Nükleer Tıpta Kullanılan Bazı Radyofarmasötiklerin Üretim Reaksiyon Tesir Kesitlerinin Yoğunluğa Bağlı Yeni Parametrelerle Hesaplanması

Abstract

Nükleer tıpta, radyofarmasötikler tanı veya tedavi amacıyla kullanılmaktadır. Yapılarında radyonüklid içeren radyofarmasötikler, reaktör, jeneratör veya siklotronlarla üretilirler ve genellikle sintigrafik veya tomografik incelemelerde kullanılır. Üretilen radyonüklidler, organik veya inorganik maddelerle birlikte vücuda verilebilir. Bu çalışmada, (n, α) reaksiyonları için Tel ve arkadaşları (2008) tarafından geliştirilen yarı-ampirik tesir kesit formülü kullanılarak seçilen iki radyofarmasötik çekirdek (⁹⁹Tc ve ¹¹⁵In) için üretim reaksiyonu tesir kesitleri hesaplanmıştır. Ayrıca, yoğunluğa bağlı ampirik (n, α) (2008) nükleer reaksiyon tesir kesitleri dört Skyrme Hartree Fock parametreleri (S3, T3, SKM ve SKM*)  kullanılarak da incelenmiştir. Tel ve ark. (2008) tarafından geliştirilen yarı ampirik formülünden hesaplanan değer uyumlu çıkarken, yoğunluğa bağlı hesaplamaların deneysel değerlerden daha aşağıda olduğu gözlemlenmiştir.

Keywords

• Nükleer tıp,Nükleer reaksiyonlar,Tesir kesiti,Skyrme potansiyeli,Asimetri parametresi

Calculation of Production Reaction Cross Section of Some Radiopharmaceuticals Used in Nuclear Medicine by New Density Dependent Parameters

Abstract

In nuclear medicine, radiopharmaceuticals are used for diagnosis or treatment purposes. Radiopharmaceuticals containing radionuclide in their structure are produced by reactors, generators or cyclotrons and are generally used for scintigraphy or tomographic investigations. The produced radionuclides can be given to the human body together with organic or inorganic substances.  In this study,  the production reaction cross sections were calculated for two selected radiopharmaceutical nuclei (⁹⁹Tc and ¹¹⁵In) using the semi-empirical cross section formula for the (n, α) reactions developed by Tel et al. (2008). The density depending on (n, α) reaction cross sections were also investigated with the four Skyrme Hartree Fock parameters (S3, T3, SKM and SKM*). While the calculated value from the semi-empirical formula developed by Tel et al. (2008) gave reasonable results, the density-dependent calculations were observed lower values than that of experimental values. 

Keywords

• Nuclear medicine,Nuclear reactions,Cross section,Skyrme potential,Asymmetry parameters

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