Oksim Grubu İçeren Dinükleer Fe(II) ve Mn(II) Komplekslerinin Sentezi, Karakterizasyonu, Katalaz ve Katekolaz Enzim Aktivitelerinin İncelenmesi

Year 2014, Volume: 9 Issue: 1, 163 - 175, 15.07.2014

Bülent Dede , Hanife Korkmaz

Abstract

In this study, dinuclear iron(II) and manganese(II) complexes were synthesized using two different ligands containing oxime group. These new complexes have been characterized by elemental analyses, ICP-OES, FT-IR spectra, TG, magnetic susceptibility and conductivity measurements. The results suggest that the dinuclear complexes of H2L1 and H4L2 have a metal:ligand ratio of 2:2 and 2:1, respectively. Furthermore complexes were each tested both for their ability to catalyse the disproportionation of hydrogen peroxide in the presence of the added base imidazole and oxidation reaction of 3,5-di-tert-butylcatechol to the 3,5-di-tert-butylquinone presence of O2. It was found that all complexes exhibited good both catalase and catecholase activity

Keywords

oxime, complex, catalase, catecholase, enzyme

Oksim Grubu İçeren Dinükleer Fe(II) ve Mn(II) Komplekslerinin Sentezi, Karakterizasyonu, Katalaz ve Katekolaz Enzim Aktivitelerinin İncelenmesi

Abstract

Bu çalışmada, oksim grubu içeren iki farklı ligand kullanılarak dinükleer demir(II) ve mangan(II) kompleksleri sentezlenmiştir. Bu yeni kompleksler elemental analiz, ICP-OES, FT-IR spektroskopisi, TG, manyetik duyarlılık ve iletkenlik ölçümleriyle karakterize edilmiştir. Sonuçlar H2L1 ve H4L2'nin dinükleer komplekslerinin sırasıyla 2:2 ve 2:1 metal:ligand oranına sahip olduklarını göstermektedir. Ayrıca her bir kompleksin imidazol varlığında hidrojen peroksitin disproporsiyonu reaksiyonundaki ve O2 varlığında 3,5-di-t-bütilkatekolün 3,5-di-t-bütilkinona yükseltgenmesi reaksiyonundaki katalitik etkinliği incelenmiştir. Tüm komplekslerin iyi katalaz ve katekolaz aktiviteye sahip oldukları bulunmuştur.
Anahtar Kelimeler: oksim, kompleks, katalaz, katekolaz, enzim

Keywords

oksim, kompleks, katalaz, katekolaz, enzim

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