ANAPHYLAXIS IN CHILDREN: SINGLE CENTER EXPERIENCE

Abstract

Objective Anaphylaxis is a sudden-onset, life-threatening, systemic allergic reaction. In this study, we aimed to evaluate the demographic characteristics, clinical findings, triggers of anaphylaxis, and the use of adrenaline in first-line treatment in pediatric patients with anaphylaxis. Material and Method Patients aged 0-18 years who were followed up with a diagnosis of anaphylaxis in the pediatric allergy department between May 2021 and October 2023 were evaluated. Demographic characteristics, anaphylaxis diagnosis and treatment registry of patients with anaphylaxis were evaluated. Results A total of 46 anaphylaxis patients were evaluated. Twenty-eight (61%) of the patients were male, and the median age was 3.5 years (range: 1–10). The three most common triggers in all age groups were food (61%), drugs (20%), and insect venom (20%), respectively. Milk was the most common trigger responsible for anaphylaxis among foods (22%). 28% of the cases were followed up with a diagnosis of severe anaphylaxis. The rate of adrenaline use at the initial presentation was 52%. Conclusion Foods are the triggers most responsible for anaphylaxis in early childhood. The rate of adrenaline use at first presentation is very low. Training programs should be organized for all healthcare professionals on the diagnosis and treatment of anaphylaxis.

Keywords

• Anaphylaxis
• child
• adrenaline

ÇOCUKLUK DÖNEMİNDE ANAFİLAKSİ: TEK MERKEZ DENEYİMİ

Abstract

Amaç Anafilaksi ani başlangıçlı, hayatı tehdit eden, sistemik alerjik bir reaksiyondur. Bu çalışmada anafilaksi tanısı ile takip ettiğimiz olguların demografik özelliklerini, klinik bulgularını, anafilaksi tetikleyicilerini ve ilk basamak tedavide adrenalin kullanım durumunu değerlendirmeyi amaçladık. Gereç ve Yöntem Mayıs 2021- Ekim 2023 tarihleri arasında çocuk alerji bölümünde anafilaksi tanısı ile takip edilen 0-18 yaş arasındaki hastalar incelendi. Anafilaksi tanısı alan olguların demografik özellikleri ve anafilaksi tanı ve tedavi kayıt bilgileri değerlendirildi. Bulgular Toplam 46 anafilaksi hastası değerlendirildi. Hastaların 28’i (%61) erkek olup, ortanca yaş 3,5 (ÇAU: 1-10) yıl idi. Tüm yaş gruplarında en sık 3 tetikleyici sırasıyla besin (%61), ilaç (%20) ve böcek zehiri (%20) idi. Süt, besinler içinde anafilaksiden en çok sorumlu tetikleyici idi (%22). Olguların %28’ i ağır anafilaksi tanısı ile takip ediliyordu. Birinci basamak tedavisinde adrenalin kullanım oranı %52 idi. Sonuç Besinler erken çocukluk döneminde anafilaksiden en çok sorumlu olan tetikleyicilerdir. İlk başvuruda adrenalin kullanım oranı oldukça düşüktür. Anafilaksi tanı ve tedavisine yönelik tüm sağlık çalışanlarına yönelik eğitim programları verilmelidir.

Keywords

• Anafilaksi
• çocuk
• adrenalin

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