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Measurement of the Penetration Depth in Biological Tissue for Different Optical Powers

Year 2018, , 1095 - 1100, 01.08.2018
https://doi.org/10.16984/saufenbilder.332802

Abstract

In photodynamic therapy, the knowledge of the penetration depth for the
light is needed in order to ensure that the optical energy received by the
tumorous tissue. In this study, the optical penetration depths of 635 nm laser
light in chicken breast tissue have been measured by using 8 tissue samples
with different thicknesses between 2.5 mm and 9.0 mm. Transmitted light
intensities through the tissue samples have been measured with 11 different
optical power values in the range of 130mW – 660mW. Measurement results for
each power value have been analyzed according to the Beer-Lambert law. With the
help of statistical analyzes, it has been determined that the optical
penetration depth of the light in biological tissue does not depend on its
optical power.

References

  • T.J. Dougherty, C.J. Gomer, B.W. Henderson et al., “Photodynamic Therapy”, J Natl Cancer Inst., 90(12), pp. 889–905, 1998.
  • A.P. Castano, T.N. Demidova, and M.R. Hamblin, “Mechanisms in photodynamic therapy: part one—-photosensitizers, photochemistry and cellular localization”, Photodiagnosis Photodyn Ther., 1(4), pp. 279–293, 2004.
  • L. Grossweiner, “Light dosimetry model for photodynamic therapy treatment planning”, Lasers Surg Med., 11(2), pp. 165-173, 1991.
  • T.C. Zhu and J.C. Finlay, “The role of photodynamic therapy (PDT) physics”, Med Phys., 35(7), pp. 3127–3136, 2008.
  • Z. Huang, H. Xu, A.D. Meyers et al. “Photodynamic therapy for treatment of solid tumors – potential and technical challenges”, Technology in Cancer Research & Treatment, 7(4), pp. 309–320, 2008.
  • M.R. Arnfield, J.D. Chapman, J. Tulip, M.C. Fenning and M.S. McPhee, “Optical properties of experimental prostate tumors in vivo”, Photochem. Photobiol., 57(2), pp. 306-311, 1993.
  • S. Stolik, J.A. Delgado, A. Pe´rez and L. Anasagasti, “Measurement of the penetration depths of red and near infrared light in human ex vivo tissues”, J. Photochem. Photobiol. B, Biol., 57, pp. 90-93, 2000.
  • Y.B. Dolugan, H. Arslan, M.Z. Yıldız, A.E. Ozdemir, A.F. Kamanlı and A.N. Ay, “Measurement of the optical penetration depth in chicken breast tissue” in Proceedings of the 5th International Conference on Advanced Technology & Sciences, 2017, pp. 222–222.
  • H. Kolarova, D. Ditrichova and J. Wagner, “Penetration of the Laser Light Into the Skin In Vitro”, Lasers in Surgery and Medicine, 24, pp. 231–235, 1999.
  • D.C. Shackley, C. Whitehurst, J.V. Moore, N.J.R. George, C.D. Betts And N.W. Clarke, “Light penetration in bladder tissue: implications for the intravesical photodynamic therapy of bladder tumours”, BJU International, 86, pp. 638-643, 2000.
  • B.C. Wilson and G. Adam, “A Monte Carlo model for the absorption and flux distributions of light in tissue”, Med Phys., 10(6), 824–830, 1983.
  • H. Arslan, “Simulation Study for the Penetration Depth of Red and Near Infrared Light in Muscle Tissue” in Proceedings of the 4th International Symposium on Innovative Technologies in Engineering and Science, 2016, pp. 329–333.
  • A. Abdo, A. Ersen, and M. Sahin, “Near-infrared light penetration profile in the rodent brain”, Journal of Biomedical Optics, 18(7), 075001, 2013.
  • H.S. Lim, “Reduction of thermal damage in photodynamic therapy by laser irradiation techniques”, Journal of Biomedical Optics, 17(12), 128001, 2012.
  • Statistics Solutions. (2013). ANOVA Retrieved from: http://www.statisticssolutions.com/academic-solutions/resources/directory-of-statistical-analyses/anova/
  • G. Cetinel, L. Cerkezi, “Wavelet Based Medical Image Watermarking Scheme for Patient Information Authenticity”, International Journal of Aplied Mathematics, Electronics and Computers, 2016.
  • P. A. Katyayan, M. K. Katyayan, “Effect of smoking status and nicotine dependence on pain intensity and outcome of treatment in Indian patients with temporomandibular disorders: A longitudinal cohort study”, The Journal of Indian Prosthodontic Society, 2017.
  • A. Ay, M. Z. Yildiz, B. Boru, “Real-time feature extraction of ECG signals using NI LabVIEW”, Sakarya University Journal of Science,10.16984/saufenbilder.287418, 2017.
  • G. Marquez et al., “Anisotropy in the absorption and scattering spectra of chicken breast tissue”, Applied Optics, 37(4), 798-804, 1998.
  • Y.B. Dolugan, H. Arslan, et al., “Measurement of the optical penetration depth in chicken breast tissue” in Proceedings of the 5th International Conference on Advanced Technology & Sciences, pp. 222–222, 2017.
  • H.P. Berlien, G.J. Müller, “Applied Laser Medicine”, Springer Science & Business Media, pp. 384, 2012.

