Research Article
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Year 2021, , 938 - 949, 30.08.2021
https://doi.org/10.16984/saufenbilder.868944

Abstract

References

  • 1. Apak, R., Guclu, K., Ozyurek, M., Karademir, S. E., & Altun, M. (2005). Total antioxidant capacity assay of human serum using copper(II)-neocuproine as chromogenic oxidant: The CUPRAC method. Free Radical Research, 39(9), 949–961. https://doi.org/10.1080/10715 76050 0210145
  • 2. Singleton, V. L., Orthofer, R., & Lamuela-Raventós, R. M. (1998). Analysis of total phenols and other oxidation substrates and antioxidants by means of folin-ciocalteu reagent. Methods in Enzymology, 299, 152–178
  • 3. Arvouet-Grand A, Vennat B, Pourrat A, Legret P. Standardisation d'un extrait de propolis et identification des principaux constituants [Standardization of propolis extract and identification of principal constituents]. J Pharm Belg. 1994 Nov-Dec;49(6):462-8. French. PMID: 7884635.
  • 4. Zeytunluoglu, A., & Zihnioglu, F. (2015). Evaluation of some plants for potential dipeptidyl peptidase IV inhibitory effects in vitro. Turkish Journal of Biochemistry-Turk Biyokimya Dergisi, 40(3), 217–223. https://doi.org/10.1515/tjb.2015.0004
  • 5. T. Matsui, C. Yoshimoto, K. Osajima, T. Oki, Y. Osajima In vitro survey of α-glucosidase inhibitory food components Bioscience, Biotechnology and Biochemistry, 60 (1996), pp. 2019-2022
  • 6. Forbes, J. M., & Fotheringham, A. K. (2017). Vascular complications in diabetes: old messages, new thoughts. Diabetologia, 60(11), 2129-2138. https://doi.org/10.1007/s00125-017-4360-x
  • 7. Cho, N., Shaw, J. E., Karuranga, S., Huang, Y., da Rocha Fernandes, J. D., Ohlrogge, A. W., & Malanda, B. (2018). IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045. Diabetes research and clinical practice, 138, 271-281. https://doi.org/10.1016/j.diabres.2018.02.023
  • 8. Kajaria, D., Ranjana, J. T., Tripathi, Y. B., & Tiwari, S. (2013). In-vitro α amylase and glycosidase inhibitory effect of ethanolic extract of antiasthmatic drug—Shirishadi. Journal of advanced pharmaceutical technology & research, 4(4), 206.
  • 9. Wang, X., Cao, J., Dai, X., Xiao, J., Wu, Y., & Wang, Q. (2017). Total flavonoid concentrations of bryophytes from Tianmu Mountain, Zhejiang Province (China): Phylogeny and ecological factors. PloS one, 12(3), e0173003.
  • 10. ASLANBABA, B., YILMAZ, S., YAYINTAŞ, Ö. T., ÖZYURT, D., & ÖZTÜRK, B. D. (2017). Total phenol content and antioxidant activity of mosses from Yenice forest (Ida mountain). Journal of Scientific Perspectives, 1(1), 1-12.
  • 11. Sethi, S., Joshi, A., Arora, B., Bhowmik, A., Sharma, R. R., & Kumar, P. (2020). Significance of FRAP, DPPH, and CUPRAC assays for antioxidant activity determination in apple fruit extracts. European Food Research and Technology, 246(3), 591-598.
  • 12. McCue, P., Kwon, Y.I., Shetty, K., 2005, Anti-diabetic and anti-hypertensive potential of sprouted and solid-state bioprocessed soybean, Asia Pac J Clin Nutr., 14(2), 145-52.
  • 13. Rahim, F., Zaman, K., Taha, M., Ullah, H., Ghufran, M., Wadood, A., ... & Nawaz, F. (2020). Synthesis, in vitro alpha-glucosidase inhibitory potential of benzimidazole bearing bis-Schiff bases and their molecular docking study. Bioorganic chemistry, 94, 103394.
