Comparison of Elderly Patients With Younger Age Patients Who Were Diagnosed With Non-Small Cell Lung Cancer in Terms of Operability

Year 2019, Volume: 4 Issue: 2, 114 - 126, 01.08.2019

Hüseyin Fatih Sezer , Aykut Eliçora , Aslı Gül Temel

https://doi.org/10.25279/sak.476377

Abstract

Aim

Elderly patients who
were operated for non-small cell lung cancer were compared with younger age
patients in terms of their demographic characteristics, resection type,
survival, early and late postoperative complications, length of hospital stay,
and effect of older age on operability.

Materials and Methods

A total of 288 patients who underwent
resection for non-small cell lung cancer in Kocaeli University Medical Faculty
Thoracic Surgery Department were examined. Among the patients with adequate
data, 244 patients aged <70 years (Group I, control group) and 44 patients
aged >70 years (advanced age) (Group II, study group) were retrospectively
analyzed.

Results

There were no
statistically significant differences between two groups in terms of
distribution of medical history of patients (p= 0.083), and resection types (p= 0.557). A statistically significant difference
was observed between the two groups in terms of survival (p= 0.013). There was
no statistically significant difference between the two groups in terms of
postoperative early complications (p= 0.514), but there was a statistically
significant difference in terms of postoperative late complications (p= 0.034).
No statistically significant difference was observed between the two groups in
terms of postoperative discharge time (p = 0.916).

Conclusion

This study showed that
the demographic characteristics were significantly similar between the elderly
and younger patients who were treated for non-small cell lung cancer, although
there were partly statistically significant differences in terms of
postoperative morbidity and surgical treatment results. It was also observed
that advanced age alone does not constitute a contraindication for surgical
treatment.

Keywords

Elderly, Lung cancer, surgery

Küçük Hücreli Dışı Akciğer Kanseri Tanılı İleri Yaş Hastaların Opere Edilebilirlik Açısından Erken Yaşlı Hastalarla Karşılaştırılması

Abstract

Amaç

Küçük hücreli dışı akciğer kanseri nedeni ile opere
edilen ileri yaşlı hastaların demografik özellikler, rezeksiyon tipi, sağkalım,
erken ve geç post-op komplikasyonlar, hastanede yatış süresi açısından daha
genç yaş grubu ile karşılaştırılarak ileri yaşın opere edilebilirlik üzerindeki
etkisi araştırılmıştır.

GereçveYöntem

Kocaeli Üniversitesi Tıp Fakültesi Göğüs Cerrahisi
Anabilim Dalı tarafından küçük hücreli dışı akciğer kanseri nedeni ile
rezeksiyon yapılan 288 hasta incelendi. Verileri yeterli görülen hastalar
arasından 70 yaş altı (Grup I – Kontrol Grubu) 244 hasta ve 70 yaş ve üzeri
(ileri yaş) (Grup II – Çalışma Grubu) 44 hasta hasta geriye dönük olarak
incelendi.

Bulgular

Her iki grup arasında hastaların özgeçmişi (p=0,083)
ve rezeksiyon tipi (p=0,557) açısından istatistiksel olarak anlamlı fark
gözlenmedi. Her iki grup arasında sağkalım açısından istatistiksel olarak
anlamlı fark gözlendi (p=0,013). Her iki grup arasında post operatif erken
komplikasyon açısından istatistiksel olarak anlamlı fark görülmezken (p=0,514)
post operatif geç komplikasyon açısından istatistiksel olarak anlamlı fark
gözlendi (p=0,034). Her iki grup arasında post operatif taburculuk süresi
açısından istatistiksel olarak anlamlı fark gözlenmedi (p=0,916).

Sonuç

Çalışmamızda elde ettiğimiz sonuçlara göre; küçük
hücreli dışı akciğer kanseri nedeni ile opere edilmiş ileri yaş hastaların genç
hastalar ile benzer demografik özelliklerde olduğu, post-operatif morbidite ve
cerrahi tedavi sonuçlarında istatistiksel olarak kısmen anlamlı farklar görülse
de büyük oranda benzer olduğu saptanmıştır. Cerrahi tedavi için ileri yaşın tek
başına kontraendikasyon teşkil etmediği sonucuna varılmıştır.

Keywords

İleri yaş, Akciğer kanseri, Cerrahi

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