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Evaluation of Depression and Anxiety Levels in Periodontal Diseases

Year 2023, Volume: 14 Issue: 1, 11 - 21, 13.04.2023
https://doi.org/10.22312/sdusbed.1226465

Abstract

Objective: The aim of this study is to evaluate the association between periodontal diseases and periodontal disease awareness and depression and anxiety levels.
Matherial-Method: In total 200 individuals (85 males and 115 females, aged 18-64 years) were included in the study, divided into 67 periodontal healthy individuals (PS group), 70 patients with gingivitis (G group), and 63 patients with periodontitis (P group). The clinical periodontal indexes and complaints of the participants, which is described periodontal disease awareness, were recorded. Depression and anxiety levels of the participants were evaluated by Beck depression and Beck anxiety scales.
Results: Beck depression and anxiety scores were higher in the P and G groups than in the PD group (P=0.001). Depression and anxiety scores were higher in patients who had complaints of gingival bleeding, sensitivity, bad breath, and aesthetic problems compared to those who did not have complaints. Depression scores were higher in patients who had mobility and abscess complaints (P 0.005). In multivariate Binary logistic regression analyses, Beck depression scores were 11.95 fold higher (95% CI: 3.1-46.06, P=0.001) in the P group than PS group. Beck depression scores were 4.61 fold higher in presence of sensitivity (95% CI: 1.58-13.43, P=0.005) and 3.73 fold in mobility (95% CI: 1.12-12.44, P=0.032) complaints than the apsence of these complaints.
Conclusion: Presence of periodontal diseases affect depression and anxiety levels. Periodontal disease awareness and depression can be associated. Depression can affect the progress of periodontal diseases.

