In this work, firstly, CeO2 nanoparticles, which can be used as catalysts in many reactions, were synthesized by preparing aqueous solution of cerium(III) nitrate hexahydrate in basic medium. In the second step, the synthesis of dimeric thio Schiff bases was carried out using two different methods. Effect of catalyst on some parameters such as reaction time and yield of product were investigated. The antimicrobial activities of the ligands have been screened in vitro against the organisms Acinetobacter baumannii, Escherichia coli, Klebsiella pneumoniae (Gram negative bacteria), Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, Bacillus cereus (Gram positive bacteria) and Candida albicans, C. tropicalis, C. guilliermondii, C. glabrata by Disc Diffusion and Microdilution methods. At the same time, antimicrobial activities of ligands were compared to standard antibiotics (Cefotaxime, Amoxicillin/clavulanic acid, Posacanazole, Nystatin and Gentamicin). Generally, the results obtained in this research showed that all tested ligands exhibited more effect towards Gram positive bacteria and Candida species as compared to standard antibiotics.
Düzce Üniversitesi
Project No: 2014-05-03-259 and 2015-05-03-354
This research was supported by Duzce University Scientific Research Fund (BAP) (Project No: 2014-05-03-259 and 2015-05-03-354).
Project No: 2014-05-03-259 and 2015-05-03-354
Primary Language | English |
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Subjects | Chemical Engineering |
Journal Section | Research Articles |
Authors | |
Project Number | Project No: 2014-05-03-259 and 2015-05-03-354 |
Publication Date | April 15, 2021 |
Submission Date | May 15, 2020 |
Acceptance Date | February 4, 2021 |
Published in Issue | Year 2021 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.