  • 14. Xiong, Y., Ng, K., Zhang, P., Warner, R. D., Shen, S., Tang, H. Y., ... & Fang, Z. (2020). In Vitro α-Glucosidase and α-Amylase Inhibitory Activities of Free and Bound Phenolic Extracts from the Bran and Kernel Fractions of Five Sorghum Grain Genotypes. Foods, 9(9), 1301.
  • 15. Peng, C.-H., Yang, Y.-S., Chan, K.-C., Wang, C.-J., Chen, M.-L., Huang, C.-N., et al. (2014). Hibiscus sabdariffa polyphenols alleviate insulin resistance and renal epithelial to mesenchymal transition: a novel action mechanism mediated by type 4 dipeptidyl peptidase. J. Agric. Food Chem. 62, 9736–9743. doi: 10.1021/ jf5024092
  • 16. Kalhotra P, Chittepu VCSR, Osorio-Revilla G, Gallardo-Velazquez T. Phytochemicals in Garlic Extract Inhibit Therapeutic Enzyme DPP-4 and Induce Skeletal Muscle Cell Proliferation: A Possible Mechanism of Action to Benefit the Treatment of Diabetes Mellitus. Biomolecules. 2020 Feb 14;10(2):305. doi: 10.3390/biom10020305. PMID: 32075130; PMCID: PMC7072494.
  • 17. Zakłos-Szyda, M., Kowalska-Baron, A., Pietrzyk, N., Drzazga, A., & Podsędek, A. (2020). Evaluation of Viburnum opulus L. Fruit Phenolics Cytoprotective Potential on Insulinoma MIN6 Cells Relevant for Diabetes Mellitus and Obesity. Antioxidants (Basel, Switzerland), 9(5), 433. https://doi.org/10.3390/antiox9050433
  • 18. Fan J, Johnson MH, Lila MA, Yousef G, de Mejia EG. Berry and Citrus Phenolic Compounds Inhibit Dipeptidyl Peptidase IV: Implications in Diabetes Management. Evid Based Complement Alternat Med. 2013;2013:479505. doi: 10.1155/2013/479505. Epub 2013 Aug 29. PMID: 24069048; PMCID: PMC3773436.
  • 19. Ansari, N. A., & Rasheed, Z. (2009). Non-enzymatic glycation of proteins: From diabetes to cancer. Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry, 3(4), 335–342. https://doi.org/10.1134/s1990 75080 9040027
  • 20. Sattarahmady, N., Moosavi-Movahedi, A. A., Ahmad, F., Hakimelahi, G. H., Habibi-Rezaei, M., Saboury, A. A., & Sheibani, N. (2007). Formation of the molten globule-like state during prolonged glycation of human serum albumin. Biochimica et Biophysica Acta (BBA)-General Subjects, 1770(6), 933-942.
  • 21. Christen, Y. (2000). Oxidative stress and Alzheimer disease. The American journal of clinical nutrition, 71(2), 621S-629S
  • 22. Decker, E. L., & Reski, R. (2020). Mosses in biotechnology. Current opinion in biotechnology, 61, 21-27.
  • 23. Li, X., Wang, X., Chen, D., & Chen, S. (2011). Antioxidant activity and mechanism of protocatechuic acid in vitro. Functional Foods in Health and Disease, 1(7), 232. https://doi.org/10.31989/ ffhd.v1i7.127
  • 24. Kani, H. K., Kocazorbaz, E. K., & Zihnioglu, F. (2019). Investigation and isolation of peptide based antiglycating agents from various sources. Turkish Journal of Biochemistry, 44(5), 699-705.
  • 25. Duez, H., Cariou, B., & Staels, B. (2012). DPP-4 inhibitors in the treatment of type 2 diabetes. Biochemical pharmacology, 83(7), 823-832.
  • 26. Dukic-Stefanovic, S., Schinzel, R., Riederer, P., & Münch, G. (2001). AGES in brain ageing: AGE-inhibitors as neuroprotective and anti-dementia drugs?. Biogerontology, 2(1), 19-34.
  • 27. Nawale, R. B., Mourya, V. K., & Bhise, S. B. (2006). Non-enzymatic glycation of proteins: a cause for complications in diabetes.