References

  • [1] Hajishengallis G, Lamont RJ. 2021. Polymicrobial communities in periodontal disease: Their quasi-organismal nature and dialogue with the host. Periodontol 2000, 86(1):210-230.
  • [2] Genco RJ. 1996. Current View of Risk Factors for Periodontal Diseases. J Periodontol, 67 Suppl 10S:1041-1049.
  • [3] Castro GD, Oppermann RV, Haas AN, Winter R, Alchieri JC. 2006. Association between psychosocial factors and periodontitis: a case-control study. J Clin Periodontol, 33(2):109-114.
  • [4] Irwin M, Patterson T, Smith TL, Caldwell C, Brown SA, Gillin JC, Grant I. 1990. Reduction of immune function in life stress and depression. Biol Psychiatry, 27(1):22-30.
  • [5] Biondi M, Zannino LG. 1997. Psychological stress, neuroimmunomodulation, and susceptibility to infectious diseases in animals and man: a review. Psychother Psychosom, 66(1):3-26.
  • [6] Park J, Moghaddam B. 2017. Impact of anxiety on prefrontal cortex encoding of cognitive flexibility. Neuroscience, 345:193-202.
  • [7] Ramirez K, Fornaguera-Trías J, Sheridan JF. 2017. Stress-Induced Microglia Activation and Monocyte Trafficking to the Brain Underlie the Development of Anxiety and Depression. Curr Top Behav Neurosci, 31:155-172.
  • [8] Renoir T, Hasebe K, Gray L. 2013. Mind and body: how the health of the body impacts on neuropsychiatry. Front Pharmacol, 4:158.
  • [9] Kisely S, Sawyer E, Siskind D, Lalloo R. 2016. The oral health of people with anxiety and depressive disorders - a systematic review and meta-analysis. J Affect Disord, 200:119-132.
  • [10] Zheng DX, Kang XN, Wang YX, Huang YN, Pang CF, Chen YX, Kuang ZL, Peng Y. 2021. Periodontal disease and emotional disorders: A meta-analysis. J Clin Periodontol, 48(2):180-204.
  • [11] Buchberger B, Huppertz H, Krabbe L, Lux B, Mattivi JT, Siafarikas A. 2016. Symptoms of depression and anxiety in youth with type 1 diabetes: A systematic review and meta-analysis. Psychoneuroendocrinology, 70:70-84.
  • [12] Laforgia A, Corsalini M, Stefanachi G, Pettini F, Di Venere D. 2015. Assessment of Psychopatologic Traits in a Group of Patients with Adult Chronic Periodontitis: Study on 108 Cases and Analysis of Compliance during and after Periodontal Treatment. Int J Med Sci, 12(10):832-839.
  • [13] Sezer U, Ustun K, Senyurt SZ, Ciftci ME, Erciyas K. 2012. The evaluation of anxiety in periodontal patients. Cumhuriyet Dent J, 15: 297-306.
  • [14] Bilgin Çetin M, Sezgin Y. 2020. Periodontal Hastalık Öz Farkındalığının ve Potansiyel İlişkili Faktörlerin Değerlendirilmesi. Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi. 11(4): 407-415.
  • [15] B Özhayat EB. 2013. Influence of negative affectivity and self-esteem on the oral health related quality of life in patients receiving oral rehabilitation. Health Qual Life Outcomes, 11:178.
  • [16] Acharya S, Pentapati KC. 2012. Work stress and oral health-related quality of life among Indian information technology workers: an exploratory study. Int Dent J, 62(3):132-136.
  • [17] Mento C, Lombardo C, Milazzo M, Whithorn NI, Boronat-Catalá M, Almiñana-Pastor PJ, Fernàndez CS, Bruno A, Muscatello MRA, Zoccali RA. 2021. Adolescence, Adulthood and Self-Perceived Halitosis: A Role of Psychological Factors. Medicina (Kaunas), 57(6).
  • [18] Silness J, Loe H. 1964. Periodontal Disease in Pregnancy. Ii. Correlation between Oral Hygiene and Periodontal Condtion. Acta Odontol Scand, 22:121-135.
  • [19] Loe H. 1967. The Gingival Index, the Plaque Index and the Retention Index Systems. J Periodontol, 38(6):Suppl:610-616.
  • [20] Ainamo J, Bay I. 1975. Problems and proposals for recording gingivitis and plaque. Int Dent J, 25(4):229-235.
  • [21] Tonetti MS, Sanz M. 2019. Implementation of the new classification of periodontal diseases: Decision-making algorithms for clinical practice and education. J Clin Periodontol, 46(4):398-405.
  • [22] Tonetti MS, Greenwell H, Kornman KS. 2018. Staging and grading of periodontitis: Framework and proposal of a new classification and case definition. J Clin Periodontol, 45 Suppl 20:S149-s161.
  • [23] Hisli N. 1989. Validity and accuracy of Beck depression inventory among university students (InTurkish). Psikoloji Dergisi, 3-13.
  • [24] Vural M, Satiroglu O, Akbas B, Goksel I, Karabay O. 2009. Coronary artery disease in association with depression or anxiety among patients undergoing angiography to investigate chest pain. Tex Heart Inst J, 36(1):17-23.
  • [25] Ulusoy MS, NH, Erkmen H. 1998. Turkish version of theBeck Anxiety Inventory: psychometric properties. J Cogn Psycother Int Q 1998; 12:163-172.
  • [26] Hsu CC, Hsu YC, Chen HJ, Lin CC, Chang KH, Lee CY, Chong LW, Kao CH. 2015. Association of Periodontitis and Subsequent Depression: A Nationwide Population-Based Study. Medicine (Baltimore), 94(51):e2347.
  • [27] Köhler CA, Freitas TH, Maes M, et al. 2017. Peripheral cytokine and chemokine alterations in depression: a meta-analysis of 82 studies. Acta Psychiatr Scand, 135(5):373-387.
  • [28] Klages U, Weber AG, Wehrbein H. 2005. Approximal plaque and gingival sulcus bleeding in routine dental care patients: relations to life stress, somatization and depression. J Clin Periodontol, 32(6):575-582.
  • [29] Ababneh KT, Taha AH, Abbadi MS, Karasneh JA, Khader YS. 2010. The association of aggressive and chronic periodontitis with systemic manifestations and dental anomalies in a jordanian population: a case control study. Head Face Med, 6:30.
  • [30] Choi J, Price J, Ryder S, Siskind D, Solmi M, Kisely S. 2022. Prevalence of dental disorders among people with mental illness: An umbrella review. Aust N Z J Psychiatry, 56(8):949-963.
  • [31] Petit C, Anadon-Rosinach V, Rettig L, Schmidt-Mutter C, Tuzin N, Davideau JL, Huck O. 2021. Influence of psychological stress on non-surgical periodontal treatment outcomes in patients with severe chronic periodontitis. J Periodontol, 92(2):186-195.
  • [32] Johannsen A, Rydmark I, Söder B, Asberg M. 2007. Gingival inflammation, increased periodontal pocket depth and elevated interleukin-6 in gingival crevicular fluid of depressed women on long-term sick leave. J Periodontal Res, 42(6):546-552.
  • [33] Genco RJ, Ho AW, Grossi SG, Dunford RG, Tedesco LA. 1999. Relationship of stress, distress and inadequate coping behaviors to periodontal disease. J Periodontol, 70(7):711-723.
  • [34] Hwang SH, Park SG. 2018. The relationship between depression and periodontal diseases. Community Dent Health, 35(1):23-29.
  • [35] Aleksejuniené J, Holst D, Eriksen HM, Gjermo P. 2002. Psychosocial stress, lifestyle and periodontal health. J Clin Periodontol, 29(4):326-335.

