Investigation of In vitro Anti-Tyrosinase, Anti-Collagenase, Anti-Elastase and Anti-Hyaluronidase Effects of New Generation Cosmetic Peptide Argireline (Acetyl Hexapeptide-8) Molecule

Yıl 2023, Cilt: 14 Sayı: 2, 227 - 234, 15.08.2023

Basak Gokce

https://doi.org/10.22312/sdusbed.1330756

Öz

This study was designed to evaluate the alteration of the new generation cosmetic peptide argireline molecule on some enzyme activities involved in skin aging processes. Tyrosinase, collagenase, elastase and hyaluronidase enzymes are the enzymes that attract attention due to their direct and therapeutic effects in skin aging. High elastase inhibition anti-wrinkle, tyrosinase inhibition whitening effect, collagenase inhibition elasticity and hyaluronidase inhibition anti-inflammation effect. For this reason, the effectiveness of the argireline molecule, which has been used as a trend in cosmetics recently, has been studied. Considering the overall activities tested, the argireline compound was judged to be a promising anti-aging compound.

Anahtar Kelimeler

Argireline, tyrosinase, collegenase, elastase, and hyaluronidase

Yeni Nesil Kozmetik Peptid Argireline (Asetil heksapeptid-8) Molekülünün in vitro Anti-Tirozinaz, Anti-Kollajenaz, Anti-Elastaz ve Anti Hyalüronidaz Etkilerinin Araştırılması

Öz

Bu çalışma, yeni nesil kozmetik peptid argireline molekülünün cilt yaşlanma süreçlerinde yer alan bazı enzim aktiviteleri üzerindeki değişimini değerlendirmek için tasarlanmıştır. Tirozinaz, kolejenaz, elastaz ve hiyalüronidaz enzimleri cilt yaşlanmasında, doğrudan ve terapötik etkileri nedeniyle dikkat çeken enzimlerdir. Yüksek elastaz inhibisyonu kırışıklık önleyici, tirozinaz inhibisyonu beyazlatma etkili, kolejenaz inhibisyonu esneklik ve hyalüronidaz inhibisyonu anti-inflamasyon etkisi göstermektedir. Bu nedenle, son dönemlerde kozmetikte trend olarak kullanılan argireline molekülünün, etkinliği çalışılmıştır. Test edilen genel aktiviteler göz önüne alındığında, argireline bileşiğinin umut verici yaşlanma karşıtı bileşik olduğu değerlendirilmiştir.

Anahtar Kelimeler

Argireline, tirozinaz, kollajenaz, elastaz, ve hyalüronidaz

Kaynakça

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