Investigating the Effect of Sympathetic Skin Response Parameters on the Psychological Test Scores in Patients with Fibromyalgia Syndrome by Using ANNS

Year 2013, Volume: 17 Issue: 1, 27 - 32, 01.04.2013

Murat Yıldız Özhan Özkan Etem Köklükaya

Abstract

In this study, psychological tests such as Visual Analogue Pain Scale, Verbal Pain Scale, Beck Depression Inventory, Beck Anxiety Inventory, Hamilton Depression Rating Scale and Hamilton Anxiety Scale were applied to the selected healthy subjects and patients with Fibromyalgia Syndrome (FMS) in Suleyman Demirel University, Faculty of Medicine, Department of Physical Medicine and Rehabilitation and the scores were recorded. A measurement system was established in the same department of the university to measure the sympathetic skin response (SSR) from the subjects. The SSR was measured and recorded. The parameters such as latency time, maximum amplitude and the elapsed time were calculated by using Matlab software from the recorded SSR data. SSR parameters were added to the scores and diagnosis accuracy percentages of the FMS calculated by using artificial neural networks. Obtained results from the simulations showed that the specified parameters of the SSR and FMS were concerned and these parameters can be used as a diagnostic method in FMS.

Keywords

Sympathetic skin response, fibromyalgia syndrome, ANN, psychological tests in fibromyalgia

Fibromiyalji Hastalarında Sempatik Deri Cevabının Psikolojik Test Skorlarına Etkisinin YSA Kullanılarak İncelenmesi

Abstract

In this study, psychological tests such as Visual Analogue Pain Scale, Verbal Pain Scale, Beck Depression Inventory, Beck Anxiety Inventory, Hamilton Depression Rating Scale and Hamilton Anxiety Scale were applied to the selected healthy subjects and patients with Fibromyalgia Syndrome (FMS) in Suleyman Demirel University, Faculty of Medicine, Department of Physical Medicine and Rehabilitation and the scores were recorded. A measurement system was established in the same department of the university to measure the sympathetic skin response (SSR) from the subjects. The SSR was measured and recorded. The parameters such as latency time, maximum amplitude and the elapsed time were calculated by using Matlab software from the recorded SSR data. SSR parameters were added to the scores and diagnosis accuracy percentages of the FMS calculated by using artificial neural networks (ANNs). Obtained results from the simulations showed that the specified parameters of the SSR and FMS were concerned and these parameters can be used as a diagnostic method in FMS.

Keywords

Sempatik deri cevabı, fibromiyalji sendromu, YSA, fibromiyaljide psikolojik testler

References

• Krypel L.L., “Fibromyalgia: A Review of Its Pathophysiology and Drug Treatment”, Journal of Pharmacy Practice, 22(1):6–16, Feb 2009.
• Eisinger J., “Dysautonomia, fibromyalgia and reflex dystrophy”, Arthritis Research & Therapy, 9(4):105, 200 Fietta P., Fietta P., Manganelli P., “Fibromyalgia and psychiatric disorders”, Acta Biomed., 78(2):88-95, Aug. 200 Martinez-Lavin, M., “Biology and therapy of fibromyalgia. Stress, the stress response system, and fibromyalgia”, Arthritis Research & Therapy, 9(4):216, 200 Toyukara, M., “Sympathetic skin responses: the influence of electrical stimulus intensity and habituation on the waveform”, Clinical Autonomic Research, 16(2):130-135, 2006.
• Özkan Ö., Yildiz M., Köklükaya E., “The Correlation Of Laboratory Tests And Sympathetic Skin Response Parameters By Using Artificial Neural Networks In Fibromyalgia Patients”, Journal of Medical Systems, 36(3):1841-1848, June 2012.
• Ahuja N.D., Agarwal A.K., Mahajan N.M., Mehta N.H., Kapadia H.N., “GSR and HRV:Its Application in Clinical Diagnosis”, Computer-Based Medical Systems, 2003, Proceedings, 16th IEEE Symposium, 279-283, India, 26-27 June 2003,.
• Martinez-Lavin, M., Vargas, A., “Complex adaptive systems allostasis in fibromyalgia”, Rheumatic Disease Clinics of North America, 35(2):285-298, July 2009.
• Özkan, Ö., Yildiz, M., Bilgin, S., Köklükaya, E., “Measuring the Sympathetic Skin Response on Body and Using as Diagnosis-Purposed for Lung Cancer Patients by Artificial Neural Networks”, Journal of Medical Systems, 34(3):407-412, June 2010.
• Özkan, Ö., Yıldız, M., Köklükaya, E., “Fibromiyalji sendromunun teşhisinde kullanılan laboratuar testlerinin sempatik deri cevabı parametreleriyle desteklenerek teşhis doğruluğunun arttırılması", Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 15(1): 1-7, Haziran 20 Ries, A.L., Bauldoff, G.S., Carlin, B.W., Casaburi, R., Emery, C.F., Mahler, D.A., Make, B., Rochester, C.L., Zuwallack, R., Herrerias, C., “Pulmonary rehabilitation: Joint ACCP/AACVPR evidence based guidelines”, Chest., 131(5):4-42, May 2007.
• Perez-Higueras, A., Alvarez, L., Rossi, R., Quinones, D., Al-Assir, I., “Percutaneous vertebroplasty: Long term clinical and radiological outcome”, Interventional Neuroradiology, 44(11):950-954, 2002.
• Çakır, T., Evcik, D., Dündar, Ü., Yiğit, İ., Kavuncu, V., “Evaluation of sympathetic skin response and F-wave in fibromyalgia syndrome patients”, Turkish Journal of Rheumatology, 26(1):38-43, 2011.
• Ulusoy M., Şahin N.H., Erkmen H., “Turkish version of the Beck Anxiety Inventory: Psychometric properties”, Journal of Cognitive Psychotherapy, 12(2):163-172, 1998
• Shear, M.K., Bilt, J.V., Rucci, P., Endicott, J., Lydiard, B., Otto, M.W., Pollack, M.H., Chandler, L., Williams, J., Ali, A., Frank, D.M., “Reliability and validity of a structured interview guide for the Hamilton Anxiety Rating Scale (SIGH-A)”, Depression and Anxiety, 13(4):166-178, 2001.
• Aben, I., Verhey, F., Lousberg, R., Lodder, J., Honig, A., “Validity of the Beck depression inventory, hospital anxiety and depression scale, SCL-90, and Hamilton depression rating scale as screening instruments for depression in stroke patients”, Psychosomatics, 43(5):386-393, 2002.
• Wolfe, F., Smythe, H.A., Yunus, M.B., “The American College of Rheumatology 1990 criteria for the classification of fibromyalgia”, Report of the Multicenter Criteria Committee., Arthritis Rheumatology, 33(2):160172, Feb. 1990.
• Chroni, E., Argyriou, A.A., Polychronopoulos, P., Sirrou, V., “The effect of stimulation technique on sympathetic skin responses in healthy subjects”, Clinical Autonomic Research, 16(6):96-400, 2006.
• Öztemel, E. , “Yapay Sinir Ağları”, Papatya Yayıncılık, 2003.