Research Article
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Year 2023, , 504 - 511, 30.06.2023
https://doi.org/10.16984/saufenbilder.1209954

Abstract

References

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  • C. A. Rynders, E. A. Thomas, A. Zaman, Z. Pan, V. A. Catenacci, E. L. Melanson, “Effectiveness of intermittent fasting and time-restricted feeding compared to continuous energy restriction for weight loss,” Nutrients, vol. 11, no. 10, p. 2442, 2019.
  • H. T. Teker, T. Ceylani, “Intermittent fasting supports the balance of the gut microbiota composition,” International Microbiology, vol. 26, no. 1, pp. 51-57, 2022.
  • T. Ceylani, H. T. Teker, G. Samgane, R. Gurbanov, “Intermittent fasting-induced biomolecular modifications in rat tissues detected by ATR-FTIR spectroscopy and machine learning algorithms,” Analitical Biochemistry, vol. 654, no. 114825, p. 114825, 2022.
  • İ. Ardahanlı, H. İ. Özkan, F. Özel, R. Gurbanov, H. T. Teker, T. Ceylani, “Infrared spectrochemical findings on intermittent fasting-associated gross molecular modifications in rat myocardium,” Biophysical Chemistry, vol. 289, no. 106873, p. 106873, 2022.
  • R. Gurbanov, F. Yıldız, “Molecular Profile of Oral Probiotic Bacteria To Be Used With Functional Foods,” Journal of Food and Health Science, vol. 12, no. 11, pp. S117-31, 2017.
  • C. Aksoy, F. Severcan, “Infrared spectroscopy and imaging in stem cells and aging research,” Methods in Molecular Biology, vol. 2045, pp. 201–215, 2019.
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  • D. R. Whelan, K. R. Bambery, P. Heraud, M. J. Tobin, M. Diem, D. McNaughton, B. R. Wood, “Monitoring the reversible B to A-like transition of DNA in eukaryotic cells using Fourier transform infrared spectroscopy,” Nucleic Acids Research, vol. 39, no. 13, pp. 5439–5448, 2011.
  • T. Liu, T. Yu, S. Zhang, Y. Wang, W. Zhang, “Thermodynamic and kinetic properties of a single base pair in A-DNA and B-DNA,” Physical Review, vol. 103, no. 4–1, p. 042409, 2021.
  • M. Kulkarni, A. Mukherjee, “Understanding B-DNA to A-DNA transition in the right-handed DNA helix: Perspective from a local to global transition,” Progress İn Biophysics And Molecular Biology, vol. 128, pp. 63–73, 2017.
  • N. Pastor, “The B- to A-DNA transition and the reorganization of solvent at the DNA surface,” Biophysical Journal, vol. 88, no. 5, pp. 3262–3275, 2005.
  • N. S. Mehanna, Z. M. R. Hassan, H. M. F. El-Din, A. A. E. Ali, R. Amarowicz, T. M. El-Messery, “Effect of interaction phenolic compounds with milk proteins on cell line,” Food and Nutrition Science, vol. 05, no. 22, pp. 2130–2146, 2014.
  • L. B. Dreier, M. Bonn, E. H. G. Backus, “Hydration and orientation of carbonyl groups in oppositely charged lipid monolayers on water,” The Journal Of Physical Chemistry, vol. 123, no. 5, pp. 1085–1089, 2019.
  • A. Dicko, H. Bourque, M. Pézolet, “Study by infrared spectroscopy of the conformation of dipalmitoylphosphatidylglycerol monolayers at the air–water interface and transferred on solid substrates,” Chemistry and Physics of Lipids, vol. 96, no. 1–2, pp. 125–139, 1998.
  • C.-R. Lee, Y. H. Park, H. Min, Y. R. Kim, Y. J. Seok, “Determination of protein phosphorylation by polyacrylamide gel electrophoresis,” Journal Of Microbiology, vol. 57, no. 2, pp. 93–100, 2019.
  • R. Wang, G. Wang, “Protein modification and autophagy activation,” Advances In Experimental Medicine And Biology, vol. 1206, pp. 237–259, 2019.
  • M. L. R. Paraboni, J. Kalinoski, B. G. Braciak, A. E. Wilk, L. S. Santos, E. G. Schmitt, V. Manfredini, I.L. Gonçalves, “Protein carbonyl products, malondialdehyde, glutathione and vitamins C/E of breast cancer patients subjected to chemotherapy,” Brazilian Journal of Oncology, vol. 18, e20220302, 2022.
  • E. M. De Waal, H. Liang, A. Pierce, R. T. Hamilton, R. Buffenstein, A. R. Chaudhuri, “Elevated protein carbonylation and oxidative stress do not affect protein structure and function in the long-living naked-mole rat: a proteomic approach,” Biochemical And Biophysical Research Communications, vol. 434, no. 4, pp. 815–819, 2013.
  • S. Ballweg, E. Sezgin, M. Doktorova, R. Covino, J. Reinhard, D. Wunnicke, I. Hänelt, I. Levental, G. Hummer, R. Ernst, “Regulation of lipid saturation without sensing membrane fluidity,” Nature Communications, vol. 11, no. 1, p. 756, 2020.
  • B. Szalontai, Y. Nishiyama, Z. Gombos, N. Murata, “Membrane dynamics as seen by Fourier transform infrared spectroscopy in a cyanobacterium, Synechocystis PCC 6803,” Biochimica Et Biophysica Acta, vol. 1509, no. 1–2, pp. 409–419, 2000.
  • A. Paoli, G. Tinsley, A. Bianco, and T. Moro, “The influence of meal frequency and timing on health in humans: The role of fasting,” Nutrients, vol. 11, no. 4, p. 719, 2019.

