 in the recovered group and 36.9±7 in the exitus group (p<0.001). According to multivariate logistic regression analysis, advanced age, high maximum ferritin level, high maximum IL-6 level and PNI<40 were identified as independent risk factors predicting exitus in COVID-19 patients. Conclusion: Prognostic models which including PNI scoring system, have been found to be useful in assessing the progression of COVID-19 and enhancing patient monitoring. Since all the patients included in our study were in the geriatric age group, the data we obtained may guide the course of COVID-19 infection, especially in patients in this age group.

Keywords

• Nutrition
• Mortality
• SARS-COV-2
• Elderly
• Geriatrics

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