Periodontal Health Status of Adolescents with Hashimoto Thyroiditis

Abstract

Objective: Possible mechanisms regarding the relationship between Hashimoto’ thyroiditis (HT) and periodontal disease were suggested to be the autoimmune mechanisms. The aim is to report the oral and periodontal health status of a sample of adolescents with HT; and to evaluate the factors affecting the oral and periodontal health of the adolescents with HT. Material- Method: Sixty adolescent girls aged between 12-18 years (mean±SD: 15.03±2.05 years) have participated. The study population was comprised of HT (n = 30) and control (C, n = 30) groups. In addition to the endocrinologic evaluations (metabolic parameters) and intra- and extra-oral examinations, periodontal examination including the recording of percentage of bleeding on probing (BOP %), gingival index (GI), plaque index (PI), and pocket depth (PD) was made. Results: Except the significantly higher anti-thyroid peroxidase (Anti-TPO) values in HT group than the C group (P = 0.001), none of the metabolic parameters have shown significant differences (P > 0.05). All of the subjects had gingivitis. The periodontal parameters were found not significantly different (P > 0.05). Salivary flow rate (SFR) has negative significant correlation with Anti-TPO (r = -0.367, P = 0.046), and cortisol has negative significant correlation with pocket depth (PD) (r = -0.378, P = 0.040). Conclusions: Significant correlations between gingival index (GI) and fT4, and PD and fT4 have led us to consider that the periodontal inflammation might relate to HT. The adolescence period should also kept in mind; which results in exaggerated host response to the dental plaque, and projected with the presence of gingivitis in the whole study population.

Keywords

• Hashimoto thyroiditis
• gingivitis
• salivary flow rate
• children
• autoimmune thyroiditis

Hashimoto Tiroiditi Olan Adölesanlarda Periodontal Sağlık Durumu

Abstract

Amaç: Hashimoto tiroiditi (HT) ile periodontal hastalık arasındaki ilişkiye ilişkin olası mekanizmaların otoimmün mekanizmalar olduğu öne sürülmüştür. Amaç, HT' li bir adölesan örnekleminin ağız ve diş sağlığı durumunu bildirmek; ve HT'li olan ve olmayan adölesanların klinik periodontal ve metabolik parametreleri arasındaki korelasyonları incelemektir.
Materyal-metot: Çalışma popülasyonunu 12-18 yaş arası (ortalama±SS: 15.03±2.05 yıl) HT (n = 30) ve kontrol (C, n = 30) gruplarından oluşan toplam 60 kız adölesan oluşturdu. Metabolik parametrelerin incelendiği endokrinolojik incelemelerin yanı sıra hastaların ağız dışı ve periodontal muayeneyi içeren (sondlamada kanama yüzdesi (SK%), gingival indeks (GI), plak indeksi (Pİ) ve cep derinliği (CD)) ağız içi muayeneleri de yapılarak kaydedildi.
Bulgular: HT grubunda C grubuna göre anlamlı olarak daha yüksek anti-tiroid peroksidaz (Anti-TPO) değerleri (P = 0.001) dışında, metabolik parametrelerin hiçbiri anlamlı farklılık göstermedi (P > 0,05). Deneklerin tamamında gingivitis vardı. Periodontal parametreler istatistiksel açıdan anlamlı farklı bulunmadı (P > 0,05). Tükürük akış hızı (SFR) Anti-TPO ile negatif anlamlı (r = -0.367, P = 0,046) ve kortizol düzeyi cep derinliği (CD) ile negatif anlamlı korelasyona sahipti (r = -0.378, P = 0,040).
Sonuç: Gingival indeks (GI) ve fT4 ile PD ve fT4 arasındaki önemli korelasyonlar, periodontal inflamasyonun HT ile ilişkili olabileceğini düşünmemize yol açmıştır. Çalışma popülasyonunun tamamında görülen gingivitis varlığının ergenlik döneminde dental plağa karşı oluşan aşırı konak yanıtı ile ilgili olabileceği de akılda tutulmalıdır.

Keywords

• Hashimoto tiroiditi
• diş eti iltihabı
• tükürük akış hızı
• çocuk
• otoimmün tiroidit

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