Effect of Gestational Diabetes Mellitus on Corneal Biomechanical Characteristics
Abstract
Objective: This study aimed to investigate whether gestational diabetes mellitus (GDM) affects the corneal biomechanical parameters.
Material-Method: Thirty-eight pregnant women, newly diagnosed with GDM and, age- and gestational age-matched 34 healthy pregnant females were enrolled in the study. The right eye of the participants was examined. The corneal parameters including corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated intraocular pressure (IOPg), and the corneal compensated IOP (IOPcc), obtained by The Ocular Response Analyzer (ORA) device were compared statistically.
Results: The mean and gestational age of the participants was 30.71 ±5.09 years, 25.95 ±1.56 weeks and 29.97 ±4.10 years, 25.76 ±1.30 weeks in pregnant females with GDM and healthy pregnant females, respectively. No significant differences in age (p=0.502) or gestational age (p=0.594) were noted. The values of CH, CRF, IOPg, and IOPcc were determined to be higher in pregnant females with GDM as compared to that in healthy pregnant females. However, there was no statistically significant difference in any other parameter (p=0.183, p=0.303, p=0.732 and p=0.330, respectively).
Conclusions: Short-term hyperglycemia does not affect the corneal biomechanical parameters.
Keywords
References
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Details
Primary Language
English
Subjects
Health Care Administration
Journal Section
Research Article
Publication Date
March 3, 2020
Submission Date
August 27, 2019
Acceptance Date
December 24, 2019
Published in Issue
Year 2020 Volume: 11 Number: 1