Aortic Regeneration is Promoted by Intermittent Fasting in Aged Rats

Year 2023, , 504 - 511, 30.06.2023
https://doi.org/10.16984/saufenbilder.1209954

Abstract

Intermittent fasting (IF) plays important role in health. The regeneration that starts at the cellular level is reflected in all tissues and organs. In this study, molecular changes in the aortic tissue of 12-month-old male Wistar rats that underwent intermittent fasting for 18 hours a day for 35 days were determined by spectrochemical analysis and machine learning algoritm. While IF did not significantly affect body weights or blood glucose levels, it led to increased food and water consumption. Spectrochemical analysis revealed significant differences in the forms of DNA, specifically an increase in the A-DNA form in aortic samples. This form of DNA plays an essential role in cellular defense systems and biological processes. There was also an increase in the Amid I band, providing information about hydration status and lipid molecule interactions. Notably, a significant decrease was observed in protein phosphorylation markers, which could impact a wide range of cellular activities. IF also led to reductions in protein carbonylation, a marker of oxidative damage, and changes in the acyl chain length of fatty acids, impacting membrane fluidity. These findings suggest that IF may offer several health benefits, including improved membrane dynamics, reduced oxidative stress, and potential cellular regeneration through autophagy. Further research is needed to confirm these observations and understand their implications for human health.