Biyolojik Dokulardaki Penetrasyon Derinliklerinin Farklı Optik Güç Değerleri İçin Ölçülmesi

Year 2018, , 1095 - 1100, 01.08.2018
https://doi.org/10.16984/saufenbilder.332802

Abstract



Fotodinamik Terapi’de (PDT), tümörlü doku tarafından alınan
optik enerjinin yeterli olup olmadığının belirlenebilmesi için ışığın doku
içindeki penetrasyon derinliğinin bilinmesi gereklidir. Bu çalışmada, 635 nm
lazer ışığının tavuk göğsü dokusundaki penetrasyon derinliği 2.5 mm ile 9.0 mm
arasında değişen farklı kalınlıklarda 8 doku örneği kullanılarak ölçülmüştür. Doku
örneklerinde iletilen ışık yoğunlukları 130mW – 660mW aralığındaki 11 farklı
optik güç değeri için ölçülmüştür. Her bir güç değeri için ölçüm sonuçları
Beer-Lambert yasasına göre analiz edilmiştir. İstatistiksel analizler
yardımıyla, biyolojik dokudaki penetrasyon derinliğinin optiksel güce bağlı
olmadığı saptanmıştır.

References

  • T.J. Dougherty, C.J. Gomer, B.W. Henderson et al., “Photodynamic Therapy”, J Natl Cancer Inst., 90(12), pp. 889–905, 1998.
  • A.P. Castano, T.N. Demidova, and M.R. Hamblin, “Mechanisms in photodynamic therapy: part one—-photosensitizers, photochemistry and cellular localization”, Photodiagnosis Photodyn Ther., 1(4), pp. 279–293, 2004.
  • L. Grossweiner, “Light dosimetry model for photodynamic therapy treatment planning”, Lasers Surg Med., 11(2), pp. 165-173, 1991.
  • T.C. Zhu and J.C. Finlay, “The role of photodynamic therapy (PDT) physics”, Med Phys., 35(7), pp. 3127–3136, 2008.
  • Z. Huang, H. Xu, A.D. Meyers et al. “Photodynamic therapy for treatment of solid tumors – potential and technical challenges”, Technology in Cancer Research & Treatment, 7(4), pp. 309–320, 2008.
  • M.R. Arnfield, J.D. Chapman, J. Tulip, M.C. Fenning and M.S. McPhee, “Optical properties of experimental prostate tumors in vivo”, Photochem. Photobiol., 57(2), pp. 306-311, 1993.
  • S. Stolik, J.A. Delgado, A. Pe´rez and L. Anasagasti, “Measurement of the penetration depths of red and near infrared light in human ex vivo tissues”, J. Photochem. Photobiol. B, Biol., 57, pp. 90-93, 2000.
  • Y.B. Dolugan, H. Arslan, M.Z. Yıldız, A.E. Ozdemir, A.F. Kamanlı and A.N. Ay, “Measurement of the optical penetration depth in chicken breast tissue” in Proceedings of the 5th International Conference on Advanced Technology & Sciences, 2017, pp. 222–222.
  • H. Kolarova, D. Ditrichova and J. Wagner, “Penetration of the Laser Light Into the Skin In Vitro”, Lasers in Surgery and Medicine, 24, pp. 231–235, 1999.
  • D.C. Shackley, C. Whitehurst, J.V. Moore, N.J.R. George, C.D. Betts And N.W. Clarke, “Light penetration in bladder tissue: implications for the intravesical photodynamic therapy of bladder tumours”, BJU International, 86, pp. 638-643, 2000.
  • B.C. Wilson and G. Adam, “A Monte Carlo model for the absorption and flux distributions of light in tissue”, Med Phys., 10(6), 824–830, 1983.
  • H. Arslan, “Simulation Study for the Penetration Depth of Red and Near Infrared Light in Muscle Tissue” in Proceedings of the 4th International Symposium on Innovative Technologies in Engineering and Science, 2016, pp. 329–333.
  • A. Abdo, A. Ersen, and M. Sahin, “Near-infrared light penetration profile in the rodent brain”, Journal of Biomedical Optics, 18(7), 075001, 2013.
  • H.S. Lim, “Reduction of thermal damage in photodynamic therapy by laser irradiation techniques”, Journal of Biomedical Optics, 17(12), 128001, 2012.
  • Statistics Solutions. (2013). ANOVA Retrieved from: http://www.statisticssolutions.com/academic-solutions/resources/directory-of-statistical-analyses/anova/
  • G. Cetinel, L. Cerkezi, “Wavelet Based Medical Image Watermarking Scheme for Patient Information Authenticity”, International Journal of Aplied Mathematics, Electronics and Computers, 2016.
  • P. A. Katyayan, M. K. Katyayan, “Effect of smoking status and nicotine dependence on pain intensity and outcome of treatment in Indian patients with temporomandibular disorders: A longitudinal cohort study”, The Journal of Indian Prosthodontic Society, 2017.
  • A. Ay, M. Z. Yildiz, B. Boru, “Real-time feature extraction of ECG signals using NI LabVIEW”, Sakarya University Journal of Science,10.16984/saufenbilder.287418, 2017.
  • G. Marquez et al., “Anisotropy in the absorption and scattering spectra of chicken breast tissue”, Applied Optics, 37(4), 798-804, 1998.
  • Y.B. Dolugan, H. Arslan, et al., “Measurement of the optical penetration depth in chicken breast tissue” in Proceedings of the 5th International Conference on Advanced Technology & Sciences, pp. 222–222, 2017.
  • H.P. Berlien, G.J. Müller, “Applied Laser Medicine”, Springer Science & Business Media, pp. 384, 2012.
There are 21 citations in total.