Phytochemical and Bioactivity Analysis of Several Methanolic Extracts of Nine Bryophytes Species

Year 2021, , 938 - 949, 30.08.2021
https://doi.org/10.16984/saufenbilder.868944

Abstract

Bryophytes are a class of organisms found all over the globe except the sea. They can grow on different surfaces and are known for their fragrant aromas and strong hot and bitter taste. Bryophytes have been used in traditional Chinese medicine for the treatment of many pathological conditions. In the current study, we describe the bioactivities present in methanolic extracts obtained from 9 species of bryophytes. Plant samples were dried and extracted in a water/methanol solution which was explored for flavonoid and phenolic content. Afterwards, the extracts were analyzed for their potential bioactivities including DPP4 inhibition, metal chelation, antioxidant, and antiglycation activities. Results indicate that the methanolic extracts of each species showed high effectiveness for different bioactivities. The current findings suggest these bryophytes as promising source of therapeutics against oxidative stress, hypertension, and diabetes.

References

  • 1. Apak, R., Guclu, K., Ozyurek, M., Karademir, S. E., & Altun, M. (2005). Total antioxidant capacity assay of human serum using copper(II)-neocuproine as chromogenic oxidant: The CUPRAC method. Free Radical Research, 39(9), 949–961. https://doi.org/10.1080/10715 76050 0210145
  • 2. Singleton, V. L., Orthofer, R., & Lamuela-Raventós, R. M. (1998). Analysis of total phenols and other oxidation substrates and antioxidants by means of folin-ciocalteu reagent. Methods in Enzymology, 299, 152–178
  • 3. Arvouet-Grand A, Vennat B, Pourrat A, Legret P. Standardisation d'un extrait de propolis et identification des principaux constituants [Standardization of propolis extract and identification of principal constituents]. J Pharm Belg. 1994 Nov-Dec;49(6):462-8. French. PMID: 7884635.
  • 4. Zeytunluoglu, A., & Zihnioglu, F. (2015). Evaluation of some plants for potential dipeptidyl peptidase IV inhibitory effects in vitro. Turkish Journal of Biochemistry-Turk Biyokimya Dergisi, 40(3), 217–223. https://doi.org/10.1515/tjb.2015.0004
  • 5. T. Matsui, C. Yoshimoto, K. Osajima, T. Oki, Y. Osajima In vitro survey of α-glucosidase inhibitory food components Bioscience, Biotechnology and Biochemistry, 60 (1996), pp. 2019-2022
  • 6. Forbes, J. M., & Fotheringham, A. K. (2017). Vascular complications in diabetes: old messages, new thoughts. Diabetologia, 60(11), 2129-2138. https://doi.org/10.1007/s00125-017-4360-x
  • 7. Cho, N., Shaw, J. E., Karuranga, S., Huang, Y., da Rocha Fernandes, J. D., Ohlrogge, A. W., & Malanda, B. (2018). IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045. Diabetes research and clinical practice, 138, 271-281. https://doi.org/10.1016/j.diabres.2018.02.023
  • 8. Kajaria, D., Ranjana, J. T., Tripathi, Y. B., & Tiwari, S. (2013). In-vitro α amylase and glycosidase inhibitory effect of ethanolic extract of antiasthmatic drug—Shirishadi. Journal of advanced pharmaceutical technology & research, 4(4), 206.
  • 9. Wang, X., Cao, J., Dai, X., Xiao, J., Wu, Y., & Wang, Q. (2017). Total flavonoid concentrations of bryophytes from Tianmu Mountain, Zhejiang Province (China): Phylogeny and ecological factors. PloS one, 12(3), e0173003.
  • 10. ASLANBABA, B., YILMAZ, S., YAYINTAŞ, Ö. T., ÖZYURT, D., & ÖZTÜRK, B. D. (2017). Total phenol content and antioxidant activity of mosses from Yenice forest (Ida mountain). Journal of Scientific Perspectives, 1(1), 1-12.
  • 11. Sethi, S., Joshi, A., Arora, B., Bhowmik, A., Sharma, R. R., & Kumar, P. (2020). Significance of FRAP, DPPH, and CUPRAC assays for antioxidant activity determination in apple fruit extracts. European Food Research and Technology, 246(3), 591-598.