Periodontal Hastalıklarda Depresyon ve Anksiyete Düzeylerinin Değerlendirilmesi

Year 2023, Volume: 14 Issue: 1, 11 - 21, 13.04.2023
https://doi.org/10.22312/sdusbed.1226465

Abstract

Amaç: Bu çalışmanın amacı, periodontal hastalıkların ve periodontal hastalık farkındalığının depresyon ve anksiyete düzeyleri ile ilişkisini değerlendirmektir.
Materyal-Metot: Çalışmaya toplamda 200 birey (85 erkek ve 115 kadın, 18-64 yaş aralığı) olmak üzere, 67 periodontal sağlıklı (PS grup) birey, 70 Gingivitis hastası (G grup) ve 63 Periodontitis hastası (P grup) dahil edildi. Katılımcıların klinik periodontal klinik indeksleri ve periodontal hastalık farkındalıklarına ilişkin şikayetleri kaydedildi. Hastaların depresyon ve anksiyete seviyeleri Beck deresyon ve anksiyete ölçekleriyle değerlendirildi.
Bulgular: Beck depresyon ve anksiyete skorları P ve G gruplarında PS grubundan daha yüksekti (P=0.001). Dişeti kanaması, hassasiyet, ağız kokusu, estetik problem şikâyeti olan hastalarda depresyon ve anksiteye skorları şikâyeti olmayanlara göre daha yüksekti (P0.005). Mobilite ve apse şikâyeti olan hastalarda depresyon skorları şikâyeti olmayanlara göre daha yüksekti (P0.005). Çok değişkenli Binary lojistik regresyon analizinde Beck depresyon skoru P grubundan PS grubuna doğru gittikçe 11,95 (%95 GA: 3,1-46,06, P=0.001) kat artmıştır. Hassasiyet şikâyeti varlığı, Beck depresyon skorunu şikâyetin yokluğuna göre 4,61 kat arttırırken (%95 GA: 1,58-13,43, P=0.005); mobilite şikâyeti varlığı skoru 3,73 kat arttırmıştır (%95 GA: 1,12-12,44, P=0.032).
Sonuç: Periodontal hastalık varlığı depresyon ve anksiyete düzeylerini etkileyebilir ve periodontal hastalık farkındalığı ile depresyon ilişkili olabilir. Depresyon periodontal hastalıkların seyrini etkileyebilir.

