New Morpholinoethyl-Substituted (NHC)PdBr2(3-Chloropyridine) Complexes: Synthesis, Characterization and Catalytic Activity in the Suzuki-Miyaura Reaction

Abstract

Recently, chemists studying with organometallic compounds are increasingly interested in Pd-PEPPSI complexes. This study contains the synthesis of the 2-morpholinoethyl-substituted Pd-PEPPSI complexes and their catalytic activity in the Suzuki-Miyaura reaction. Synthesized the Pd-PEPPSI complexes have been prepared from the 2-morpholinoethyl-substituted N-heterocyclic carbene (NHC) precursors, palladium chloride and 3-chloropyridine. These complexes have been characterized by using ¹H NMR, ¹³C NMR, FTIR spectroscopy and elementel analysis techniques. Also, synthesized the Pd-PEPPSI complexes have been examined as catalysts in the Suzuki-Miyaura cross-coupling reaction with arylboronic acid derivatives and have shown to exhibit well activity in this reaction.

Keywords

• Phenylboronic acid,N-Heterocyclic carbenes,PEPPSI complexes,Suzuki-Miyaura reaction

Yeni Morfolinoetil-Sübstitüyeli (NHC)PdBr2(3-Kloropiridin) Kompleksleri: Sentez, Karakterizasyon ve Suzuki-Miyaura Reaksiyonundaki Katalitik Aktivite

Abstract

Son yıllarda, organometalik bileşiklerle çalışan kimyagerler, Pd-PEPPSI komplekslerine daha fazla ilgi duymaktadırlar. Bu çalışma; 2-morfolinoetil sübs-titüyeli Pd-PEPPSI komplekslerinin sentezini ve bunların Suzuki-Miyaura çapraz-eşleşme reaksiyonundaki katalitik aktivitelerini içerir. Sentezlenen Pd-PEPPSI kompleksleri; 2-morfolinoetil sübstitüyeli N-heterosiklik karben (NHC) öncüleri, paladyum klorür ve 3-kloropiridin'den hazırlanmıştır. Bu kompleksler, ¹H NMR, ¹³C NMR, FTIR spektroskopisi ve elementel analiz teknikleri kullanılarak karakterize edilmiştir. Ayrıca, sentezlenen Pd-PEPPSI kompleksleri, Suzuki-Miyaura çapraz-eşleşme reaksiyonunda katalizör olarak incelenmiş ve bu reaksiyonda iyi aktivite sergiledikleri gözlenmiştir.

Keywords

• Fenilboronik asit,N-Heterosiklik karbenler,PEPPSI kompleksleri,Suzuki-Miyaura reaksiyonu

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