References

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  • A. C. Milin, G. Vorobiof, O. Aksoy, R. Ardehali, “Insights into aortic sclerosis and its relationship with coronary artery disease,” Journal of the American Heart Association, vol. 3, no. 5, p. e001111, 2014.
  • A. D. Caballero, S. Laín, “A review on computational fluid dynamics modelling in human thoracic aorta,” Cardiovascular Engineering and Technology, vol. 4, no. 2, pp. 103–130, 2013.
  • A. Harloff, J. Simon, S. Brendecke, D. Assefa, T. Helbing, A. Frydrychowicz, J. Weber, M. Olschewski, C. Strecker, J. Hennig, C. Weiller, M. Markl, “Complex plaques in the proximal descending aorta: an underestimated embolic source of stroke: An underestimated embolic source of stroke,” Stroke, vol. 41, no. 6, pp. 1145–1150, 2010.
  • G. Li, C. Xie, S. Lu, R. G. Nichols, Y. Tian, L. Li, D. Patel, Y. Ma, Brocker, N. C. T. Yan, K. W. Krausz, R. Xiang, O. Gavrilova, A. D. Patterson, F. J. Gonzalez, “Intermittent fasting promotes white adipose browning and decreases obesity by shaping the gut Microbiota,” Cell Metabolism, vol. 26, no. 4, pp. 672-685.e4, 2017.
  • C. A. Rynders, E. A. Thomas, A. Zaman, Z. Pan, V. A. Catenacci, E. L. Melanson, “Effectiveness of intermittent fasting and time-restricted feeding compared to continuous energy restriction for weight loss,” Nutrients, vol. 11, no. 10, p. 2442, 2019.
  • H. T. Teker, T. Ceylani, “Intermittent fasting supports the balance of the gut microbiota composition,” International Microbiology, vol. 26, no. 1, pp. 51-57, 2022.
  • T. Ceylani, H. T. Teker, G. Samgane, R. Gurbanov, “Intermittent fasting-induced biomolecular modifications in rat tissues detected by ATR-FTIR spectroscopy and machine learning algorithms,” Analitical Biochemistry, vol. 654, no. 114825, p. 114825, 2022.
  • İ. Ardahanlı, H. İ. Özkan, F. Özel, R. Gurbanov, H. T. Teker, T. Ceylani, “Infrared spectrochemical findings on intermittent fasting-associated gross molecular modifications in rat myocardium,” Biophysical Chemistry, vol. 289, no. 106873, p. 106873, 2022.
  • R. Gurbanov, F. Yıldız, “Molecular Profile of Oral Probiotic Bacteria To Be Used With Functional Foods,” Journal of Food and Health Science, vol. 12, no. 11, pp. S117-31, 2017.
  • C. Aksoy, F. Severcan, “Infrared spectroscopy and imaging in stem cells and aging research,” Methods in Molecular Biology, vol. 2045, pp. 201–215, 2019.
  • E. Dinç, “Kemometri Çok Değişkenli Kalibrasyon Yöntemleri,” Hacettepe Üniversitesi Eczac Fakültesi Dergisi, vol. 39, pp. 46–58, 2007.
  • M. P. Mattson, V. D. Longo, M. Harvie, “Impact of intermittent fasting on health and disease processes,” Ageing Research Reviews, vol. 39, pp. 46–58, 2017.
  • M. Banyay, M. Sarkar, A. Gräslund, “A library of IR bands of nucleic acids in solution,” Biophysical Chemistry, vol. 104, no. 2, pp. 477–488, 2003.
  • D. R. Whelan, K. R. Bambery, P. Heraud, M. J. Tobin, M. Diem, D. McNaughton, B. R. Wood, “Monitoring the reversible B to A-like transition of DNA in eukaryotic cells using Fourier transform infrared spectroscopy,” Nucleic Acids Research, vol. 39, no. 13, pp. 5439–5448, 2011.
  • T. Liu, T. Yu, S. Zhang, Y. Wang, W. Zhang, “Thermodynamic and kinetic properties of a single base pair in A-DNA and B-DNA,” Physical Review, vol. 103, no. 4–1, p. 042409, 2021.
  • M. Kulkarni, A. Mukherjee, “Understanding B-DNA to A-DNA transition in the right-handed DNA helix: Perspective from a local to global transition,” Progress İn Biophysics And Molecular Biology, vol. 128, pp. 63–73, 2017.
  • N. Pastor, “The B- to A-DNA transition and the reorganization of solvent at the DNA surface,” Biophysical Journal, vol. 88, no. 5, pp. 3262–3275, 2005.
  • N. S. Mehanna, Z. M. R. Hassan, H. M. F. El-Din, A. A. E. Ali, R. Amarowicz, T. M. El-Messery, “Effect of interaction phenolic compounds with milk proteins on cell line,” Food and Nutrition Science, vol. 05, no. 22, pp. 2130–2146, 2014.
  • L. B. Dreier, M. Bonn, E. H. G. Backus, “Hydration and orientation of carbonyl groups in oppositely charged lipid monolayers on water,” The Journal Of Physical Chemistry, vol. 123, no. 5, pp. 1085–1089, 2019.
  • A. Dicko, H. Bourque, M. Pézolet, “Study by infrared spectroscopy of the conformation of dipalmitoylphosphatidylglycerol monolayers at the air–water interface and transferred on solid substrates,” Chemistry and Physics of Lipids, vol. 96, no. 1–2, pp. 125–139, 1998.
  • C.-R. Lee, Y. H. Park, H. Min, Y. R. Kim, Y. J. Seok, “Determination of protein phosphorylation by polyacrylamide gel electrophoresis,” Journal Of Microbiology, vol. 57, no. 2, pp. 93–100, 2019.
  • R. Wang, G. Wang, “Protein modification and autophagy activation,” Advances In Experimental Medicine And Biology, vol. 1206, pp. 237–259, 2019.
  • M. L. R. Paraboni, J. Kalinoski, B. G. Braciak, A. E. Wilk, L. S. Santos, E. G. Schmitt, V. Manfredini, I.L. Gonçalves, “Protein carbonyl products, malondialdehyde, glutathione and vitamins C/E of breast cancer patients subjected to chemotherapy,” Brazilian Journal of Oncology, vol. 18, e20220302, 2022.
  • E. M. De Waal, H. Liang, A. Pierce, R. T. Hamilton, R. Buffenstein, A. R. Chaudhuri, “Elevated protein carbonylation and oxidative stress do not affect protein structure and function in the long-living naked-mole rat: a proteomic approach,” Biochemical And Biophysical Research Communications, vol. 434, no. 4, pp. 815–819, 2013.
  • S. Ballweg, E. Sezgin, M. Doktorova, R. Covino, J. Reinhard, D. Wunnicke, I. Hänelt, I. Levental, G. Hummer, R. Ernst, “Regulation of lipid saturation without sensing membrane fluidity,” Nature Communications, vol. 11, no. 1, p. 756, 2020.
  • B. Szalontai, Y. Nishiyama, Z. Gombos, N. Murata, “Membrane dynamics as seen by Fourier transform infrared spectroscopy in a cyanobacterium, Synechocystis PCC 6803,” Biochimica Et Biophysica Acta, vol. 1509, no. 1–2, pp. 409–419, 2000.
  • A. Paoli, G. Tinsley, A. Bianco, and T. Moro, “The influence of meal frequency and timing on health in humans: The role of fasting,” Nutrients, vol. 11, no. 4, p. 719, 2019.
There are 28 citations in total.