References

  • [1] Hajishengallis G, Lamont RJ. 2021. Polymicrobial communities in periodontal disease: Their quasi-organismal nature and dialogue with the host. Periodontol 2000, 86(1):210-230.
  • [2] Genco RJ. 1996. Current View of Risk Factors for Periodontal Diseases. J Periodontol, 67 Suppl 10S:1041-1049.
  • [3] Castro GD, Oppermann RV, Haas AN, Winter R, Alchieri JC. 2006. Association between psychosocial factors and periodontitis: a case-control study. J Clin Periodontol, 33(2):109-114.
  • [4] Irwin M, Patterson T, Smith TL, Caldwell C, Brown SA, Gillin JC, Grant I. 1990. Reduction of immune function in life stress and depression. Biol Psychiatry, 27(1):22-30.
  • [5] Biondi M, Zannino LG. 1997. Psychological stress, neuroimmunomodulation, and susceptibility to infectious diseases in animals and man: a review. Psychother Psychosom, 66(1):3-26.
  • [6] Park J, Moghaddam B. 2017. Impact of anxiety on prefrontal cortex encoding of cognitive flexibility. Neuroscience, 345:193-202.
  • [7] Ramirez K, Fornaguera-Trías J, Sheridan JF. 2017. Stress-Induced Microglia Activation and Monocyte Trafficking to the Brain Underlie the Development of Anxiety and Depression. Curr Top Behav Neurosci, 31:155-172.
  • [8] Renoir T, Hasebe K, Gray L. 2013. Mind and body: how the health of the body impacts on neuropsychiatry. Front Pharmacol, 4:158.
  • [9] Kisely S, Sawyer E, Siskind D, Lalloo R. 2016. The oral health of people with anxiety and depressive disorders - a systematic review and meta-analysis. J Affect Disord, 200:119-132.
  • [10] Zheng DX, Kang XN, Wang YX, Huang YN, Pang CF, Chen YX, Kuang ZL, Peng Y. 2021. Periodontal disease and emotional disorders: A meta-analysis. J Clin Periodontol, 48(2):180-204.
  • [11] Buchberger B, Huppertz H, Krabbe L, Lux B, Mattivi JT, Siafarikas A. 2016. Symptoms of depression and anxiety in youth with type 1 diabetes: A systematic review and meta-analysis. Psychoneuroendocrinology, 70:70-84.
  • [12] Laforgia A, Corsalini M, Stefanachi G, Pettini F, Di Venere D. 2015. Assessment of Psychopatologic Traits in a Group of Patients with Adult Chronic Periodontitis: Study on 108 Cases and Analysis of Compliance during and after Periodontal Treatment. Int J Med Sci, 12(10):832-839.
  • [13] Sezer U, Ustun K, Senyurt SZ, Ciftci ME, Erciyas K. 2012. The evaluation of anxiety in periodontal patients. Cumhuriyet Dent J, 15: 297-306.
  • [14] Bilgin Çetin M, Sezgin Y. 2020. Periodontal Hastalık Öz Farkındalığının ve Potansiyel İlişkili Faktörlerin Değerlendirilmesi. Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi. 11(4): 407-415.
  • [15] B Özhayat EB. 2013. Influence of negative affectivity and self-esteem on the oral health related quality of life in patients receiving oral rehabilitation. Health Qual Life Outcomes, 11:178.
  • [16] Acharya S, Pentapati KC. 2012. Work stress and oral health-related quality of life among Indian information technology workers: an exploratory study. Int Dent J, 62(3):132-136.
  • [17] Mento C, Lombardo C, Milazzo M, Whithorn NI, Boronat-Catalá M, Almiñana-Pastor PJ, Fernàndez CS, Bruno A, Muscatello MRA, Zoccali RA. 2021. Adolescence, Adulthood and Self-Perceived Halitosis: A Role of Psychological Factors. Medicina (Kaunas), 57(6).
  • [18] Silness J, Loe H. 1964. Periodontal Disease in Pregnancy. Ii. Correlation between Oral Hygiene and Periodontal Condtion. Acta Odontol Scand, 22:121-135.
  • [19] Loe H. 1967. The Gingival Index, the Plaque Index and the Retention Index Systems. J Periodontol, 38(6):Suppl:610-616.
