Development of an Analytical Method for the Determination of Cymoxanil in Potato Flour Samples by High Performance Liquid Chromatography

Year 2023, , 1002 - 1007, 18.10.2023

Tuğçe Unutkan Gösterişli

https://doi.org/10.16984/saufenbilder.1265507

Abstract

In this study, a high performance liquid chromatography-ultraviolet detection method was introduced for the detection of cymoxanil. The experimental parameters of the procedure were thoroughly evaluated. Cymoxanil was eluted by ammonium formate buffer (50.0 mM, pH 4.0):acetonitrile (55:45 v/v) as mobile phase. Under the optimal conditions, the limits of detection and quantification (LOD and LOQ) were found as 7.4 – 24.8 µg kg-1, which allows trace determination of pesticides in food samples. Proposed method was then implemented for the determination of selected fungicide in potato flour samples with acceptable % recoveries in the range of 81.4–112.9%, while the values of relative standard deviation (RSD) were below 10% showing a satisfactory applicability for cymoxanil in such complex real samples matrix.

Keywords

Cymoxanil, potato flour, high performance liquid chromatography, fungidice

References

• F. M. Al-Nasir, A. G. Jiries, G. J. Al-Rabadi, M. H. Alu'datt, C. C. Tranchant, S. A. Al-Dalain, N. Alrabadi, O. Y. Madanat, R. S. Al-Dmour, "Determination of pesticide residues in selected citrus fruits and vegetables cultivated in the Jordan Valley" LWT, vol. 123, pp. 109005, 2020.
• A. Abbasalizadeh, S. M. Sorouraddin, M. A. Farajzadeh, M. Nemati, M. R. A. Mogoddam, "Dispersive solid phase extraction of several pesticides from fruit juices using a hydrophobic metal organic framework prior to HPLC-MS/MS determination" Journal of Food Composition and Analysis, vol. 114, pp. 104788, 2022.
• H. Serbest, "Determination of Resmethrin in Corn Silk Matrix by Gas Chromatography-Flame Ionization Detector (GC-FID)" Sakarya University Journal of Science, vol. 26(5), pp. 1022-1028, 2022.
• S. Amini, M. Amiri, H. Ebrahimzadeh, S. Seidi, S. H. kandeh, "Synthesis of magnetic Cu/CuFe2O4@ MIL-88A (Fe) nanocomposite and application to dispersive solid-phase extraction of chlorpyrifos and phosalone in water and food samples" Journal of Food Composition and Analysis, vol. 104, pp. 104128, 2021.
• R.C. Gilden, K. Huffling, B. Sattler, "Pesticides and health risks" Journal of Obstetric, Gynecologic & Neonatal Nursing, vol. 39(1), pp. 103-110, 2010.
• K. -H. Kim, E. Kabir, S. A. Jahan, "Exposure to pesticides and the associated human health effects" Science of the total environment, vol. 575, pp. 525-535, 2017.
• V. Feigenbrugel, S. Le Calvé, P. Mirabel, "Molar absorptivities of 2, 4-D, cymoxanil, fenpropidin, isoproturon and pyrimethanil in aqueous solution in the near-UV" Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, vol. 63(1), pp. 103-110, 2006.
• J. -Y. Yoon, J. E. Kim, H. J. Song, K. B. Oh, J. W. Jo, Y. -H. Yang, S. H. Lee, G. Kang, H. J. Kim, Y. -K. Choi, "Assessment of adsorptive behaviors and properties of grape pomace-derived biochar as adsorbent for removal of cymoxanil pesticide" Environmental Technology & Innovation, vol. 21, pp. 101242, 2021.
• X. Jiang, H. Jin, Y. Sun, R. Gui, "Colorimetric and fluorometric dual-channel ratiometric determination of fungicide cymoxanil based on analyte-induced aggregation of silver nanoparticles and dually emitting carbon dots" Microchimica Acta, vol. 186, pp. 1-12, 2019.
• H. Mercan, R. Inam, "Determination of Cymoxanil Fungicide in Commercial Formulation and Natural Water by Square‐wave Stripping Voltammetry" CLEAN–Soil, Air, Water, vol. 38(5‐6), pp. 558-564, 2010.
• P. Fidente, C. D. Giovanni, S. Seccia, P. Morrica, "Determination of cymoxanil in drinking water and soil using high‐performance liquid chromatography" Biomedical Chromatography, vol. 19(10), pp. 766-770, 2005.
• A. S. TP, K. Banerjee, M. Jadhav, R. Girame, S. Utture, S. Hingmire, D. Oulkar, "Residue dissipation and processing factor for dimethomorph, famoxadone and cymoxanil during raisin preparation" Food chemistry, vol. 170, pp. 180-185, 2015.
• M. J. Hengel, T. Shibamoto, "Development of a gas chromatographic method for fungicide cymoxanil analysis in dried hops" Journal of agricultural and food chemistry, vol. 49(2), pp. 570-573, 2001.
• D. Bavol, J. Zima, J. Barek, H. Dejmkova, "Voltammetric determination of cymoxanil and famoxadone at different types of carbon electrodes" Electroanalysis, vol. 28(5), pp. 1029-1034, 2016.
• K. Dost, M. Öksüz, M. Cittan, B. Mutlu, B. Tural, "Determination of boscalid, pyraclostrobin and trifloxystrobin in dried grape and apricot by HPLC/UV method" Journal of Food Composition and Analysis, vol. 115, pp. 104926, 2023.
• R. R. Pasupuleti, Z. -F. Wang, W. -J. Ya, C. -A. Kuo, Y. -Y Chao, Y. -L. Huang, "Extraction and detection of chlorophenols in water samples using deep eutectic solvent-based dispersive liquid–liquid microextraction coupled with HPLC-UV" Microchemical Journal, vol. 182, pp. 107843, 2022.