Details

Subjects Metrology, Applied and Industrial Physics, Electrical Engineering
Journal Section Research Articles
Authors

Halil Arslan

Yaşar Barış Doluğan

Ayşe Nur Ay This is me

Publication Date August 1, 2018
Submission Date August 4, 2017
Acceptance Date November 14, 2017
Published in Issue Year 2018

Cite

APA Arslan, H., Doluğan, Y. B., & Ay, A. N. (2018). Measurement of the Penetration Depth in Biological Tissue for Different Optical Powers. Sakarya University Journal of Science, 22(4), 1095-1100. https://doi.org/10.16984/saufenbilder.332802
AMA Arslan H, Doluğan YB, Ay AN. Measurement of the Penetration Depth in Biological Tissue for Different Optical Powers. SAUJS. August 2018;22(4):1095-1100. doi:10.16984/saufenbilder.332802
Chicago Arslan, Halil, Yaşar Barış Doluğan, and Ayşe Nur Ay. “Measurement of the Penetration Depth in Biological Tissue for Different Optical Powers”. Sakarya University Journal of Science 22, no. 4 (August 2018): 1095-1100. https://doi.org/10.16984/saufenbilder.332802.
EndNote Arslan H, Doluğan YB, Ay AN (August 1, 2018) Measurement of the Penetration Depth in Biological Tissue for Different Optical Powers. Sakarya University Journal of Science 22 4 1095–1100.
IEEE H. Arslan, Y. B. Doluğan, and A. N. Ay, “Measurement of the Penetration Depth in Biological Tissue for Different Optical Powers”, SAUJS, vol. 22, no. 4, pp. 1095–1100, 2018, doi: 10.16984/saufenbilder.332802.
ISNAD Arslan, Halil et al. “Measurement of the Penetration Depth in Biological Tissue for Different Optical Powers”. Sakarya University Journal of Science 22/4 (August 2018), 1095-1100. https://doi.org/10.16984/saufenbilder.332802.
JAMA Arslan H, Doluğan YB, Ay AN. Measurement of the Penetration Depth in Biological Tissue for Different Optical Powers. SAUJS. 2018;22:1095–1100.
MLA Arslan, Halil et al. “Measurement of the Penetration Depth in Biological Tissue for Different Optical Powers”. Sakarya University Journal of Science, vol. 22, no. 4, 2018, pp. 1095-00, doi:10.16984/saufenbilder.332802.
Vancouver Arslan H, Doluğan YB, Ay AN. Measurement of the Penetration Depth in Biological Tissue for Different Optical Powers. SAUJS. 2018;22(4):1095-100.

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