New Morpholinoethyl-Substituted (NHC)PdBr2(3-Chloropyridine) Complexes: Synthesis, Characterization and Catalytic Activity in the Suzuki-Miyaura Reaction

Year 2019, , 374 - 380, 25.08.2019

Aydın Aktaş

https://doi.org/10.19113/sdufenbed.476479

Abstract

Recently,
chemists studying with organometallic compounds are increasingly interested in
Pd-PEPPSI complexes. This study contains the synthesis of the
2-morpholinoethyl-substituted Pd-PEPPSI complexes and their catalytic activity
in the Suzuki-Miyaura reaction. Synthesized the Pd-PEPPSI complexes have been
prepared from the 2-morpholinoethyl-substituted N-heterocyclic carbene (NHC)
precursors, palladium chloride and 3-chloropyridine. These complexes have been
characterized by using ¹H NMR, ¹³C NMR, FTIR spectroscopy
and elementel analysis techniques. Also, synthesized the Pd-PEPPSI complexes
have been examined as catalysts in the Suzuki-Miyaura cross-coupling reaction
with arylboronic acid derivatives and have shown to exhibit well activity in
this reaction.

Keywords

Phenylboronic acid, N-Heterocyclic carbenes, PEPPSI complexes, Suzuki-Miyaura reaction

Yeni Morfolinoetil-Sübstitüyeli (NHC)PdBr2(3-Kloropiridin) Kompleksleri: Sentez, Karakterizasyon ve Suzuki-Miyaura Reaksiyonundaki Katalitik Aktivite

Abstract

Son
yıllarda, organometalik bileşiklerle çalışan kimyagerler, Pd-PEPPSI
komplekslerine daha fazla ilgi duymaktadırlar. Bu çalışma; 2-morfolinoetil
sübs-titüyeli Pd-PEPPSI komplekslerinin sentezini ve bunların Suzuki-Miyaura
çapraz-eşleşme reaksiyonundaki katalitik aktivitelerini içerir. Sentezlenen
Pd-PEPPSI kompleksleri; 2-morfolinoetil sübstitüyeli N-heterosiklik karben
(NHC) öncüleri, paladyum klorür ve 3-kloropiridin'den hazırlanmıştır. Bu
kompleksler, ¹H NMR, ¹³C NMR, FTIR spektroskopisi ve
elementel analiz teknikleri kullanılarak karakterize edilmiştir. Ayrıca,
sentezlenen Pd-PEPPSI kompleksleri, Suzuki-Miyaura çapraz-eşleşme
reaksiyonunda katalizör olarak incelenmiş ve bu reaksiyonda iyi aktivite
sergiledikleri gözlenmiştir.

Keywords

Fenilboronik asit, N-Heterosiklik karbenler, PEPPSI kompleksleri, Suzuki-Miyaura reaksiyonu

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