Nükleer Tıpta Kullanılan Bazı Radyofarmasötiklerin Üretim Reaksiyon Tesir Kesitlerinin Yoğunluğa Bağlı Yeni Parametrelerle Hesaplanması
Abstract
Nükleer tıpta, radyofarmasötikler
tanı veya tedavi amacıyla kullanılmaktadır. Yapılarında radyonüklid içeren
radyofarmasötikler, reaktör, jeneratör veya siklotronlarla üretilirler ve genellikle
sintigrafik veya tomografik incelemelerde kullanılır. Üretilen radyonüklidler,
organik veya inorganik maddelerle birlikte vücuda verilebilir. Bu çalışmada, (n,
α) reaksiyonları için Tel ve arkadaşları (2008) tarafından geliştirilen
yarı-ampirik tesir kesit formülü kullanılarak seçilen iki radyofarmasötik
çekirdek (99Tc ve 115In) için üretim reaksiyonu tesir
kesitleri hesaplanmıştır. Ayrıca, yoğunluğa bağlı ampirik (n, α) (2008) nükleer
reaksiyon tesir kesitleri dört Skyrme Hartree Fock parametreleri (S3, T3, SKM
ve SKM*) kullanılarak da incelenmiştir. Tel
ve ark. (2008) tarafından geliştirilen yarı ampirik formülünden hesaplanan
değer uyumlu çıkarken, yoğunluğa bağlı hesaplamaların deneysel değerlerden daha
aşağıda olduğu gözlemlenmiştir.
References
- D. L. Bailey, J.L. Humm, A. Todd-Pokropek and A. V. Aswegen, “Nuclear medicine physics, a handbook for students and teachers” in Basic Physics For Nuclear Medicine, International atomic energy agency, Vienna, 2014, pp. 1-48.
- E. Tel, Ş. Okuducu, M.H. Bölükdemir and G. Tanir, “Semi-empirical systematics of (n, 2n), (n, ?) reactions cross sections at 14–15 MeV neutron energy”, Int. J. Mod. Phys. E, vol. 17, pp. 567-583, 2008.
- R. Baldık, “Investigation of the ground state features of some exotic nuclei using effective Skyrme interaction”, Ph.D. thesis, Zonguldak Karaelmas University, Science institute, 2010.
- E. Tel, Y. Kavun, M. Sahan and A. Aydin, “A Study on the New Empirical Cross Section Formulae for (?, p) Reactions at 20?±?1 MeV Incident Energy”, J. Fusion Energ, vol.37, pp. 270–274, 2018.
- M. E. Korkmaz, M. Yiğit and O. Agar, “Investigation of reaction cross sections of 10,11B with protons and neutrons of 0 – 30 MeV incoming energy using nuclear models” Balkan Physics Letters, vol. 20, pp. 293 – 300, 2012.
- N. N. Bogolyubov, “On a variational principle in the many-body problem,” Soviet Physics Doklady, vol. 3, pp. 292-294, 1958.
- M. Beiner, H. Flocard, N. Van Giai and P. Quentin, “Nuclear ground-state properties and self-consistent calculations with the Skyrme interaction: (I). Spherical description”, Nucl. Phys. A, vol. 238, pp. 29-69, 1975.
- A.Yu. Konobeyev, C.H.M. Broeders, U. Fischer, L. Mercatali, I. Schmuck, and S.P. Simakov, “The Proton Activation Data File PADF-2007”, International Conference on Nuclear Data for Science and Technology, 2007.
- D. Vauthering and D. M. Brink, “Hartree-Fock Calculations with Skyrme's Interaction. I. Spherical Nuclei”, Phys. Rev. C, vol. 5, pp. 626-647, 1972.
- A. Aydin, E. Tel and M. Sahan, “Calculation of equilibrium and pre-equilibrium 4He emission spectra at 62 MeV proton incident energy”, J. Fusion Energ, vol. 30, pp.34–38, 2011.
- L. G. Qiang, “A systematic study of nuclear properties with Skyrme forces” J. Phys. G: Nucl. Part. Phys., vol. 17, pp. 1-34, 1991.
- T. H. R. Skyrme, “The effective nuclear potential”, Nucl. Phys., vol. 9, pp. 615-634, 1959.
- P. Reimer, A. J. Koning, A. J. M. Plompen, S. M. Qaim and S. Sudár, “Neutron induced reaction cross sections for the radioactive target nucleus Tc-99”, Nucl. Phys. A, vol.815,pp. 1-17, 2000.
