Bazı Yeni İsatin Türevlerinin Sentezi ve Yapılarının Aydınlatılması

Year 2019, Volume: 23 Issue: Special [en], 67 - 70, 01.03.2019

İnci Selin Doğan , Gökçe Gül Bölek Bahittin Kahveci

https://doi.org/10.19113/sdufenbed.432261

Cited By: 1

Abstract

Heterosiklik
halka sistemlerinde önemli bir rolü olan indol, önemli biyolojik etkiler
göstermektedir. Isatin (1H-indol-2,3-dion),
biyolojik özellikleri nedeniyle çok sayıda sentezde bir reaktif olarak
kullanılmıştır. Ayrıca, isatin, indol ve kinolin türevlerinin eldesinde ve
reaksiyonlarında kullanılan, bir heterosiklik halka sistemidir.  Bu çalışmada, iki yeni Schiff bazı
bileşikleri, 2-aminoantrasen ile isatin/5-nitro-isatinin reaksiyonuyla
sentezlendi. Sentezlenen bileşiklerin yapısı, IR, ¹H-NMR, ¹³C-NMR
spektrumları ve Kütle analizi kullanılarak spektroskopik yöntemlerle
aydınlatıldı.

Keywords

İsatin, İndol, Schiff bazı, Heterosiklik kimya, Sentez

Synthesis of Some New Isatin Derivatives and Identification of Their Structures

Abstract

Indole,
which has an important role in heterocyclic ring systems, exhibits significant
biological effects. Isatin (1H-indole-2,3-dione)
has been used as a reagent in a large number of synthesis due to its biological
properties. In addition, it is a heterocyclic ring system used for obtaining and
other reactions of indole and quinoline derivatives. In this study, two new
Schiff base compounds were synthesized by the reaction of 2-aminoantracene with
an isatin/5-nitro-isatin. The structure of the synthesized compounds, were
elucidated by spectroscopic methods using IR, ¹H-NMR, ¹³C-NMR
spectra and Mass analysis.

Keywords

Indole, Isatin, Schiff base, heterocyclic chemistry, Synthesis

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