A Clinical Trial of The Evaluation of Environmental Exposure in Yttrium 90 Radioembolization

Year 2018, , 1820 - 1827, 01.12.2018

Handan Tanyildizi , İffet Çavdar , Mustafa Demir

https://doi.org/10.16984/saufenbilder.418634

Abstract

Aim: The aim of this study is to measure the dose rate of two
different forms of Y-90 microsphere used for radioembolization and to evaluate
the results according to radiation safety regularities. Material and Methods:
19 patients were enrolled in study (Age:61±1.5, F/M:12/7). As a result of the
evaluation of the physicians, 7 patients were treated with TheraSphere and 12
patients were treated with SIR-Sphere. Dose rate measurements were taken at the
stage of activity preparation, injection, radioactive wastes and discharge of
patients via electronic dosimeter (ED). Results: The staff was exposed to dose
rate of 1,3.10^-4 μSv/MBq.h during activity preparation stage,  2,4.10^-4 μSv/MBq.h in injection
stage for Therapshere application. For SIR-spheres application, the staff was
exposed to dose rate of 24,5.10^-4 μSv/MBq.h during activity preparation
stage, 10,1.10^-4 μSv/MBq.h in injection stage. The average amount of
dose received per operation was calculated 0.92±0.48 μSv in TheraSphere and
3.22±0.89 μSv in SIR-Spheres. For discharge of the patients, the average dose
rate recorded from 1 m was found 4±0.28 μGy.h^-1 for TheraSphere and
3.2±0.15 μGy.h^-1 for SIR-Spheres. The dose rate of radioactive
wastes measured from the surface of the container which contained the
radioactive wastes generated after the application was 0.5±0.1 μSv.h^-1
for TheraSphere and 1.1±0.08 μSv.h^-1 for SIR-Spheres. Conclusion: It
is emphasized that Y-90 Therasphere application provides radiation safety more
than SIR-Spheres because of its closed system, even so both applications shows
low dose rate around the patient and short-term storage of radioactive wastes
after application would be sufficient.

Keywords

exposure, radioembolization, yttrium 90, radiation protection

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