Nanocellulose Containing Polymethyl Methacrylate Bone Cements: Effect of Production Process and Silanization on Mechanical Characteristics

Year 2019, Volume: 10 Issue: 4, 436 - 443, 13.12.2019

Ümran Sezer

Abstract

Bone cement is one of the essential orthopedic materials in clinical
applications for fixing hip implants. However, the use of bone cement is
subject to some limitations like mechanical mismatch with the implantation
site. Despite the use of some fillers and bone cement formulations to tackle
these limitations, there is still a need for better solutions. It is possible
for nanocellulose (NC) to yield successful results in creating a formulation
with bone cements thanks to its natural, crystal and strong structure. In this
study, the mechanical performance of bone cements containing NC that is
produced with varying methods, and varying ratios in bone cement was examined.
Moreover, a comparative study by the silanization method; which is used for
enhancing the inter-phase compatibility in composite technology; and employing
the same ratios in NC formulations with silanized and non-silanized particles
was conducted. The results revealed that the silanization of NC does not create
a difference in mechanical strength compared to the non-silanized formulation,
however, a significant difference was detected with NC produced by different
drying methods.  

Keywords

nanocellulose, bone cement, silanization, sprya-drying, freeze-drying

Supporting Institution

Süleyman Demirel Üniversitesi BAP

Project Number

TSG-2018-6749 Project

Thanks

The author gratefully acknowledges the financial support for this work provided by the Suleyman Demirel University BAP (TSG-2018-6749 Project). The author also thanks to Zeynep Kocer and Isa Sahin for their help to synthesis of nanocellulose.

Nanocellulose Containing Polymethyl Methacrylate Bone Cements: Effect of Production Process and Silanization on Mechanical Characteristics

Abstract

Kemik
çimentosu, kalça implantlarını sabitlemek için klinik uygulamalarda gerekli
ortopedik malzemelerden biridir. Bununla birlikte, kemik çimentosu kullanımı,
implantasyon bölgesi ile mekanik uyumsuzluk gibi bazı sınırlamalara tabidir. Bu
sınırlamaların üstesinden gelmek için bazı dolgu maddelerinin ve kemik
çimentosu formülasyonlarının kullanılmasına rağmen, daha iyi çözümlere hala
ihtiyaç vardır. Nanoselülozun (NC), doğal, kristal ve güçlü yapısı sayesinde
kemik çimentoları ile formülasyon oluşturmada başarılı sonuçlar vermesi
mümkündür. Bu çalışmada, değişik yöntemlerle üretilen NC içeren kemik
çimentolarının mekanik performansını ve kemik çimentosundaki değişken
oranlarını incelenmiştir. Ayrıca, silanizasyon yöntemiyle karşılaştırmalı bir
çalışma ile kompozit teknolojide fazlar arası uyumluluğun arttırılması için kullanılan
ve aynı oranların silanize edilmiş ve silanize edilmemiş parçacıklarla NC
formülasyonlarında kullanılması araştırılmıştır. Sonuçlar, NC silanizasyonunun,
silanize edilmemiş formülasyona kıyasla mekanik mukavemette bir fark
yaratmadığını ortaya koymuş, ancak farklı kurutma yöntemleri ile üretilen NC
ile önemli fark tespit edilmiştir.

Keywords

nanoselüloz, kenik çimentasu, silanizasyon, sprey-kurutma, dondur-kurutma

Project Number

TSG-2018-6749 Project

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