- V. N. Levkovskii, “Relative cross sections of the (n,p) and (n,a) reactions on elements with several stable isotopes”, J. Exptl. Theoret. Phys., vol.33, pp.1520-1521, 1957.
Calculation of Production Reaction Cross Section of Some Radiopharmaceuticals Used in Nuclear Medicine by New Density Dependent Parameters
Abstract
In
nuclear medicine, radiopharmaceuticals are used for diagnosis or treatment
purposes. Radiopharmaceuticals containing radionuclide in their structure are
produced by reactors, generators or cyclotrons and are generally used for scintigraphy
or tomographic investigations. The produced radionuclides can be given to the
human body together with organic or inorganic substances. In this study,
the production reaction cross sections were calculated for two selected
radiopharmaceutical nuclei (99Tc and 115In) using the semi-empirical cross section formula for the (n, α) reactions developed by Tel et al. (2008).
The density depending on (n, α) reaction cross sections were also investigated with
the four Skyrme Hartree Fock parameters (S3, T3, SKM and SKM*). While the calculated
value from the semi-empirical formula
developed by Tel et al. (2008) gave reasonable results, the density-dependent
calculations were observed lower values than that of experimental values.
References
- D. L. Bailey, J.L. Humm, A. Todd-Pokropek and A. V. Aswegen, “Nuclear medicine physics, a handbook for students and teachers” in Basic Physics For Nuclear Medicine, International atomic energy agency, Vienna, 2014, pp. 1-48.
- E. Tel, Ş. Okuducu, M.H. Bölükdemir and G. Tanir, “Semi-empirical systematics of (n, 2n), (n, ?) reactions cross sections at 14–15 MeV neutron energy”, Int. J. Mod. Phys. E, vol. 17, pp. 567-583, 2008.
- R. Baldık, “Investigation of the ground state features of some exotic nuclei using effective Skyrme interaction”, Ph.D. thesis, Zonguldak Karaelmas University, Science institute, 2010.
- E. Tel, Y. Kavun, M. Sahan and A. Aydin, “A Study on the New Empirical Cross Section Formulae for (?, p) Reactions at 20?±?1 MeV Incident Energy”, J. Fusion Energ, vol.37, pp. 270–274, 2018.
- M. E. Korkmaz, M. Yiğit and O. Agar, “Investigation of reaction cross sections of 10,11B with protons and neutrons of 0 – 30 MeV incoming energy using nuclear models” Balkan Physics Letters, vol. 20, pp. 293 – 300, 2012.
- N. N. Bogolyubov, “On a variational principle in the many-body problem,” Soviet Physics Doklady, vol. 3, pp. 292-294, 1958.
- M. Beiner, H. Flocard, N. Van Giai and P. Quentin, “Nuclear ground-state properties and self-consistent calculations with the Skyrme interaction: (I). Spherical description”, Nucl. Phys. A, vol. 238, pp. 29-69, 1975.
- A.Yu. Konobeyev, C.H.M. Broeders, U. Fischer, L. Mercatali, I. Schmuck, and S.P. Simakov, “The Proton Activation Data File PADF-2007”, International Conference on Nuclear Data for Science and Technology, 2007.
- D. Vauthering and D. M. Brink, “Hartree-Fock Calculations with Skyrme's Interaction. I. Spherical Nuclei”, Phys. Rev. C, vol. 5, pp. 626-647, 1972.
- A. Aydin, E. Tel and M. Sahan, “Calculation of equilibrium and pre-equilibrium 4He emission spectra at 62 MeV proton incident energy”, J. Fusion Energ, vol. 30, pp.34–38, 2011.
- L. G. Qiang, “A systematic study of nuclear properties with Skyrme forces” J. Phys. G: Nucl. Part. Phys., vol. 17, pp. 1-34, 1991.
- T. H. R. Skyrme, “The effective nuclear potential”, Nucl. Phys., vol. 9, pp. 615-634, 1959.
- P. Reimer, A. J. Koning, A. J. M. Plompen, S. M. Qaim and S. Sudár, “Neutron induced reaction cross sections for the radioactive target nucleus Tc-99”, Nucl. Phys. A, vol.815,pp. 1-17, 2000.
- V. N. Levkovskii, “Relative cross sections of the (n,p) and (n,a) reactions on elements with several stable isotopes”, J. Exptl. Theoret. Phys., vol.33, pp.1520-1521, 1957.
Details
| Primary Language | English |
|---|---|
| Subjects | Metrology, Applied and Industrial Physics |
| Journal Section | Makaleler |
| Authors | |
| Publication Date | May 31, 2019 |
| Published in Issue | Year 2019 |