Soğuk Stres Uygulanan Ratlarda Nar Çiçeğinin (Punica Granatum) Plazma Antioksidan ve Oksidan Enzim Düzeyine Etkisi

Year 2019, Volume: 10 Issue: 4, 357 - 361, 13.12.2019

Rüveyda Esra Erçim Tuğçe Atçalı Burhanettin Baydaş

Abstract

Bu araştırma, soğuk stres
uygulanan ratlarda nar çiçeğinin (Punica Granatum), plazma total antioksidan
düzeyine, plazma toplam oksidan duruma ve Paraoksanaz1 enzim düzeyine olası
etkilerini araştırmak amacıyla planlanmıştır. Deneysel bir araştırma olan bu
çalışmada, ortalama 9 haftalık, 24 adet Wistar Albino erkek rat kullanılmıştır.
Ratlar rasgele sağlıklı kontrol (G1), soğuk stres uygulanmış kontrol (G2), soğuk
stres ve nar çiçeği ekstraktı uygulanan grup (G3) olmak üzere 3 gruba
ayrılmıştır. Deney gruplarına göre, grupların toplam antioksidan kapasite (TAC)
değerleri incelendiğinde, soğuk stres uygulanıp narçiçeği verilen grupta diğer
gruplara göre anlamlı derecede yüksek bulunmuştur (p=0,005). Yine bu grupta,
PON1 enzimi diğer gruplara göre daha yüksek olduğu bulunmuş, ancak anlamlı bir
fark saptanmamıştır (p=0,968). Oksidan parametrelerden TOS değeri, soğuk stres
uygulanıp narçiçeği verilen grupta diğer gruplara göre düşük bulunurken
(p=0,941), oksidatif stres indeksi de benzer şekilde bu grupta düşük
bulunmuştur (0=0,05). Bu çalışmada bazı parametreler açısından anlamlı sonuçlar
saptanmamış olmasına rağmen, nar çiçeğinin  antioksidan özelliğinin soğuk stres durumunda değişmelere
etkisi anlamlıdır. Soğuk strese karşı nar çiçeği çayının tüketilmesi
antioksidan kapasitenin artırılarak, organizmanın korunmasında yardımcı
olabilir. 

Keywords

soğuk stres, nar çiçeği, punica granatum, antioksidan kapasite

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