  • 12. McCue, P., Kwon, Y.I., Shetty, K., 2005, Anti-diabetic and anti-hypertensive potential of sprouted and solid-state bioprocessed soybean, Asia Pac J Clin Nutr., 14(2), 145-52.
  • 13. Rahim, F., Zaman, K., Taha, M., Ullah, H., Ghufran, M., Wadood, A., ... & Nawaz, F. (2020). Synthesis, in vitro alpha-glucosidase inhibitory potential of benzimidazole bearing bis-Schiff bases and their molecular docking study. Bioorganic chemistry, 94, 103394.
  • 14. Xiong, Y., Ng, K., Zhang, P., Warner, R. D., Shen, S., Tang, H. Y., ... & Fang, Z. (2020). In Vitro α-Glucosidase and α-Amylase Inhibitory Activities of Free and Bound Phenolic Extracts from the Bran and Kernel Fractions of Five Sorghum Grain Genotypes. Foods, 9(9), 1301.
  • 15. Peng, C.-H., Yang, Y.-S., Chan, K.-C., Wang, C.-J., Chen, M.-L., Huang, C.-N., et al. (2014). Hibiscus sabdariffa polyphenols alleviate insulin resistance and renal epithelial to mesenchymal transition: a novel action mechanism mediated by type 4 dipeptidyl peptidase. J. Agric. Food Chem. 62, 9736–9743. doi: 10.1021/ jf5024092
  • 16. Kalhotra P, Chittepu VCSR, Osorio-Revilla G, Gallardo-Velazquez T. Phytochemicals in Garlic Extract Inhibit Therapeutic Enzyme DPP-4 and Induce Skeletal Muscle Cell Proliferation: A Possible Mechanism of Action to Benefit the Treatment of Diabetes Mellitus. Biomolecules. 2020 Feb 14;10(2):305. doi: 10.3390/biom10020305. PMID: 32075130; PMCID: PMC7072494.
  • 17. Zakłos-Szyda, M., Kowalska-Baron, A., Pietrzyk, N., Drzazga, A., & Podsędek, A. (2020). Evaluation of Viburnum opulus L. Fruit Phenolics Cytoprotective Potential on Insulinoma MIN6 Cells Relevant for Diabetes Mellitus and Obesity. Antioxidants (Basel, Switzerland), 9(5), 433. https://doi.org/10.3390/antiox9050433
  • 18. Fan J, Johnson MH, Lila MA, Yousef G, de Mejia EG. Berry and Citrus Phenolic Compounds Inhibit Dipeptidyl Peptidase IV: Implications in Diabetes Management. Evid Based Complement Alternat Med. 2013;2013:479505. doi: 10.1155/2013/479505. Epub 2013 Aug 29. PMID: 24069048; PMCID: PMC3773436.
  • 19. Ansari, N. A., & Rasheed, Z. (2009). Non-enzymatic glycation of proteins: From diabetes to cancer. Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry, 3(4), 335–342. https://doi.org/10.1134/s1990 75080 9040027
  • 20. Sattarahmady, N., Moosavi-Movahedi, A. A., Ahmad, F., Hakimelahi, G. H., Habibi-Rezaei, M., Saboury, A. A., & Sheibani, N. (2007). Formation of the molten globule-like state during prolonged glycation of human serum albumin. Biochimica et Biophysica Acta (BBA)-General Subjects, 1770(6), 933-942.
  • 21. Christen, Y. (2000). Oxidative stress and Alzheimer disease. The American journal of clinical nutrition, 71(2), 621S-629S
  • 22. Decker, E. L., & Reski, R. (2020). Mosses in biotechnology. Current opinion in biotechnology, 61, 21-27.
  • 23. Li, X., Wang, X., Chen, D., & Chen, S. (2011). Antioxidant activity and mechanism of protocatechuic acid in vitro. Functional Foods in Health and Disease, 1(7), 232. https://doi.org/10.31989/ ffhd.v1i7.127
  • 24. Kani, H. K., Kocazorbaz, E. K., & Zihnioglu, F. (2019). Investigation and isolation of peptide based antiglycating agents from various sources. Turkish Journal of Biochemistry, 44(5), 699-705.
  • 25. Duez, H., Cariou, B., & Staels, B. (2012). DPP-4 inhibitors in the treatment of type 2 diabetes. Biochemical pharmacology, 83(7), 823-832.
  • 26. Dukic-Stefanovic, S., Schinzel, R., Riederer, P., & Münch, G. (2001). AGES in brain ageing: AGE-inhibitors as neuroprotective and anti-dementia drugs?. Biogerontology, 2(1), 19-34.
  • 27. Nawale, R. B., Mourya, V. K., & Bhise, S. B. (2006). Non-enzymatic glycation of proteins: a cause for complications in diabetes.
There are 27 citations in total.

