Investigation on Photon Interaction Properties of Some Polymers Used in Production of Hydrogels

Year 2018, , 97 - 107, 30.11.2018

Esra Kavaz

https://doi.org/10.29233/sdufeffd.453522

Cited By: 1

Abstract

Due to their excellent features and applications, hydrogels become so popular and are
used for fabricating contact lenses, cancer treatment, hygiene products, tissue engineering, drug
and delivery systems. Simultaneously use of hydrogels with radiotherapy is known to be effective
in protecting the healthy cells from high radiation. From this point on, it is necessary to know
radiation attenuation properties of compounds used in production of hydrogel. In the present
study, half value layer (HVL), effective atomic number (Zeff), effective electron density (Nel) and
energy absorption and exposure buildup factors (EABF and EBF) of eight hydrogel samples
(hyaluronic acid, chitosan, fibrin, dextran sulfate, pectin, alginic acid, chondroitin sulfate and
carrageenan) have been investigated. From the obtained results, it might be concluded that these
parameters depend on the elemental composition of the samples. It is seen that dextran sulfate has
most superior radiation absorption capacity while fibrin has the lowest when compared to other
samples.

Keywords

Hydrogel, Radiation, HVL, Effective atomic number, Buildup factor

Hidrojel Üretiminde Kullanılan Bazı Polimerlerin Foton Etkileşim Özelliklerinin İncelenmesi

Abstract

Mükemmel özellikleri ve uygulamaları nedeniyle, hidrojeller son derece popülerdir ve
kontakt lenslerin üretimi, kanser tedavisi, hijyen ürünleri, doku mühendisliği ve ilaç verme
sistemleri için kullanılır. Hidrojellerin radyoterapi ile eş zamanlı kullanımının, sağlıklı hücrelerin
yüksek radyasyondan korunmasında etkili olduğu bilinmektedir. Bu noktadan hareketle, hidrojel
üretiminde kullanılan bileşikerin radyasyon azaltma özelliklerini bilmek gereklidir. Bu çalışmada,
sekiz hidrojel örneğinin (aljinik asit, hiyalüronik asit, kitosan, fibrin, carrageenan, pektin,
kondroitin sülfat ve dekstran sülfat ) yarı değer kalınlığı (HVL), etkin atom numarası (Zeff), etkin
elektron yoğunluğu (Nel) ve enerji absorpsiyon ve maruz kalma kuvvetlendirme faktörleri (EABF
ve EBF) incelendi. Elde edilen sonuçlara göre, bu parametreler, numunelerin elementel
kompozisyonuna bağlı olup, diğer örnekler ile kıyaslandığında dekstran sülfatın daha üstün
radyasyon soğurma kapasitesine sahipken fibrinin en az olduğu görülebilir. 

Keywords

HVL, Hidrojel, Radyasyon, Etkin atom numarası, Kuvvetlendirme faktörü

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