Details

Primary Language English
Subjects Structural Biology
Journal Section Research Articles
Authors

Hikmet Taner Teker 0000-0002-6621-3071

Taha Ceylani 0000-0002-3041-6010

Early Pub Date June 22, 2023
Publication Date June 30, 2023
Submission Date November 25, 2022
Acceptance Date February 18, 2023
Published in Issue Year 2023

Cite

APA Teker, H. T., & Ceylani, T. (2023). Aortic Regeneration is Promoted by Intermittent Fasting in Aged Rats. Sakarya University Journal of Science, 27(3), 504-511. https://doi.org/10.16984/saufenbilder.1209954
AMA Teker HT, Ceylani T. Aortic Regeneration is Promoted by Intermittent Fasting in Aged Rats. SAUJS. June 2023;27(3):504-511. doi:10.16984/saufenbilder.1209954
Chicago Teker, Hikmet Taner, and Taha Ceylani. “Aortic Regeneration Is Promoted by Intermittent Fasting in Aged Rats”. Sakarya University Journal of Science 27, no. 3 (June 2023): 504-11. https://doi.org/10.16984/saufenbilder.1209954.
EndNote Teker HT, Ceylani T (June 1, 2023) Aortic Regeneration is Promoted by Intermittent Fasting in Aged Rats. Sakarya University Journal of Science 27 3 504–511.
IEEE H. T. Teker and T. Ceylani, “Aortic Regeneration is Promoted by Intermittent Fasting in Aged Rats”, SAUJS, vol. 27, no. 3, pp. 504–511, 2023, doi: 10.16984/saufenbilder.1209954.
ISNAD Teker, Hikmet Taner - Ceylani, Taha. “Aortic Regeneration Is Promoted by Intermittent Fasting in Aged Rats”. Sakarya University Journal of Science 27/3 (June 2023), 504-511. https://doi.org/10.16984/saufenbilder.1209954.
JAMA Teker HT, Ceylani T. Aortic Regeneration is Promoted by Intermittent Fasting in Aged Rats. SAUJS. 2023;27:504–511.
MLA Teker, Hikmet Taner and Taha Ceylani. “Aortic Regeneration Is Promoted by Intermittent Fasting in Aged Rats”. Sakarya University Journal of Science, vol. 27, no. 3, 2023, pp. 504-11, doi:10.16984/saufenbilder.1209954.
Vancouver Teker HT, Ceylani T. Aortic Regeneration is Promoted by Intermittent Fasting in Aged Rats. SAUJS. 2023;27(3):504-11.

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