Details

Primary Language English
Journal Section Research Articles
Authors

Ebru Kocadağ Kocazorbaz 0000-0001-5611-5235

Kerem Tok 0000-0002-7244-3949

Hichem Moulahoum 0000-0003-3934-6415

Rabia Nur Ün 0000-0001-7903-9167

Publication Date August 30, 2021
Submission Date January 26, 2021
Acceptance Date June 17, 2021
Published in Issue Year 2021

Cite

APA Kocadağ Kocazorbaz, E., Tok, K., Moulahoum, H., Ün, R. N. (2021). Phytochemical and Bioactivity Analysis of Several Methanolic Extracts of Nine Bryophytes Species. Sakarya University Journal of Science, 25(4), 938-949. https://doi.org/10.16984/saufenbilder.868944
AMA Kocadağ Kocazorbaz E, Tok K, Moulahoum H, Ün RN. Phytochemical and Bioactivity Analysis of Several Methanolic Extracts of Nine Bryophytes Species. SAUJS. August 2021;25(4):938-949. doi:10.16984/saufenbilder.868944
Chicago Kocadağ Kocazorbaz, Ebru, Kerem Tok, Hichem Moulahoum, and Rabia Nur Ün. “Phytochemical and Bioactivity Analysis of Several Methanolic Extracts of Nine Bryophytes Species”. Sakarya University Journal of Science 25, no. 4 (August 2021): 938-49. https://doi.org/10.16984/saufenbilder.868944.
EndNote Kocadağ Kocazorbaz E, Tok K, Moulahoum H, Ün RN (August 1, 2021) Phytochemical and Bioactivity Analysis of Several Methanolic Extracts of Nine Bryophytes Species. Sakarya University Journal of Science 25 4 938–949.
IEEE E. Kocadağ Kocazorbaz, K. Tok, H. Moulahoum, and R. N. Ün, “Phytochemical and Bioactivity Analysis of Several Methanolic Extracts of Nine Bryophytes Species”, SAUJS, vol. 25, no. 4, pp. 938–949, 2021, doi: 10.16984/saufenbilder.868944.
ISNAD Kocadağ Kocazorbaz, Ebru et al. “Phytochemical and Bioactivity Analysis of Several Methanolic Extracts of Nine Bryophytes Species”. Sakarya University Journal of Science 25/4 (August 2021), 938-949. https://doi.org/10.16984/saufenbilder.868944.
JAMA Kocadağ Kocazorbaz E, Tok K, Moulahoum H, Ün RN. Phytochemical and Bioactivity Analysis of Several Methanolic Extracts of Nine Bryophytes Species. SAUJS. 2021;25:938–949.
MLA Kocadağ Kocazorbaz, Ebru et al. “Phytochemical and Bioactivity Analysis of Several Methanolic Extracts of Nine Bryophytes Species”. Sakarya University Journal of Science, vol. 25, no. 4, 2021, pp. 938-49, doi:10.16984/saufenbilder.868944.
Vancouver Kocadağ Kocazorbaz E, Tok K, Moulahoum H, Ün RN. Phytochemical and Bioactivity Analysis of Several Methanolic Extracts of Nine Bryophytes Species. SAUJS. 2021;25(4):938-49.

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