  • [20] Ainamo J, Bay I. 1975. Problems and proposals for recording gingivitis and plaque. Int Dent J, 25(4):229-235.
  • [21] Tonetti MS, Sanz M. 2019. Implementation of the new classification of periodontal diseases: Decision-making algorithms for clinical practice and education. J Clin Periodontol, 46(4):398-405.
  • [22] Tonetti MS, Greenwell H, Kornman KS. 2018. Staging and grading of periodontitis: Framework and proposal of a new classification and case definition. J Clin Periodontol, 45 Suppl 20:S149-s161.
  • [23] Hisli N. 1989. Validity and accuracy of Beck depression inventory among university students (InTurkish). Psikoloji Dergisi, 3-13.
  • [24] Vural M, Satiroglu O, Akbas B, Goksel I, Karabay O. 2009. Coronary artery disease in association with depression or anxiety among patients undergoing angiography to investigate chest pain. Tex Heart Inst J, 36(1):17-23.
  • [25] Ulusoy MS, NH, Erkmen H. 1998. Turkish version of theBeck Anxiety Inventory: psychometric properties. J Cogn Psycother Int Q 1998; 12:163-172.
  • [26] Hsu CC, Hsu YC, Chen HJ, Lin CC, Chang KH, Lee CY, Chong LW, Kao CH. 2015. Association of Periodontitis and Subsequent Depression: A Nationwide Population-Based Study. Medicine (Baltimore), 94(51):e2347.
  • [27] Köhler CA, Freitas TH, Maes M, et al. 2017. Peripheral cytokine and chemokine alterations in depression: a meta-analysis of 82 studies. Acta Psychiatr Scand, 135(5):373-387.
  • [28] Klages U, Weber AG, Wehrbein H. 2005. Approximal plaque and gingival sulcus bleeding in routine dental care patients: relations to life stress, somatization and depression. J Clin Periodontol, 32(6):575-582.
  • [29] Ababneh KT, Taha AH, Abbadi MS, Karasneh JA, Khader YS. 2010. The association of aggressive and chronic periodontitis with systemic manifestations and dental anomalies in a jordanian population: a case control study. Head Face Med, 6:30.
  • [30] Choi J, Price J, Ryder S, Siskind D, Solmi M, Kisely S. 2022. Prevalence of dental disorders among people with mental illness: An umbrella review. Aust N Z J Psychiatry, 56(8):949-963.
  • [31] Petit C, Anadon-Rosinach V, Rettig L, Schmidt-Mutter C, Tuzin N, Davideau JL, Huck O. 2021. Influence of psychological stress on non-surgical periodontal treatment outcomes in patients with severe chronic periodontitis. J Periodontol, 92(2):186-195.
  • [32] Johannsen A, Rydmark I, Söder B, Asberg M. 2007. Gingival inflammation, increased periodontal pocket depth and elevated interleukin-6 in gingival crevicular fluid of depressed women on long-term sick leave. J Periodontal Res, 42(6):546-552.
  • [33] Genco RJ, Ho AW, Grossi SG, Dunford RG, Tedesco LA. 1999. Relationship of stress, distress and inadequate coping behaviors to periodontal disease. J Periodontol, 70(7):711-723.
  • [34] Hwang SH, Park SG. 2018. The relationship between depression and periodontal diseases. Community Dent Health, 35(1):23-29.
  • [35] Aleksejuniené J, Holst D, Eriksen HM, Gjermo P. 2002. Psychosocial stress, lifestyle and periodontal health. J Clin Periodontol, 29(4):326-335.
There are 35 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Araştırma Articlesi
Authors

Ayşegül Sarı 0000-0001-6180-9776

Publication Date April 13, 2023
Submission Date December 29, 2022
Published in Issue Year 2023 Volume: 14 Issue: 1

Cite

Vancouver Sarı A. Periodontal Hastalıklarda Depresyon ve Anksiyete Düzeylerinin Değerlendirilmesi. Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi. 2023;14(1):11-2.

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